((2-methylbutoxy)methyl)benzene | 69205-11-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: ((2-methylbutoxy)methyl)benzene
• 英文别名: benzyl-(2-methyl-butyl)-ether；Benzyl-(2-methyl-butyl)-aether；[(2-methylbutoxy)methyl]benzene；2-Methylbutyl benzyl ether；2-methylbutoxymethylbenzene
• CAS: 69205-11-4
• 化学式: C₁₂H₁₈O
• 分子量: 178.274
• InChiKey: YOANEDOLERYMCY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  [(RS)-2-methylbut-3-enyloxymethyl]benzene 在 air 、 一水合肼 作用下， 以 乙醇 为溶剂， 反应 4.0h， 以99%的产率得到((2-methylbutoxy)methyl)benzene
  参考文献：
  名称：

  使用有机催化生成的二酰亚胺还原碳-碳双键。

  摘要：

  已经开发出一种有效的方法来用二酰亚胺还原碳-水双键，二酰亚胺是由水合肼原位催化生成的。所用的催化剂是从核黄素（维生素B（2））一步制备而成的。反应是在空气中进行的，当金属催化的加氢反应有问题时，它是一种有价值的替代方法。

  DOI：

  10.1021/jo801588d

文献信息

• TRICYCLIC BORON COMPOUNDS FOR ANTIMICROBIAL THERAPY
  申请人：MICURX PHARMACEUTICALS, INC.

  公开号：US20130165411A1

  公开（公告）日：2013-06-27

  Provided herein are antimicrobial tricyclic boron compounds of the following formula I: or pharmaceutically acceptable salts, complexes, or tautomers thereof that are antibacterial agents, pharmaceutical compositions containing them, methods for their use, and methods for preparing these compounds.

  本文提供以下式子I的抗微生物三环硼化合物，或其药学上可接受的盐、络合物或互变异构体，它们是抗菌剂，含有它们的制药组合物，使用它们的方法，以及制备这些化合物的方法。
• Derivatives of 4-piperazin-1-yl-4-benzo[b]thiophene suitable for the treatment of cns disorders
  申请人：Yamashita Hiroshi

  公开号：US20090264404A1

  公开（公告）日：2009-10-22

  A heterocyclic compound or a salt thereof represented by the formula (1): where R 2 represents a hydrogen atom or a lower alkyl group; A represents a lower alkylene group or lower alkenylene group; and R 1 represents an aromatic group or a heterocyclic group. The compound of the present invention has a wide treatment spectrum for mental disorders including central nervous system disorders, no side effects and high safety.

  一种杂环化合物或其盐，其化学式为（1）：其中R2代表氢原子或较低的烷基基团；A代表较低的烷基烯基基团；R1代表芳香族基团或杂环基团。本发明的化合物具有广泛的治疗精神障碍的谱，包括中枢神经系统障碍，无副作用且安全性高。
• MODIFIED BIO-RELATED SUBSTANCE, PROCESS FOR PRODUCING THE SAME, AND INTERMEDIATE
  申请人：Nakamoto Ken-ichiro

  公开号：US20110082277A1

  公开（公告）日：2011-04-07

  A modified bio-related substance, wherein at least one poly(alkylene glycol)oxy group represented by the following formula (1) is combined in a molecule: wherein R is a hydrocarbon group having 1 to 24 carbon atoms, OA 1 and OA 2 are each an oxyalkylene group having 2 to 4 carbon atoms, the groups represented by R are the same or different from each other in one molecule, and the groups represented by OA 2 are the same or different from each other in one molecule, n and m are each average number of moles of the oxyalkylene group added, n represents 0 to 1000, and m represents 10 to 1000.

  一种改性的生物相关物质，其中至少一个由以下公式（1）表示的聚（烷基氧基乙烯）氧基团结合在分子中：其中R是具有1至24个碳原子的碳氢基团，OA1和OA2分别是具有2至4个碳原子的氧烷基团，由R表示的基团在一个分子中相同或不同，由OA2表示的基团在一个分子中相同或不同，n和m分别是添加的氧烷基团的平均摩尔数，n表示0至1000，m表示10至1000。
• DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZO[B]THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS
  申请人：YAMASHITA Hiroshi

  公开号：US20120028920A1

  公开（公告）日：2012-02-02

  A heterocyclic compound or a salt thereof represented by the formula (1): where R 2 represents a hydrogen atom or a lower alkyl group; A represents a lower alkylene group or lower alkenylene group; and R 1 represents an aromatic group or a heterocyclic group. The compound of the present invention has a wide treatment spectrum for mental disorders including central nervous system disorders, no side effects and high safety.

  一种由式（1）所表示的杂环化合物或其盐：其中R2代表氢原子或较低的烷基基团；A代表较低的烷基烯基基团；R1代表芳香基团或杂环基团。本发明的化合物具有广泛的治疗精神障碍的光谱，包括中枢神经系统障碍，无副作用且安全性高。
• BiBr3, an efficient catalyst for the benzylation of alcohols: 2-phenyl-2-propyl, a new benzyl-type protecting group
  作者：Bernard Boyer、El-Mehdi Keramane、Jean-Pierre Roque、André A Pavia

  DOI：10.1016/s0040-4039(00)00304-x

  日期：2000.4

  The benzylation of aliphatic alcohols with various benzylic alcohols has been achieved in the presence of BiBr3 under mild conditions. 2-Phenylpropan-2-ol proved to be the most efficient and can be considered as a novel protecting group. (C) 2000 Elsevier Science Ltd. All rights reserved.