N-(3-nitrobenzenesulfonyl)-2-iodoaniline | 87317-03-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(3-nitrobenzenesulfonyl)-2-iodoaniline
• 英文别名: N-(2-Iodophenyl)-3-nitrobenzene-1-sulfonamide；N-(2-iodophenyl)-3-nitrobenzenesulfonamide
• CAS: 87317-03-1
• 化学式: C₁₂H₉IN₂O₄S
• 分子量: 404.185
• InChiKey: AVCWTYMQGVYRRE-UHFFFAOYSA-N

物化性质

• 沸点：
  502.4±60.0 °C(Predicted)
• 密度：
  1.902±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  100
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  1,2-二氢萘 、 N-(3-nitrobenzenesulfonyl)-2-iodoaniline 在 palladium diacetate 、 silver carbonate 作用下， 反应 1.5h， 以43%的产率得到11-(3-nitrophenylsulfonyl)-6,6a,11,11a-tetrahydro-5H-benzo[α]carbazole
  参考文献：
  名称：

  Synthesis of 11a-N-Arylsulfonyl-5-carbapterocarpans (Tetrahydro-5H-benzo[a]carbazoles) by Azaarylation of Dihydronaphthalenes with o-Iodo-N-(Arylsulfonyl)anilines in Poly(ethylene glycol)

  摘要：

  11a-N-Arylsulfonyl-5-carbapterocarpans (tetrahydro-5H-benzo[a]carbazoles) were synthesized by palladium-catalyzed azaarylation of dihydronaphthalenes with o-iodo-N-(arylsulfonyl) anilines in poly(ethylene glycol) (PEG-400). Better chemical yields (moderate to good) and shorter reaction times (a few minutes at 130-170 degrees C) were observed in PEG-400 compared with the corresponding reactions in acetone.

  DOI：

  10.1055/s-0034-1380757
• 作为产物：
  描述：

  2-碘苯胺 、 3-硝基苯磺酰氯 在 吡啶 作用下， 生成 N-(3-nitrobenzenesulfonyl)-2-iodoaniline
  参考文献：
  名称：

  Synthesis of 11a-N-Arylsulfonyl-5-carbapterocarpans (Tetrahydro-5H-benzo[a]carbazoles) by Azaarylation of Dihydronaphthalenes with o-Iodo-N-(Arylsulfonyl)anilines in Poly(ethylene glycol)

  摘要：

  11a-N-Arylsulfonyl-5-carbapterocarpans (tetrahydro-5H-benzo[a]carbazoles) were synthesized by palladium-catalyzed azaarylation of dihydronaphthalenes with o-iodo-N-(arylsulfonyl) anilines in poly(ethylene glycol) (PEG-400). Better chemical yields (moderate to good) and shorter reaction times (a few minutes at 130-170 degrees C) were observed in PEG-400 compared with the corresponding reactions in acetone.

  DOI：

  10.1055/s-0034-1380757

文献信息

• Synthesis of 11a-N-Arylsulfonyl-5-carbapterocarpans (Tetrahydro-5H-benzo[a]carbazoles) by Azaarylation of Dihydronaphthalenes with o-Iodo-N-(Arylsulfonyl)anilines in Poly(ethylene glycol)
  作者：Camilla Buarque、Ayres Dias、Paulo Costa、Julio Barcellos、Beatriz Borges、Joseane Mendes、Mauricio Ceron

  DOI：10.1055/s-0034-1380757

  日期：——

  11a-N-Arylsulfonyl-5-carbapterocarpans (tetrahydro-5H-benzo[a]carbazoles) were synthesized by palladium-catalyzed azaarylation of dihydronaphthalenes with o-iodo-N-(arylsulfonyl) anilines in poly(ethylene glycol) (PEG-400). Better chemical yields (moderate to good) and shorter reaction times (a few minutes at 130-170 degrees C) were observed in PEG-400 compared with the corresponding reactions in acetone.