(E)-S-styryl ethanethioate | 61363-83-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (E)-S-styryl ethanethioate
• 英文别名: S-[(E)-2-phenylethenyl] ethanethioate
• CAS: 61363-83-5
• 化学式: C₁₀H₁₀OS
• 分子量: 178.255
• InChiKey: HEIVVOSJJRIBAI-BQYQJAHWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  42.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  [(Z)-2-溴乙烯基]苯 、 potassium thioacetate 在 copper(l) iodide 、 1,10-菲罗啉 作用下， 以 甲苯 为溶剂， 反应 24.0h， 以25%的产率得到(E)-S-styryl ethanethioate
  参考文献：
  名称：

  不含过渡金属/配体催化剂和硫醇的烷基苯乙烯基硫化物的一锅法合成

  摘要：

  开发了一种新的苯乙烯基烷基硫化物一锅合成方案。该方法涉及通过硫代乙酸钾和烷基卤化物之间的亲核取代，然后进行碎裂，原位生成硫醇盐阴离子。这些硫醇盐阴离子与取代的 (E,Z)-β-苯乙烯基卤化物的进一步反应得到相应的硫化物，并以良好至极好的产率保留立体化学。该过程不需要金属催化剂，它在温和的条件下和短时间内进行，并且它没有恶臭和对空气敏感的烷基硫醇。

  DOI：

  10.1002/ejoc.201201163

文献信息

• NiNP@rGO Nanocomposites as Heterogeneous Catalysts for Thiocarboxylation Cross-Coupling Reactions
  作者：Marco Bandini、Lorenzo Lombardi、Raffaello Mazzaro、Massimo Gazzano、Alessandro Kovtun、Vittorio Morandi、Giulio Bertuzzi

  DOI：10.1055/a-1669-0944

  日期：2022.3

  and spectroscopic (ICP-EOS, XPS) analysis tools. The metal composite was effectively employed in the unprecedented heterogeneously Ni-assisted cross-coupling reaction of aryl/vinyl iodides and thiocarboxylates. A range of sulfur-containing aryl as well as vinyl derivatives (15 examples) was achieved in high yields (up to 82%), under mild reaction conditions, and with wide functional group tolerance

  制备了一种新型的无配体镍纳米颗粒支撑在 rGO 上（平均粒径分布 d = 9 ± 3 nm），并通过形态学 (Fe-SEM)、结构学 (P-XRD、HR-TEM) 和光谱学进行了充分表征(ICP-EOS, XPS) 分析工具。该金属复合物有效地用于芳基/乙烯基碘化物和硫代羧酸盐的前所未有的非均相 Ni 辅助交叉偶联反应。在温和的反应条件和广泛的官能团耐受性下，以高产率（高达 82%）获得了一系列含硫芳基和乙烯基衍生物（15 个实例）。
• An Easy-to-Machine Electrochemical Flow Microreactor: Efficient Synthesis of Isoindolinone and Flow Functionalization
  作者：Ana A. Folgueiras-Amador、Kai Philipps、Sébastien Guilbaud、Jarno Poelakker、Thomas Wirth

  DOI：10.1002/anie.201709717

  日期：2017.11.27

  Very little supporting electrolyte or none at all is needed in flow electrochemistry. Recycling and waste problems are eliminated as cyclization products are obtained in a fast and clean process.

  流动电化学中需要很少的辅助电解质或根本不需要。由于在快速，清洁的过程中获得了环化产品，因此消除了回收和废物问题。
• METHOD FOR PRODUCING FLUORINE-CONTAINING OLEFIN
  申请人：Asahi Glass Company, Limited

  公开号：US20180086684A1

  公开（公告）日：2018-03-29

  A method for producing at least one compound selected from the group consisting of a compound represented by the following formula (10), a compound represented by the following formula (11), a compound represented by the following formula (12), and a compound represented by the following formula (13), which the method containing reacting a compound represented by the following formula (2) with a compound represented by the following formula (7), in the presence of at least one compound selected from the group consisting of a compound represented by the following formula (1), a compound represented by the following formula (3), a compound represented by the following formula (4), a compound represented by the following formula (8), and a compound represented by the following formula (9).
• One-Pot Synthesis of Alkyl Styryl Sulfides Free from Transition Metal/Ligand Catalyst and Thiols
  作者：Adrián A. Heredia、Alicia B. Peñéñory

  DOI：10.1002/ejoc.201201163

  日期：2013.2

  developed. This methodology involves the in situ generation of thiolate anions by nucleophilic substitution between potassium thioacetate and alkyl halides followed by fragmentation. Further reactions of these thiolate anions with substituted (E,Z)-β-styryl halides gave the corresponding sulfides with retention of stereochemistry in good to excellent yields. This procedure does not require a metal catalyst

  开发了一种新的苯乙烯基烷基硫化物一锅合成方案。该方法涉及通过硫代乙酸钾和烷基卤化物之间的亲核取代，然后进行碎裂，原位生成硫醇盐阴离子。这些硫醇盐阴离子与取代的 (E,Z)-β-苯乙烯基卤化物的进一步反应得到相应的硫化物，并以良好至极好的产率保留立体化学。该过程不需要金属催化剂，它在温和的条件下和短时间内进行，并且它没有恶臭和对空气敏感的烷基硫醇。