salicylaldehyde-N-phenyl semicarbazone | 91991-03-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: salicylaldehyde-N-phenyl semicarbazone
• 英文别名: 2-hydroxybenzaldehyde N''-phenylsemicarbazone；1-[(E)-(2-Hydroxyphenyl)methyleneamino]-3-phenyl-urea；1-[(2-hydroxyphenyl)methylideneamino]-3-phenylurea
• CAS: 91991-03-6
• 化学式: C₁₄H₁₃N₃O₂
• 分子量: 255.276
• InChiKey: KJQAVFPMYZFAEU-UHFFFAOYSA-N

物化性质

• 熔点：
  188-189 °C
• 密度：
  1.21±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  73.7
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  RuH₂(CO)(PPh₃)₃ 、 salicylaldehyde-N-phenyl semicarbazone 以 苯 为溶剂， 以70%的产率得到
  参考文献：
  名称：

  SYNTHESIS, CHARACTERIZATION, AND BIOLOGICAL ACTIVITIES OF RUTHENIUM(II) CARBONYL COMPLEXES CONTAINING BIFUNCTIONAL TRIDENTATE SCHIFF BASES

  摘要：

  Ruthenium(II) carbonyl complexes have been synthesised by reacting [RuH2(CO)(PPh3)(3)] or [RuHCl(CO)(PPh3)(2)(Z)] (Z = PPh3, pyridine (py) or piperidine (pip)) with tridentate Schiff base ligands derived by condensing salicylaldehyde, o-vanillin or o-hydroxyacetophenone with N(4)-phenylsemi-carbazide. These complexes have been characterised by analytical, IR, electronic, H-1 NMR and P-31 NMR spectral studies. The complexes of the general formula [Ru(L) (CO)(PPh3)(Z)] (L = Schiff base anion; Z = PPh3, py or pip) tentatively have been assigned an octahedral structure. Some of the complexes have been tested for in vitro growth inhibitory activity against the bacteria Escherichia coli, Bacillus sp. and Pseudomonas sp.

  DOI：

  10.1081/sim-100105255

文献信息

• Synthesis, characterization and physicochemical properties of copper(II) complexes containing salicylaldehyde semicarbazone
  作者：Peng Foo Lee、Chang-Tong Yang、Daming Fan、Jagadese J Vittal、John D Ranford

  DOI：10.1016/s0277-5387(03)00402-9

  日期：2003.9

  Copper(II) complexes containing a series of salicylaldehyde semicarbazone ligands have been prepared and characterized by a range of physicochemical techniques. The X-ray structure of [Cu(HBnZ(2))Cl] . H2O (5) (where HBnz(2) is salicylaldehyde-N,N-dibenzyl semicarbazone) shows the complex is monomeric and the copper atom is four coordinated in a distorted square planar geometry. The ligand chelates the copper in a tridentate fashion through the imine N, carbonyl O and phenolato O with the fourth position being occupied by coordinated Cl. The compound [Cu(Ph-2) . H2O] (4) (where Ph-2 is salicylaldehyde-N,N-diphenyl semicarbazone) is also formulated as a monomer whereas all other complexes are assumed to have a side-by-side dimeric arrangement of the metal chelating with the phenolate bridging the Cu(II) centres. (C) 2003 Elsevier Ltd. All rights reserved.
• SYNTHESIS, CHARACTERIZATION, AND BIOLOGICAL ACTIVITIES OF RUTHENIUM(II) CARBONYL COMPLEXES CONTAINING BIFUNCTIONAL TRIDENTATE SCHIFF BASES
  作者：C. Jayabalakrishnan、K. Natarajan

  DOI：10.1081/sim-100105255

  日期：2001.6.30

  Ruthenium(II) carbonyl complexes have been synthesised by reacting [RuH2(CO)(PPh3)(3)] or [RuHCl(CO)(PPh3)(2)(Z)] (Z = PPh3, pyridine (py) or piperidine (pip)) with tridentate Schiff base ligands derived by condensing salicylaldehyde, o-vanillin or o-hydroxyacetophenone with N(4)-phenylsemi-carbazide. These complexes have been characterised by analytical, IR, electronic, H-1 NMR and P-31 NMR spectral studies. The complexes of the general formula [Ru(L) (CO)(PPh3)(Z)] (L = Schiff base anion; Z = PPh3, py or pip) tentatively have been assigned an octahedral structure. Some of the complexes have been tested for in vitro growth inhibitory activity against the bacteria Escherichia coli, Bacillus sp. and Pseudomonas sp.