(4-Methylphenyl)-(2,4,5-trimethoxyphenyl)methanone | 1061330-58-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (4-Methylphenyl)-(2,4,5-trimethoxyphenyl)methanone
• CAS: 1061330-58-2
• 化学式: C₁₇H₁₈O₄
• 分子量: 286.328
• InChiKey: UDLUTMVLRLXEAB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  21
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (4-Methylphenyl)-(2,4,5-trimethoxyphenyl)methanone 在 三溴化硼 作用下， 以 二氯甲烷 为溶剂， 以47%的产率得到(4-Methylphenyl)-(2,4,5-trihydroxyphenyl)methanone
  参考文献：
  名称：

  Design and synthesis of regioisomerically pure unsymmetrical xanthene derivatives for staining live cells and their photochemical properties

  摘要：

  We have demonstrated the synthesis of regioisomerically pure unsymmetrical xanthene derivatives consisting of three units which can be independently modified to control their physical properties. The photochemical properties of the synthetic unsymmetrical xanthene derivatives were investigated in solution by UV-vis absorption and fluorescence measurements, and their cell imaging properties were examined by confocal laser-scanning microscopy. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2008.06.065
• 作为产物：
  描述：

  1,2,4-三甲氧基苯 、 对甲基苯甲酰氯 在 aluminum (III) chloride 作用下， 以 二氯甲烷 为溶剂， 反应 2.0h， 以76%的产率得到(4-Methylphenyl)-(2,4,5-trimethoxyphenyl)methanone
  参考文献：
  名称：

  Design and synthesis of regioisomerically pure unsymmetrical xanthene derivatives for staining live cells and their photochemical properties

  摘要：

  We have demonstrated the synthesis of regioisomerically pure unsymmetrical xanthene derivatives consisting of three units which can be independently modified to control their physical properties. The photochemical properties of the synthetic unsymmetrical xanthene derivatives were investigated in solution by UV-vis absorption and fluorescence measurements, and their cell imaging properties were examined by confocal laser-scanning microscopy. (c) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2008.06.065

文献信息

• Design and synthesis of regioisomerically pure unsymmetrical xanthene derivatives for staining live cells and their photochemical properties
  作者：Shinichiro Kamino、Hayato Ichikawa、Shun-ichi Wada、Yuka Horio、Yoshihide Usami、Takako Yamaguchi、Toshiki Koda、Aki Harada、Kazusa Shimanuki、Masao Arimoto、Mitsunobu Doi、Yoshikazu Fujita

  DOI：10.1016/j.bmcl.2008.06.065

  日期：2008.8

  We have demonstrated the synthesis of regioisomerically pure unsymmetrical xanthene derivatives consisting of three units which can be independently modified to control their physical properties. The photochemical properties of the synthetic unsymmetrical xanthene derivatives were investigated in solution by UV-vis absorption and fluorescence measurements, and their cell imaging properties were examined by confocal laser-scanning microscopy. (c) 2008 Elsevier Ltd. All rights reserved.