(pyridin-2-yl)methyl methacrylate | 30079-71-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: (pyridin-2-yl)methyl methacrylate
• 英文别名: methacrylic acid-[2]pyridylmethyl ester；Methacrylsaeure-[2]pyridylmethylester；2-Methacryloyloxymethylpyridine；pyridin-2-ylmethyl 2-methylprop-2-enoate
• CAS: 30079-71-1
• 化学式: C₁₀H₁₁NO₂
• 分子量: 177.203
• InChiKey: IGFJORFHZLIQAI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  39.2
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-吡啶甲醇 、 甲基丙烯酰氯 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 1.0h， 生成 (pyridin-2-yl)methyl methacrylate
  参考文献：
  名称：

  “Inverse Polyampholyte” Hydrogels from Double-Cationic Hydrogels: Synthesis by RAFT Polymerization and Characterization

  摘要：

  We present two novel, homologous, pyridine-based monomers, 2-(pyridin-2-yl)ethyl methacrylate (PyEMA) and (pyridin-2-yl)methyl methacrylate (PyMMA), which, despite their structural similarity, the former can be readily. thermolyzed to methacrylic acid, while the latter remains intact under the same conditions. This was most dramatically demonstrated in the present work, where PyEMA and PyMMA were randomly terpolymerized with a dimethacrylate cross-linker using reversible addition-fragmentation chain transfer polymerization to yield weakly double-cationic polyelectrolyte hydrogels of three different compositions which, upon thermal treatment, they were readily converted to polyampholyte hydrogels. While the parent double-cationic polyelectrolyte hydrogels exhibited a swelling response only to low-pH conditions, the daughter polyampholyte hydrogels presented swelling responses to both high- and low-pH conditions. Owing to the relative values of the effective pK(a)'s of the weakly acidic and weakly basic units, with the latter being lower than the former ("inverse polyampholyte" behavior), the swelling profiles of the daughter hydrogels were insensitive to polyampholyte composition.

  DOI：

  10.1021/ma500084c

文献信息

• THE PREPARATION OF SOME ESTERS OF METHACRYLIC ACID
  作者：JOGINDER LAL、RICHARD GREEN

  DOI：10.1021/jo01365a013

  日期：1955.8
• US5726218A
  申请人：——

  公开号：US5726218A

  公开（公告）日：1998-03-10
• “Inverse Polyampholyte” Hydrogels from Double-Cationic Hydrogels: Synthesis by RAFT Polymerization and Characterization
  作者：Kyriaki S. Pafiti、Marios Elladiou、Costas S. Patrickios

  DOI：10.1021/ma500084c

  日期：2014.3.11

  We present two novel, homologous, pyridine-based monomers, 2-(pyridin-2-yl)ethyl methacrylate (PyEMA) and (pyridin-2-yl)methyl methacrylate (PyMMA), which, despite their structural similarity, the former can be readily. thermolyzed to methacrylic acid, while the latter remains intact under the same conditions. This was most dramatically demonstrated in the present work, where PyEMA and PyMMA were randomly terpolymerized with a dimethacrylate cross-linker using reversible addition-fragmentation chain transfer polymerization to yield weakly double-cationic polyelectrolyte hydrogels of three different compositions which, upon thermal treatment, they were readily converted to polyampholyte hydrogels. While the parent double-cationic polyelectrolyte hydrogels exhibited a swelling response only to low-pH conditions, the daughter polyampholyte hydrogels presented swelling responses to both high- and low-pH conditions. Owing to the relative values of the effective pK(a)'s of the weakly acidic and weakly basic units, with the latter being lower than the former ("inverse polyampholyte" behavior), the swelling profiles of the daughter hydrogels were insensitive to polyampholyte composition.