isopropyl 2-hydroxy-4-methyl-benzoate | 190188-19-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: isopropyl 2-hydroxy-4-methyl-benzoate
• 英文别名: Propan-2-yl 2-hydroxy-4-methylbenzoate
• CAS: 190188-19-3
• 化学式: C₁₁H₁₄O₃
• mdl: MFCD21101263
• 分子量: 194.23
• InChiKey: LNMQKYAMYFOJLB-UHFFFAOYSA-N

物化性质

• 沸点：
  269.7±20.0 °C(Predicted)
• 密度：
  1.107±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.363
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4-甲基水杨酸 在 碳酸氢钠 作用下， 以 盐酸 、 异丙醇 为溶剂， 生成 isopropyl 2-hydroxy-4-methyl-benzoate
  参考文献：
  名称：

  Method for preparing scenting compositions and scented products, and resulting products

  摘要：

  本发明涉及一种用于生产香精组合物的方法，以及香精产品和由此获得的产品。更具体地说，本发明涉及一种用于生产香精组合物、香精产品和香水用物质的方法，其特点在于包含一种对气味具有影响的活性成分，即一定量的烷基水杨酸酯。

  公开号：

  US06458757B1

文献信息

• PROCEDE D'OBTENTION DE COMPOSITIONS PARFUMANTES ET DE PRODUITS PARFUMES ET PRODUITS AINSI OBTENUS
  申请人：RHODIA CHIMIE

  公开号：EP0876325B1

  公开（公告）日：2002-01-09
• COMPOUNDS AND COMPOSITIONS FOR USE IN THE TREATMENT AND PREVENTION OF CANCER AND PRECANCEROUS CONDITIONS, INFLAMMATION-RELATED DISORDERS, PAIN AND FEVER
  申请人：Medicon Pharmaceuticals, Inc.

  公开号：US20140121185A1

  公开（公告）日：2014-05-01

  Novel compounds and pharmaceutical compositions thereof for the treatment and/or prevention of cancer and precancerous conditions, inflammation-related disorders, pain and fever.
• COMPOUNDS AND COMPOSITIONS FOR USE IN THE PREVENTION AND TREATMENT OF INFLAMMATION-RELATED DISORDERS, PAIN AND FEVER, SKIN DISORDERS, CANCER AND PRECANCEROUS CONDITIONS THEREOF
  申请人：Medicon Pharmaceuticals, Inc.

  公开号：US20140315834A1

  公开（公告）日：2014-10-23

  The present invention provides novel compounds and pharmaceutical compositions for the prevention and/or treatment of cancer and precancerous conditions thereof, for the treatment of pain and fever, for the treatment of skin disorders, and for treating and/or preventing inflammation-related diseases and/or cardiovascular diseases. The compounds of the invention also have analgesic properties and anti-platelet properties. The compounds of the invention may be provided to animals, including mammals and humans, by administering a suitable pharmaceutical dose in a suitable pharmaceutical dosage form. The compounds of the invention have improved efficacy and safety, including higher potency and/or fewer or less severe side effects, than conventional therapies. The compounds of the invention comprise a biologically active moiety or portion (A) that has, or is modified to have at least one carboxyl group. The moiety A is preferably an aliphatic, aromatic or alkylaryl group, preferably derived from a non-steroidal anti-inflammatory drug or NSAID (A). The moiety A is bound to a linker moiety (B) via the carboxyl of group A and a linking atom that is selected from oxygen, nitrogen, and sulphur, to form a carboxylic ester, and amide, or a thioester, bond (X 1 ) between groups A and B. Moiety B is a single bond, an aliphatic group, a substituted benzene, or an alkylene substituted hydrocarbon chain, which in turn is bound to functional moiety Z, which facilitates access of the compound into cells. The moiety Z can comprise, for example, a phosphorous-containing group, a nitrogen-containing group, or a folic acid residue.
• US6458757B1
  申请人：——

  公开号：US6458757B1

  公开（公告）日：2002-10-01
• Method for preparing scenting compositions and scented products, and resulting products
  申请人：Chimie Rhodia

  公开号：US06458757B1

  公开（公告）日：2002-10-01

  The present invention relates to a process for the production of perfuming compositions, to perfumed products, and to products obtained therefrom. More specifically, the present invention concerns a process for the production of perfuming compositions, perfumed products and substances for perfumery characterized in that they comprise, as an active ingredient with an influence on the scent, an effective quantity of an alkylsalicylic acid ester.

  本发明涉及一种用于生产香精组合物的方法，以及香精产品和由此获得的产品。更具体地说，本发明涉及一种用于生产香精组合物、香精产品和香水用物质的方法，其特点在于包含一种对气味具有影响的活性成分，即一定量的烷基水杨酸酯。