2-chloro-5,β-dinitro-styrene | 15851-93-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-chloro-5,β-dinitro-styrene
• 英文别名: 2-Chlor-5,β-dinitro-styrol；2-Chlor-5-nitro-1-(β-nitrovinyl)-benzol；2-Chlor-β,5-dinitro-styrol；2-Chloro-beta,5-dinitrostyrene；1-chloro-4-nitro-2-(2-nitroethenyl)benzene
• CAS: 15851-93-1
• 化学式: C₈H₅ClN₂O₄
• 分子量: 228.592
• InChiKey: DEZMGZNWZYGVKZ-UHFFFAOYSA-N

物化性质

• 熔点：
  142 °C
• 沸点：
  376.4±32.0 °C(Predicted)
• 密度：
  1.519±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  91.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-chloro-5,β-dinitro-styrene 在 氨 、 苯 作用下， 生成 bis-[1-(2-chloro-5-nitro-phenyl)-2-nitro-ethyl]-amine
  参考文献：
  名称：

  The Action of Aromatic Amines on 4-Nitro-2-chloronitrostyrene

  摘要：

  DOI：

  10.1021/ja01279a006
• 作为产物：
  描述：

  1-chloro-2-(2-nitrovinyl)benzene 生成 2-chloro-5,β-dinitro-styrene
  参考文献：
  名称：

  Aromatic Amines and 3-Nitro-6-bromonitrostyrene

  摘要：

  DOI：

  10.1021/ja01265a113

文献信息

• Dithiocarbamate ester bactericides and fungicides
  申请人：American Cyanamid Company

  公开号：US04148795A1

  公开（公告）日：1979-04-10

  The present invention relates to certain novel dithiocarbamate esters, methods for their synthesis and their use as bactericidal and fungicidal agents.

  本发明涉及某些新型二硫代氨基甲酸酯，其合成方法及其作为杀菌剂和杀真菌剂的用途。
• Sugar amide-pyrrolidine catalyst for the asymmetric Michael addition of ketones to nitroolefins
  作者：Togapur Pavan Kumar、Sirinyam Venugopal Balaji

  DOI：10.1016/j.tetasy.2014.02.003

  日期：2014.3

  New sugar amide-pyrrolidine derivatives possessing the furano form of the carbohydrate template were designed and developed as efficient and stereoselective organocatalysts for asymmetric Michael additions of ketones to nitroolefins at room temperature. Good yields and high selectivities were achieved with catalyst 2 under solvent-free and additive-free reaction conditions. (C) 2014 Elsevier Ltd. All rights reserved.
• Antifungal Activity of a Series of Substituted [(α-Nitroalkyl)benzylthio]alkylamines¹
  作者：Robert C. Tweit、R. D. Muir、Seth Mizuba、Webster R. Crowley

  DOI：10.1021/jm00327a019

  日期：1965.5
• Pyrrolidine-oxyimides: new chiral catalysts for enantioselective Michael addition of ketones to nitroolefins in water
  作者：Togapur Pavan Kumar、Laghuvarapu Radhika、Kothapalli Haribabu、Veerjala Naveen Kumar

  DOI：10.1016/j.tetasy.2014.10.014

  日期：2014.12

  A new class of proline based organocatalysts 'pyrrolidine-oxyimides' were designed and synthesized from L-proline and hydroxyimides by employing a simple reaction protocol. These catalysts were found to be efficient in promoting asymmetric Michael additions of ketones to nitroolefins at room temperature. Good yields and high selectivities were obtained with catalyst 1a under additive-free conditions employing water as the reaction medium. (C) 2014 Elsevier Ltd. All rights reserved.
• Cascade Oxa-Michael–Henry Reaction of Salicylaldehydes with Nitrostyrenes via Ball Milling: A Solvent-Free Synthesis of 3-Nitro-2H-chromenes
  作者：Chun-Man Jia、Qi Zhang、Shui-Xiang Liu、Bo-Yuan Yao、Xiang-Long Chen

  DOI：10.1055/s-0035-1560964

  日期：——

  Cascade oxa-Michael-Henry reactions of salicylaldehyde derivatives with beta-nitrostyrenes catalyzed by potassium carbonate via solvent-free ball milling are demonstrated. The corresponding 3-nitro-2H-chromene products were obtained in moderate to excellent yields. This method offers significant advantages, particularly in terms of high yields, short reaction times and mild conditions.