N-(n-butyl)-4-(1H-phenanthro[9,10-d]imidazol-2-yl)benzamide | 1322759-55-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: N-(n-butyl)-4-(1H-phenanthro[9,10-d]imidazol-2-yl)benzamide
• 英文别名: N-butyl-4-(1H-phenanthro[9,10-d]imidazol-2-yl)benzamide
• CAS: 1322759-55-6
• 化学式: C₂₆H₂₃N₃O
• 分子量: 393.488
• InChiKey: PIJIUMRQBKDAKT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  57.8
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-(n-butyl)-4-(1H-phenanthro[9,10-d]imidazol-2-yl)benzamide 在 劳森试剂 作用下， 以 甲苯 为溶剂， 反应 12.0h， 以73%的产率得到N-(n-butyl)-4-(1H-phenanthro[9,10-d]imidazol-2-yl)thiobenzamide
  参考文献：
  名称：

  Phenanthroimidazole-based thiobenzamide as an effective sensor for highly selective detection of mercury(II)

  摘要：

  Based on highly selective and irreversible Hg2+-promoted desulfurization reaction, a new and simple phenanthroimidazole-type sensor was prepared and exhibited high selectivity towards Hg2+ ion over other metal ions, accompanied by transformation of a weakly fluorescent thioamide moiety (colorless) to a highly fluorescent amide one (blue), with a 136-fold increase in fluorescent intensity in aqueous solution with a pH span 2.57-9.12. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2013.03.083
• 作为产物：
  描述：

  N-(n-butyl)-4-(1H-phenanthro[9,10-d]imidazol-2-yl)thiobenzamide 在 汞 作用下， 以 乙腈 为溶剂， 生成 N-(n-butyl)-4-(1H-phenanthro[9,10-d]imidazol-2-yl)benzamide
  参考文献：
  名称：

  Phenanthroimidazole-based thiobenzamide as an effective sensor for highly selective detection of mercury(II)

  摘要：

  Based on highly selective and irreversible Hg2+-promoted desulfurization reaction, a new and simple phenanthroimidazole-type sensor was prepared and exhibited high selectivity towards Hg2+ ion over other metal ions, accompanied by transformation of a weakly fluorescent thioamide moiety (colorless) to a highly fluorescent amide one (blue), with a 136-fold increase in fluorescent intensity in aqueous solution with a pH span 2.57-9.12. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2013.03.083

文献信息

• Phenanthroimidazole-based thiobenzamide as an effective sensor for highly selective detection of mercury(II)
  作者：Yong Guo、Yuanyuan Yan、Xiaoyan Zhi、Chun Yang、Hui Xu

  DOI：10.1016/j.bmcl.2013.03.083

  日期：2013.6

  Based on highly selective and irreversible Hg2+-promoted desulfurization reaction, a new and simple phenanthroimidazole-type sensor was prepared and exhibited high selectivity towards Hg2+ ion over other metal ions, accompanied by transformation of a weakly fluorescent thioamide moiety (colorless) to a highly fluorescent amide one (blue), with a 136-fold increase in fluorescent intensity in aqueous solution with a pH span 2.57-9.12. (C) 2013 Elsevier Ltd. All rights reserved.