2,2'-methylenebis(6-isopropylphenol) | 41514-15-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2'-methylenebis(6-isopropylphenol)
• 英文别名: 2,2'-Dihydroxy-3,3'-diisopropyldiphenylmethan；2,2'-Methylenebis[6-(propan-2-yl)phenol]；2-[(2-hydroxy-3-propan-2-ylphenyl)methyl]-6-propan-2-ylphenol
• CAS: 41514-15-2
• 化学式: C₁₉H₂₄O₂
• 分子量: 284.398
• InChiKey: NFPQMICMHNJBGN-UHFFFAOYSA-N

物化性质

• 熔点：
  75-76 °C(Solv: hexane (110-54-3))
• 沸点：
  407.7±40.0 °C(Predicted)
• 密度：
  1.069±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,2'-methylenebis(6-isopropylphenol) 、 甲基磺酰氯 在 三乙胺 作用下， 以 乙酸乙酯 为溶剂， 反应 0.17h， 以92%的产率得到2,2'-methylenebis[6-(1-methylethyl)]phenol dimesylate
  参考文献：
  名称：

  Chromatography-Free and Eco-Friendly Synthesis of Aryl Tosylates and Mesylates

  摘要：

  Two chromatography-free and eco-friendly protocols have been developed to synthesize aryl tosylates and mesylates by the tosylation and mesylation of the corresponding hydroxyarenes, respectively. These protocols are superior to other known ones regarding the simplicity, reaction time and conditions, the range of substrates, yields, and environmental friendliness.

  DOI：

  10.1055/s-0034-1378867
• 作为产物：
  描述：

  聚合甲醛 、 异丙苯酚 以 xylene 为溶剂， 反应 10.0h， 以82%的产率得到2,2'-methylenebis(6-isopropylphenol)
  参考文献：
  名称：

  Uncatalyzed Phenol-Formaldehyde Reactions. A Convenient Synthesis of Substituted 2,2′-Dihydroxydiphenylmethanes

  摘要：

  DOI：

  10.1055/s-1981-29368

文献信息

• Casiraghi,G. et al., Gazzetta Chimica Italiana, 1978, vol. 108, p. 79 - 84
  作者：Casiraghi,G. et al.

  DOI：——

  日期：——
• Mononuclear tungsten(VI) complexes with methylenebis(6-alkylphenol)s
  作者：Ari Lehtonen、Reijo Sillanpää

  DOI：10.1016/s0277-5387(03)00373-5

  日期：2003.8

  Reaction of monomeric tungsten(VI) complex [W(eg)(3)] (1) (eg = 1,2-ethanediolate dianion) with either one or 2 equiv. of 2,2'-methylenebis(6-alkylphenol) [alkyl = Me (H2L1), Pr-i (H2L2), Bu-t (H2L3)] provides heteroleptic complexes [W(eg)(2)(L-n)] (2) and [W(eg)(L-n)(2)] (3), respectively. Sterically hindered ligand precursor H2L3, which bear bulky tert-butyl groups in ortho-positions, can form only a complex corresponding to formula 2. (C) 2003 Elsevier Ltd. All rights reserved.
• CASIRACHI G.; CASNATI G.; POCHINI A.; PUGLIA G.; UNGARO R.; SARTORI G., SYNTHESIS, 1981, NO 2, 143-146
  作者：CASIRACHI G.、 CASNATI G.、 POCHINI A.、 PUGLIA G.、 UNGARO R.、 SARTORI G.

  DOI：——

  日期：——
• CASIRAGHI G.; CASNATI G.; CORNIA M.; POCHINI A.; PUGLIA G.; SARTORI G.; U+, J. CHEM. SOC. PERKIN TRANS., PART 1, 1978, NO 4, 318-321
  作者：CASIRAGHI G.、 CASNATI G.、 CORNIA M.、 POCHINI A.、 PUGLIA G.、 SARTORI G.、 U+

  DOI：——

  日期：——
• Method for Purifying Polymerizable Fluoromonomer by Distillation
  申请人：Central Glass Company, Limited

  公开号：US20210317065A1

  公开（公告）日：2021-10-14

  The present invention is directed to a purification method for purifying a fluorine-containing polymerizable monomer of the formula (1), in which the fluorine-containing polymerizable monomer is purified by distillation in the coexistence of a phenolic compound A such as 6-tert-butyl-2,4-xylenol and a phenolic compound B such as 2,2′-methylene-bis(4-methyl-6-tert-butylphenol). By the combined use of the phenolic compound A and the phenolic compound B, it is possible to significantly suppress polymerization or oligomerization of the fluorine-containing polymerizable monomer even during industrial-production-scale distillation and efficiently purify the fluorine-containing polymerizable monomer by distillation.