2,2,2-Trifluoro-1-phenyl-1-(trifluoromethyl)ethyl methacrylate | 130540-87-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2,2-Trifluoro-1-phenyl-1-(trifluoromethyl)ethyl methacrylate
• 英文别名: (1,1,1,3,3,3-hexafluoro-2-phenylpropan-2-yl) 2-methylprop-2-enoate
• CAS: 130540-87-3
• 化学式: C₁₃H₁₀F₆O₂
• 分子量: 312.21
• InChiKey: SFYAZQDOFPKNOH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  1,1,1,3,3,3-六氟代-2-苯基-2-丙醇 、 甲基丙烯酰氯 生成 2,2,2-Trifluoro-1-phenyl-1-(trifluoromethyl)ethyl methacrylate
  参考文献：
  名称：

  VASIMI, AKIRA;JOSIDA, MASAO;KIMURA, KAORU

  摘要：

  DOI：

文献信息

• LENS FOR EYE AND METHOD FOR MARKING THEREOF
  申请人：Menicon Co., Ltd.

  公开号：EP1566684A1

  公开（公告）日：2005-08-24

  It is an object of the present invention to provide an ophthalmic lens characterized in that it is capable of developing a color at a position where a light is irradiated, and to provide a marking method of the ophthalmic lens. It is another object of the present invention to provide an ophthalmic lens, which can form a clear and easily readable mark, without causing problems such as discoloration of the mark, caused by cleaning of the lens by rubbing, or deterioration of the mechanical strength of the lens, and to provide a marking method of the ophthalmic lens. The ophthalmic lens of the present invention is obtained by a polymerization of a polymerizable composition of monomers, which contains an alkyl (meth)acrylate as an essential polymerizable component, and this polymerization is carried out while the rhodamine derivative is existed in the composition.

  本发明的一个目的是提供一种眼科镜片，其特征在于它能够在光线照射的位置显色，并提供眼科镜片的标记方法。本发明的另一个目的是提供一种眼科镜片，它能形成清晰易读的标记，而不会产生诸如因摩擦清洁镜片而导致标记褪色或镜片机械强度下降等问题，并提供一种眼科镜片的标记方法。本发明的眼科镜片是通过聚合单体的可聚合组合物获得的，该组合物含有烷基（甲基）丙烯酸酯作为重要的可聚合成分，聚合时组合物中存在罗丹明衍生物。
• CONTACT LENS MATERIAL
  申请人：Menicon Co., Ltd.

  公开号：EP1696257A1

  公开（公告）日：2006-08-30

  A contact lens material which has high oxygen permeability and mechanical strength, and extremely small in an amount of remaining unpolymerized monomers, at the same time, low in a water absorption ratio and excellent in shape stability of a lens is provided. The contact lens material comprises a copolymer obtained by polymerizing copolymer components containing a particular silicone-containing monomer, wherein the total residual amount of unpolymerized monomer components remaining in the copolymer based on the copolymer is at most 3.5 % by weight, an oxygen permeability coefficient of the copolymer is at least 130 × 10-11 (cm2/sec)·(mLO2)/(mL·mmHg), and a water absorption ratio of the copolymer is at most 0.3 % by weight.

  一种隐形眼镜材料具有较高的透氧性和机械强度，剩余的未聚合单体量极少，同时吸水率低，镜片形状稳定性极佳。该隐形眼镜材料包括一种通过聚合含有特定含硅单体的共聚物成分而获得的共聚物，其中基于共聚物的未聚合单体成分的总残留量最多为 3.5%（按重量计），共聚物的透氧系数至少为 130 × 10-11 (cm2/sec)-(mLO2)/(mL-mmHg) ，共聚物的吸水率最多为 0.3%（按重量计）。
• OPHTHALMIC LENS
  申请人：Menicon Co., Ltd.

  公开号：EP2453293A1

  公开（公告）日：2012-05-16

  The present invention is directed to an ophthalmic lens integrally formed with a hydrogel, the hydrogel including a copolymer obtained from a composition containing (A) an ionic compound including a cation having a polymerizable functional group, and a fluorine-containing anion (hereinafter, referred to as (A) ionic compound), and (B) a hydrophilic compound having a polymerizable functional group.

  本发明涉及一种与水凝胶一体成型的眼科晶状体，该水凝胶包括一种共聚物，该共聚物由含有以下成分的组合物制成：(A) 离子化合物，包括具有可聚合官能团的阳离子和含氟阴离子（以下简称(A)离子化合物）；(B) 具有可聚合官能团的亲水化合物。
• Intraocular lens
  申请人：MENICON CO., LTD.

  公开号：US10716875B2

  公开（公告）日：2020-07-21

  An intraocular lens includes a polymeric lens material formed from a polymerizable composition. The polymerizable composition includes: (a) a single aromatic acrylate monomer which is an aromatic-ring containing acrylate; (b) an alkoxyalkyl methacrylate monomer having an alkoxyalkyl group with 4 or less carbon atoms; (c) an alkyl acrylate monomer having an alkyl group with 1 to 20 carbon atoms; (d) a hydrophilic monomer; and (e) a crosslinkable monomer.

  眼内透镜包括由可聚合组合物形成的聚合透镜材料。可聚合组合物包括(a) 单个芳香族丙烯酸酯单体，该单体为含芳香环的丙烯酸酯；(b) 烷氧基烷基甲基丙烯酸酯单体，该单体具有 4 个或更少的碳原子的烷氧基烷基；(c) 烷基丙烯酸酯单体，该单体具有 1 至 20 个碳原子的烷基；(d) 亲水单体；以及 (e) 可交联单体。
• Ocular lens material and process for producing the same
  申请人：Menicon Co., Ltd.

  公开号：US20040054106A1

  公开（公告）日：2004-03-18

  An ocular lens material comprising a siloxane-containing polymer obtained by polymerizing a monomer mixture containing (A) a siloxane macromonomer having at least two active unsaturated groups and a number average molecular weight of 2,000 to 100,000; and (B) a vinyl ester of lower fatty acid as essential components. An ocular lens material comprising a polymer obtained by saponification of the siloxane-containing polymer. Processes for producing the ocular lens materials. The ocular lens materials are excellent not only in lipid-stain resistance, wettability and oxygen permeability, but also in flexibility, particularly, shape recovery at the same time.

  一种眼科晶状体材料，包含一种含硅氧烷聚合物，该聚合物通过聚合单体混合物而得，该单体混合物包含(A)硅氧烷大单体，该硅氧烷大单体具有至少两个活性不饱和基团，且平均分子量在 2,000 至 100,000 之间；以及(B)低级脂肪酸乙烯基酯作为基本成分。一种眼晶状体材料，包含一种通过皂化含硅氧烷聚合物而获得的聚合物。生产眼科晶状体材料的工艺。该眼科晶状体材料不仅在抗脂质污渍性、润湿性和透氧性方面表现出色，而且在柔韧性，特别是形状恢复方面也很出色。