N-(4-chlorophenyl)-N'-(2-sulfanylphenyl)benzenecarboximidamide | 1131897-05-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯硫酚类
• 英文名称: N-(4-chlorophenyl)-N'-(2-sulfanylphenyl)benzenecarboximidamide
• CAS: 1131897-05-6
• 化学式: C₁₉H₁₅ClN₂S
• 分子量: 338.861
• InChiKey: LTWALFLUESDBFZ-UHFFFAOYSA-N

物化性质

• 熔点：
  121-124 °C(Solvent: Ethanol)
• 沸点：
  515.1±50.0 °C(predicted)
• 密度：
  1.20±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  25.4
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N-(4-氯-苯基)-苯酰胺 、 2-氨基苯硫醇 以 乙醇 为溶剂， 反应 4.0h， 以80%的产率得到N-(4-chlorophenyl)-N'-(2-sulfanylphenyl)benzenecarboximidamide
  参考文献：
  名称：

  Microwave-assisted synthesis, characterization and biological activities of organotin (IV) complexes with some thio Schiff bases

  摘要：

  Microwave-assisted synthesis and characterization of the organotin (IV) complexes are reported. Trigonal bipyramidal and octahedral complexes of tin (IV) have been synthesized by the reaction of dimethyltin (IV) dichloride with 4-nitrobenzanilide-S-benzyldithiocarbazate ((LH)-H-1), 4-chlorobenzanilide-S-benzyldithiocarbazate ((LH)-H-2), 4-nitrobenzanilidebenzothiazoline ((LH)-H-3) and 4-chlorobenzanilidebenzothiazoline ((LH)-H-4). The complexes so formed were characterized by elemental analysis, conductance measurements, molecular weight determinations and spectral data viz. IR, UV-Visible, H-1 and C-13 NMR. The anti-microbial activities of the ligands and their corresponding organotin (IV) complexes have been screened against various strains of bacteria and fungi. Antifertility activity against male albino rats has also been reported. (c) 2008 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2008.09.017

文献信息

• Microwave-assisted synthesis, characterization and biological activities of organotin (IV) complexes with some thio Schiff bases
  作者：Ran Vir Singh、Pratibha Chaudhary、Shikha Chauhan、Monika Swami

  DOI：10.1016/j.saa.2008.09.017

  日期：2009.3

  Microwave-assisted synthesis and characterization of the organotin (IV) complexes are reported. Trigonal bipyramidal and octahedral complexes of tin (IV) have been synthesized by the reaction of dimethyltin (IV) dichloride with 4-nitrobenzanilide-S-benzyldithiocarbazate ((LH)-H-1), 4-chlorobenzanilide-S-benzyldithiocarbazate ((LH)-H-2), 4-nitrobenzanilidebenzothiazoline ((LH)-H-3) and 4-chlorobenzanilidebenzothiazoline ((LH)-H-4). The complexes so formed were characterized by elemental analysis, conductance measurements, molecular weight determinations and spectral data viz. IR, UV-Visible, H-1 and C-13 NMR. The anti-microbial activities of the ligands and their corresponding organotin (IV) complexes have been screened against various strains of bacteria and fungi. Antifertility activity against male albino rats has also been reported. (c) 2008 Elsevier B.V. All rights reserved.