N-Furfuryl-ethylendiamin | 5700-58-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-Furfuryl-ethylendiamin
• 英文别名: N-(2-furylmethyl)ethylenediamine；N'-(furan-2-ylmethyl)ethane-1,2-diamine
• CAS: 5700-58-3
• 化学式: C₇H₁₂N₂O
• mdl: MFCD00520651
• 分子量: 140.185
• InChiKey: SDYAGGMEBLMHCR-UHFFFAOYSA-N

物化性质

• 沸点：
  103-103.5 °C(Press: 10 Torr)
• 密度：
  1.0470 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  51.2
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-Furfuryl-ethylendiamin 在 溴 、 sodium methylate 、 溶剂黄146 作用下， 以 甲醇 、 乙醇 、 乙腈 为溶剂， 反应 4.34h， 生成 (E)-2-[1-(2-furanylmethyl)-2-imidazolidinylidene]-2-nitroacetonitrile
  参考文献：
  名称：

  Design, synthesis, and bioactivity of cyanonitrovinyl neonicotinoids as potential insecticides

  摘要：

  A series of cyanonitrovinyl neonicotinoids were designed and synthesized via five steps in about 35% overall yields. All compounds were structurally characterized by (1)H nuclear magnetic resonance (NMR), (13)C NMR, infrared (IR), and high-resolution mass spectrometry (HRMS), and single-crystal X-ray diffraction analysis of 2-[1-[(6-chloropyridin-3-yl)methyl]-2-imidazolidinylidene]-2-nitroacetonitrile revealed that the double bond is (E)-configured. The preliminary agriculture bioassay indicated that one compound exhibited moderate insecticidal activity against pea aphid.

  DOI：

  10.1007/s00706-010-0375-4
• 作为产物：
  描述：

  糠基氯 、 乙二胺 以 乙腈 为溶剂， 生成 N-Furfuryl-ethylendiamin
  参考文献：
  名称：

  以咪唑啉为潜在杀菌剂的不对称二氟硼配合物的设计、合成和评价

  摘要：

  通过新的螯合配体（芳甲基-咪唑啉亚基）-吡啶-2-基-胺与三氟化硼乙醚化物的反应，合成了一系列与吡啶和咪唑啉的不对称二氟-硼（BF2）配合物。所有配体和 BF2 配合物均通过 IR、HRMS、1H、13C、11B 和 19F NMR 进行结构表征，表明咪唑啉氮和吡啶氮与硼中心的双齿络合。农业生物活性评价表明，一些 BF2 复合物表现出中等的杀真菌活性，大多数 BF2 复合物表现出比非 BF2 复合底物更高的活性。© 2010 Wiley Periodicals, Inc. 杂原子化学 20:418–424, 2009; 在线发表于 Wiley InterScience (www.interscience.wiley.com)。DOI 10.1002/hc.20567

  DOI：

  10.1002/hc.20567

文献信息

• PROTECTED MONOMER AND METHOD OF FINAL DEPROTECTION FOR RNA SYNTHESIS
  申请人：Dellinger Douglas J.

  公开号：US20100076183A1

  公开（公告）日：2010-03-25

  A nucleoside monomer that is protected by a thionocarbamate protecting group is provided, as well as a method for making a polynucleotide that uses the same. Also provided is a polynucleotide synthesis method that employs a diamine to deprotect a protected polynucleotide.

  提供了一种由硫代氨基甲酸酯保护基保护的核苷单体，以及使用该核苷单体制备多核苷酸的方法。还提供了一种利用二胺去保护受保护多核苷酸的多核苷酸合成方法。
• METHOD FOR PREPARING SILANE DERIVATIVES FROM FURAN DERIVATIVES IN PRESENCE OF BORANE CATALYST
  申请人：INSTITUTE FOR BASIC SCIENCE

  公开号：US20190263840A1

  公开（公告）日：2019-08-29

  The present invention relates to a method for preparing various silane derivatives by subjecting various furan derivatives to hydrosilylation in the presence of a borane catalyst. The method for preparing silane derivatives according to the present invention is a very efficient method for converting, into high value-added silane derivatives, various furan derivatives derived from biomass.

  本发明涉及一种通过在硼烷催化剂存在下将各种呋喃衍生物经过氢硅烷化反应制备各种硅烷衍生物的方法。根据本发明的制备硅烷衍生物的方法是一种非常高效的方法，可将生物质衍生的各种呋喃衍生物转化为高附加值的硅烷衍生物。
• Synthesis and selected properties of N-substituted pyrrolo[2,1-c]-1,3-diazacycloalkano[1,2-a]pyrazinones
  作者：G. V. Mokrov、A. M. Likhosherstov、V. P. Lezina、T. A. Gudasheva、I. S. Bushmarinov、M. Yu. Antipin

  DOI：10.1007/s11172-010-0230-0

  日期：2010.6

  The reactions of methyl α-(2-formyl-1H-pyrrol-1-yl)carboxylates with N-substituted aliphatic 1,2-, 1,3-, and 1,4-diamines afford new pyrrole-containing heterocyclic systems: 1,2,3,10b-tetrahydroimidazo[1,2-a]pyrrolo[2,1-c]pyrazin-5(6H)-ones, 1,3,4,11b-tetrahydro-2H-pyrrolo[2′,1′:3,4]pyrazino[1,2-a]pyrimidin-6(7H)-ones, and 1,2,3,4,5,12b-hexahydro-pyrrolo[2′,1′:3,4]pyrazino[1,2-a][1,3]diazepin-7(8H)-ones

  α-(2-甲酰基-1H-吡咯-1-基)羧酸甲酯与 N-取代的脂肪族 1,2-、1,3- 和 1,4-二胺反应生​​成新的含吡咯杂环系统：1 ,2,3,10b-四氢咪唑并[1,2-a]吡咯并[2,1-c]吡嗪-5(6H)-酮,1,3,4,11b-四氢-2H-吡咯并[2',1 ':3,4]吡嗪并[1,2-a]嘧啶-6(7H)-酮和1,2,3,4,5,12b-六氢吡咯并[2',1':3,4] pyrazino[1,2-a][1,3]diazepin-7(8H)-ones。研究了用不同试剂还原这些化合物。
• One step from nitro to oxime: a convenient preparation of unsaturated oximes by the reduction of the corresponding vinylnitro compounds
  作者：Kewei Wang、Xuhong Qian、Jingnan Cui

  DOI：10.1016/j.tet.2009.10.042

  日期：2009.12

  A series of novel unsaturated oximes were conveniently prepared from the corresponding vinylnitro compounds by reduction with SnCl2·2H2O. The structures of the oximes were characterized by 1H and 13C NMR, IR and HRMS, and X-ray crystallography analysis of 1-(6-chloro-pyridin-3-ylmethyl)-4,5-dihydro-1H-imidazole-2-carbaldehyde oxime 2a reveals that, the hydroxyl group is arranged in a trans configuration

  可以通过相应的乙烯基硝基化合物通过SnCl 2 ·2H 2 O还原而方便地制备一系列新型不饱和肟。肟的结构通过1 H和13 C NMR，IR和HRMS以及X射线晶体学分析进行表征。 1-（6-氯-吡啶-3-基甲基）-4，5-二氢-1H-咪唑-2-甲醛甲醛肟2a表明，羟基以反式构型排列。简短调查的一些证据表明，这些肟似乎是由硝基脂族化合物的aci形式还原而形成的。
• FURAN BASED COMPOSITIONS AND METHODS OF MAKING THEREOF
  申请人：UNIVERSITY OF DELAWARE

  公开号：US20210040055A1

  公开（公告）日：2021-02-11

  Disclosed herein are processes for the preparation of compounds of formula (I) from one or more bio-derived reactants, and their use as base oils: (R 1 -A) b -(CH x ) a (CHR 2 ) m —(C(R 4 R 5 )) n —(CHR 3 ) o —(CH y ) c -(A-R 1′ ) d (I) wherein a and c are independently 0 or 1, b and d are independently 1 or 2, x and y are independently 1 or 2, dependent upon the values of a-d, m and o are independently 0 or 1, n is an integer of 0-6, and each A is independently an unsaturated furan ring, a partially saturated furan ring, a saturated furan ring, or —(CH 2 ) 4 —. Also, R 1 , R 1′ , R 2 , R 3 , R 4 and R 5 are independently selected from the group consisting of H and alkyl groups having 1 to 18 carbon atoms, with a proviso that at least one of R 2 , R 3 , R 4 , and R 5 is not hydrogen, and the total carbon content of the compound of formula (I) is in the range of 20-62.

  本文公开了一种从一个或多个生物衍生反应物制备式（I）化合物的过程，并将其用作基础油：（R1-A）b-（CHx）a（CHR2）m-（C（R4R5））n-（CHR3）o-（CHy）c-（A-R1'）d（I），其中a和c独立地为0或1，b和d独立地为1或2，x和y独立地为1或2，取决于a-d的值，m和o独立地为0或1，n为0-6的整数，每个A独立地为不饱和呋喃环，部分饱和呋喃环，饱和呋喃环或-（CH2）4-。此外，R1、R1'、R2、R3、R4和R5独立地选自H和具有1至18个碳原子的烷基基团的群，但其中至少一个R2、R3、R4和R5不是氢，并且式（I）化合物的总碳含量在20-62的范围内。