2-[(5S)-5-丙基二氢-2(3H)-呋喃亚基]-1,3-环戊烷二酮 | 31323-50-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四氢呋喃
• 中文名称: 2-[(5S)-5-丙基二氢-2(3H)-呋喃亚基]-1,3-环戊烷二酮
• 英文名称: Oudenone
• 英文别名: Ondenon；2-[(5S)-5-propyloxolan-2-ylidene]cyclopentane-1,3-dione
• CAS: 31323-50-9
• 化学式: C₁₂H₁₆O₃
• 分子量: 208.257
• InChiKey: AFHDYMGMZUYZQT-QMMMGPOBSA-N

物化性质

• 熔点：
  77.5°C
• 沸点：
  255.5°C (estimate)
• 密度：
  1.1227 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

安全信息

• 海关编码：
  2932190090

文献信息

• Filler for measuring enzyme activity, column packed with the filler, and method of measuring enzyme activity using the column
  申请人：SHOWA DENKO KABUSHIKI KAISHA

  公开号：EP0329190A2

  公开（公告）日：1989-08-23

  Enzyme activity is measured promptly with a high accuracy by introducing an enzyme, the activity of which is to be measured, into a column comprising a hollow tube packed with a filler comprising a support and a substrate that can be recognized by the enzyme, which is immobilized on the support, and measuring the amount of the obtained decomposition product of the substrate.

  酶的活性是通过将需要测量其活性的酶导入一个由空心管组成的柱中，空心管中填充物包括支撑物和可被固定在支撑物上的酶识别的底物，然后测量所获得的底物分解产物的量，从而快速、高精度地测量酶的活性。
• NMN AND DERIVATIVES FOR ITS USE IN THE TREATMENT OF DEPRESSION AND/OR ANXIETY IN PATIENTS HAVING A FORM OF PARKINSONISM
  申请人：Nuvamid SA

  公开号：EP4079311A1

  公开（公告）日：2022-10-26

  The invention relates to compounds of formula (I) and/or of formula (Ia) for the prevention and/or treatment of depression and/or anxiety related to a Parkinsonism such as an alpha-synucleinopathy as well as compositions and kit of parts comprising the same.

  本发明涉及用于预防和/或治疗与帕金森病（如α-突触核蛋白病）相关的抑郁和/或焦虑症的式(I)和/或式(Ia)化合物，以及包含这些化合物的组合物和试剂盒。
• Compositions and methods for treating autism
  申请人：HOFFMAN TECHNOLOGIES LLC

  公开号：US10751313B2

  公开（公告）日：2020-08-25

  The invention provides compositions and methods of treating autism. Specifically, the invention relates to treating the core symptoms of autism by administering α-methyl-DL-tyrosine.

  本发明提供了治疗自闭症的组合物和方法。具体而言，本发明涉及通过施用α-甲基-DL-酪氨酸来治疗自闭症的核心症状。
• Treatment of dermatological conditions via neuromodulation
  申请人：Palo Alto Investors

  公开号：US11383084B2

  公开（公告）日：2022-07-12

  Methods for treating a subject for a dermatological condition are provided. Aspects of the invention include administering an effective amount of a neuromodulatory agent to a subject to treat the subject for the dermatological condition. Also provided are compositions, kits and systems for practicing the subject methods.

  本发明提供了治疗受试者皮肤病的方法。本发明的各个方面包括向受试者施用有效量的神经调节剂，以治疗受试者的皮肤病。本发明还提供了用于实施上述方法的组合物、试剂盒和系统。
• IMMUNOMODULATORY COMPOSITIONS COMPRISING HYDRALAZINE FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS
  申请人：Sigmoid Pharma Limited

  公开号：EP2642978A2

  公开（公告）日：2013-10-02