thiohydantoic acid hydrazide | 14586-05-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: thiohydantoic acid hydrazide
• 英文别名: 4-thio-hydantoic acid hydrazide；N-Thiocarbamoyl-glycin-hydrazid；4-Thio-hydantoinsaeure-hydrazid；4-Thiohydantoinsaeure-hydrazid；1-(Hydrazinocarbonylmethyl)-2-thiourea；(2-hydrazinyl-2-oxoethyl)thiourea
• CAS: 14586-05-1
• 化学式: C₃H₈N₄OS
• mdl: MFCD19205183
• 分子量: 148.189
• InChiKey: DOASTZHFUWYSRH-UHFFFAOYSA-N

物化性质

• 熔点：
  190 °C (decomp)
• 密度：
  1.409±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.8
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  125
• 氢给体数：
  4
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-硫代乙内酰脲 在 肼氢醌络合物 作用下， 反应 1.0h， 以100%的产率得到thiohydantoic acid hydrazide
  参考文献：
  名称：

  Solid-state reactivity of the hydrazine-hydroquinone complex

  摘要：

  The solid-state reactivities of the hydrazine-hydroquinone 1:1 complex and of hydrazine hydrochloride with solid aldehydes, ketones, carboxylic acids, thiohydantoin and 4-nitrophenyl isothiocyanate were investigated. Only the hydrazine complex provides quantitative additions, condensations, ring openings and ring closures. The solid-state mechanisms were investigated by atomic force microscopy (AFM) and the Ear-reaching anisotropic molecular movements are correlated with the crystal packing, both on the hydrazine complex surface and on the surface of two benzaldehydes. The hydrazine moves into the aldehyde crystals for chemical reaction without melting. Characteristic surface features are created by the common phase rebuilding and phase transformation on both the hydrazine-donating and -accepting crystals. Copyright (C) 2000 John Wiley & Sons, Ltd. Additional material for this paper is available from the epoc website at http://www.wiley.com/epoc.

  DOI：

  10.1002/1099-1395(200007)13:7<388::aid-poc278>3.0.co;2-h

文献信息

• 1015. Thiohydantoins. Part II. Alkaline hydrolyses
  作者：J. T. Edward、S. Nielsen

  DOI：10.1039/jr9570005080

  日期：——
• Solid-state reactivity of the hydrazine-hydroquinone complex
  作者：Gerd Kaupp、Jens Schmeyers

  DOI：10.1002/1099-1395(200007)13:7<388::aid-poc278>3.0.co;2-h

  日期：2000.7

  The solid-state reactivities of the hydrazine-hydroquinone 1:1 complex and of hydrazine hydrochloride with solid aldehydes, ketones, carboxylic acids, thiohydantoin and 4-nitrophenyl isothiocyanate were investigated. Only the hydrazine complex provides quantitative additions, condensations, ring openings and ring closures. The solid-state mechanisms were investigated by atomic force microscopy (AFM) and the Ear-reaching anisotropic molecular movements are correlated with the crystal packing, both on the hydrazine complex surface and on the surface of two benzaldehydes. The hydrazine moves into the aldehyde crystals for chemical reaction without melting. Characteristic surface features are created by the common phase rebuilding and phase transformation on both the hydrazine-donating and -accepting crystals. Copyright (C) 2000 John Wiley & Sons, Ltd. Additional material for this paper is available from the epoc website at http://www.wiley.com/epoc.

表征谱图