3-iodo-1-methoxy-1-phenylpropane | 1309576-83-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-iodo-1-methoxy-1-phenylpropane
• 英文别名: Benzene, (3-iodo-1-methoxypropyl)-；(3-iodo-1-methoxypropyl)benzene
• CAS: 1309576-83-7
• 化学式: C₁₀H₁₃IO
• 分子量: 276.117
• InChiKey: UZMKCHHXIXWOBP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  甲醇 、 环丙基苯 在 potassium dichloroiodate 作用下， 以 氯仿 为溶剂， 以40%的产率得到3-iodo-1-methoxy-1-phenylpropane
  参考文献：
  名称：

  Reactions of cyclopropanes with potassium dihaloiodates

  摘要：

  Reactions of potassium dihaloiodates with arylcyclopropanes and polycyclic compounds containing a cyclopropane fragment characterized by different degrees of strain lead to formation of mixed 1,3-halogenation products. If iodohalogenation should give rise to products having a iodine atom in the benzylic position, 1,3-dichloro or 1,3-dibromo derivatives are formed. Iodohalogenation of exo-tricyclo[3.2.1.0(2,4)]octane is stereoselective and is accompanied by Wagner-Meerwein rearrangement.

  DOI：

  10.1134/s1070428011030031

文献信息

• Reactions of cyclopropanes with potassium dihaloiodates
  作者：N. V. Zyk、A. Yu. Gavrilova、O. B. Bondarenko、O. A. Mukhina、V. N. Tikhanushkina

  DOI：10.1134/s1070428011030031

  日期：2011.3

  Reactions of potassium dihaloiodates with arylcyclopropanes and polycyclic compounds containing a cyclopropane fragment characterized by different degrees of strain lead to formation of mixed 1,3-halogenation products. If iodohalogenation should give rise to products having a iodine atom in the benzylic position, 1,3-dichloro or 1,3-dibromo derivatives are formed. Iodohalogenation of exo-tricyclo[3.2.1.0(2,4)]octane is stereoselective and is accompanied by Wagner-Meerwein rearrangement.