1-Chloro-2-[1-(4-fluorophenyl)ethenyl]benzene | 85000-55-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Chloro-2-[1-(4-fluorophenyl)ethenyl]benzene
• CAS: 85000-55-1
• 化学式: C₁₄H₁₀ClF
• 分子量: 232.68
• InChiKey: NAFHYJIIUKQSRU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-chloro-2-[2-chloro-1-(4-fluorophenyl)ethyl]benzene 、 sodium ethanolate 生成 1-Chloro-2-[1-(4-fluorophenyl)ethenyl]benzene
  参考文献：
  名称：

  BALON, YA. G.;SHULMAN, M. D., YKP. XIM. ZH., 57,(1991) N, S. 191-195

  摘要：

  DOI：

文献信息

• Process for the preparation of 1,1-bis phenyl-2-haloalkan-1-ols
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0065354A1

  公开（公告）日：1982-11-24

  Halohydrins of the formula: wherein R and R1, which may be the same or different, are hydrogen or alkyl; X, Y and Z are each independently hydrogen, fluorine or chlorine and A is chlorine or bromine, are prepared by reacting a tertiary alcohol of the formula or a substituted alkene of the formula with chlorine, bromine, hypochlorous acid or hypobromous acid in an aqueous medium. Preferably the aqueous medium is a mixture of water and an amide solvent selected from dimethyl formamide, diethyl formamide and dimethyl acetamide and the reaction is carried out in the presence of hydrogen peroxide. The halohydrins are useful intermediates for fungicides.

  式中的 R 和 R1（可以相同或不同）是氢或烷基；X、Y 和 Z 各自独立地是氢、氟或氯，A 是氯或溴。 水介质最好是水和选自二甲基甲酰胺、二乙基甲酰胺和二甲基乙酰胺的酰胺溶剂的混合物，反应在过氧化氢存在下进行。 卤化烃是杀真菌剂的有用中间体。
• 1,1-Diphenylalkenes and a process for their preparation
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0066943A1

  公开（公告）日：1982-12-15

  These compounds have the general formula: wherein R and R', which may be the same or different, are hydrogen or alkyl, preferably C1-C4 alkyl, and X, Y and Z are each independently hydrogen, chlorine or fluorine, provided that when R, R' and Z are hydrogen, X and Y are not both hydrogen or both fluorine, and are prepared by dehydrating an alcohol of the formula: by, for example, heating the alcohol in the presence of a catalytic amount of a strong acid such as p-toluenesulphonic acid and preferably in the presence of an inert solvent. The compounds are intermediates for the preparation of fungicidal compounds.

  这些化合物的通式为：其中 R 和 R'（可以相同或不同）为氢或烷基，最好是 C1-C4 烷基，X、Y 和 Z 各自独立地为氢、氯或氟，但当 R、R'和 Z 均为氢时，X 和 Y 不能同时为氢或同时为氟。 这些化合物是制备杀菌化合物的中间体。
• 1,1-Bis phenylalkan-1-ols and processes for their preparation
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0065814B1

  公开（公告）日：1985-08-14
• US4898997A
  申请人：——

  公开号：US4898997A

  公开（公告）日：1990-02-06