2-[1-(2-羟基-3,5-二甲基苯基)乙基]-4,6-二甲基苯酚 | 3772-19-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-[1-(2-羟基-3,5-二甲基苯基)乙基]-4,6-二甲基苯酚
• 英文名称: 1,1-bis(2-hydroxy-3,5-dimethylphenyl)ethane
• 英文别名: 2,2'-ethylidenebis(4,6-dimethylphenol)；4,6,4',6'-tetramethyl-2,2'-ethylidene-di-phenol；4,6,4',6'-Tetramethyl-2,2'-aethyliden-di-phenol；1,1-Bis-(2-hydroxy-3,5-dimethyl-phenyl)-aethan；1,1-bis-(3,5-dimethyl-hydroxyphenyl)-ethane；1,1-Bis-(2-hydroxy-3,5-dimethyl-phenyl)-ethan；Phenol, 2,2'-ethylidenebis[4,6-dimethyl-；2-[1-(2-hydroxy-3,5-dimethylphenyl)ethyl]-4,6-dimethylphenol
• CAS: 3772-19-8
• 化学式: C₁₈H₂₂O₂
• 分子量: 270.371
• InChiKey: CBSMHURWAVXJSM-UHFFFAOYSA-N

物化性质

• 熔点：
  133 °C
• 沸点：
  406.9±40.0 °C(Predicted)
• 密度：
  1.089±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 海关编码：
  2907299090

反应信息

• 作为反应物：
  描述：

  2-[1-(2-羟基-3,5-二甲基苯基)乙基]-4,6-二甲基苯酚 、 乙酸酐 在 硫酸 作用下， 生成 1,1-bis-(2-acetoxy-3,5-dimethyl-phenyl)-ethane
  参考文献：
  名称：

  v. Euler; Adler; Cedwall, Arkiv foer Kemi, 1942, vol. 15 A, # 19, p. 1,4, 5, 8, 10

  摘要：

  DOI：
• 作为产物：
  描述：

  2,4-二甲基苯酚 在 甲醇 、 硫酸 、 mercury(II) sulfate 作用下， 生成 2-[1-(2-羟基-3,5-二甲基苯基)乙基]-4,6-二甲基苯酚
  参考文献：
  名称：

  v. Euler; Adler; Cedwall, Arkiv foer Kemi, 1942, vol. 15 A, # 19, p. 1,4, 5, 8, 10

  摘要：

  DOI：

文献信息

• Substituted Bisphenols as Antioxidants for Autoxidation of Tetralin
  作者：Fukiko Yamada、Tomihiro Nishiyama、Masahiro Yamamoto、Kazunori Tanaka

  DOI：10.1246/bcsj.62.3603

  日期：1989.11

  The antioxidative activities of nineteen compounds of seven series of alkylidene- and benzylidenebisphenols were evaluated by means of an oxygen-absorption method at 60 °C for tetralin. The electrochemical oxidation potentials determined using linear-sweep voltammetry and the 13C NMR chemical shifts (δ) of these compounds were obtained. These data were associated with the antioxidative activities.

  采用吸氧法在 60 °C 条件下对四氢萘的抗氧化活性进行了评价，研究了 7 个系列的亚烷基和亚苄基双酚的 19 种化合物的抗氧化活性。获得了使用线性扫描伏安法测定的电化学氧化电位和这些化合物的 13 C NMR 化学位移 (δ)。这些数据与抗氧化活性有关。特别是，发现诱导期 (min) 表现出的活性与 OH 取代基的同碳的 13C 化学位移密切相关 (corr. coeff. = 0.991)。已经观察到一系列 2,2'-亚烷基-和亚苄基双（4,6-二甲基苯酚）衍生物具有非常好的活性。
• Multidentate phosphite ligands, catalytic compositions containing such ligands, and catalytic prosses utilizing such catalytic compositions
  申请人：——

  公开号：US20030023110A1

  公开（公告）日：2003-01-30

  Multidentate phosphite ligands are disclosed for use in reactions such as hydrocyanation and isomerization. The catalyst compositions made therefrom and the various catalytic processes which employ such multidentate phosphite ligands are also disclosed. In particular, the ligands have heteroatom-containing substituents on the carbon attached to the ortho position of the terminal phenol group.

  多齿磷酸酯配体被用于反应，如氢氰化和异构化。由此制成的催化剂组合物以及采用这些多齿磷酸酯配体的各种催化过程也被披露。特别是，这些配体在连接到末端酚基的邻位碳上具有含杂原子的取代基。
• Hydroformylation of unsaturated compounds using polymeric phosphite ligands
  申请人：E.I. du Pont de Nemours and Company

  公开号：EP1430950A1

  公开（公告）日：2004-06-23

  The present invention provides a composition comprising a Group VIII metal and a polymeric phosphite composition comprising polymer A wherein said polymer A comprises repeat units derived from (a-i) a carbonyl compound; (a-ii) an amine monomer; and (a-iii) phosphochloridite having the formula CIP(O-Ar2-R2)2.

  本发明提供了一种包含第八族金属和聚合物 A 组成的聚合亚磷酸酯组合物，其中所述聚合物 A 包含源自以下物质的重复单元 (a-i) 羰基化合物； (a-ii) 一种胺单体；和 (a-iii) 具有 CIP(O-Ar2-R2)2 式的亚磷酸亚氯酸盐。
• Polymeric phosphite composition and hydrocyanation of unsaturated organic compounds and the isomerization of unsaturated nitriles
  申请人：——

  公开号：US20010049431A1

  公开（公告）日：2001-12-06

  A polymeric composition, a process for producing the composition, and a process for using the composition in, for example, hydrocyanation or isomerization are disclosed. The composition comprises repeat units derived from (1) a carbonyl compound, a monomer, and phosphorochloridite; (2) phosphorus trichloride, a polyhydric alcohol, and an aromatic diol; or (3) combinations of (1) and (2) in which the monomer can be a polyhydric alcohol, an amine, combinations thereof. The composition can further comprise a Group VIII metal and optionally a Lewis acid. The composition can be produced by (1) contacting a carbonyl compound with the monomer to produce an intermediate and contacting the intermediate with phosphorochloridite; (2) contacting phosphorus trichloride with a second polyhydric alcohol under a condition sufficient to produce a phosphorus-containing polymer and contacting the phosphorus-containing polymer with an aromatic diol; or (3) contacting an N,N-dialkyl dichlorophosphoramidite with a second polyhydric alcohol to produce a polymer phosphoramidite, contacting the polymer phosphoramidite with an acid such as HCl to produce the phospphorus-containing polymer, which is then contacted with an aromatic diol. The composition can be used as catalyst, for example, for converting an unsaturated organic compound to a nitrile and isomerizing a nitrile.

  本发明公开了一种聚合物组合物、一种生产该组合物的工艺以及一种将该组合物用于例如加氢氰化或异构化的工艺。该组合物包含由以下物质衍生的重复单元：(1) 羰基化合物、单体和亚磷酸根；(2) 三氯化磷、多元醇和芳香族二元醇；或 (3) (1) 和 (2) 的组合，其中单体可以是多元醇、胺或它们的组合。组合物还可进一步包含第八族金属和可选的路易斯酸。该组合物可通过以下方法制得：(1) 将羰基化合物与单体接触，生成中间体，并将中间体与亚磷酸三氯化磷接触；(2) 在足以生成含磷聚合物的条件下，将三氯化磷与第二种多元醇接触，并将含磷聚合物与芳香族二元醇接触；或 (3) 将 N,N-二烷基二氯亚磷酰胺与第二种多元醇接触，生成聚合物亚磷酰胺，将聚合物亚磷酰胺与盐酸等酸接触，生成含磷聚合物，然后将其与芳香族二元醇接触。该组合物可用作催化剂，例如用于将不饱和有机化合物转化为腈和将腈异构化。
• HYDROFORMYLATION PROCESS UTILIZING MULTIDENTATE PHOSPHITE LIGANDS
  申请人：INVISTA Technologies S.à.r.l.

  公开号：EP1214282B1

  公开（公告）日：2005-02-23