3-(dioctylamino)phenol | 107144-90-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 3-(dioctylamino)phenol
• 英文别名: N,N-di-n-octyl-m-aminophenol
• CAS: 107144-90-1
• 化学式: C₂₂H₃₉NO
• 分子量: 333.558
• InChiKey: DEESEDSYSBALFV-UHFFFAOYSA-N

物化性质

• 沸点：
  460.0±18.0 °C(Predicted)
• 密度：
  0.934±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.5
• 重原子数：
  24
• 可旋转键数：
  15
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3-(dioctylamino)phenol 在 sodium hydroxide 、 copper diacetate 、 溶剂黄146 作用下， 以 乙醇 为溶剂， 生成
  参考文献：
  名称：

  Synthesis of New Dilactone-type Fluorescent Dyes and Their Fluorochromic Properties

  摘要：

  新型二内酯荧光染料已从1,4-萘醌和m-(二烷基氨基)酚合成。染料的荧光峰值和强度因溶剂极性而发生显著变化。这些染料在有序的涤丝液晶中也展现出了良好的荧光二向色性。

  DOI：

  10.1246/cl.1994.2051
• 作为产物：
  描述：

  二正辛胺 在 tris-(dibenzylideneacetone)dipalladium(0) 、 palladium on activated charcoal 、 potassium tert-butylate 、 氢气 、 2-二环己基磷-2',6'-二异丙氧基-1,1'-联苯 作用下， 以 乙酸乙酯 、 甲苯 为溶剂， 反应 18.0h， 生成 3-(dioctylamino)phenol
  参考文献：
  名称：

  Fluorescent Membrane Probes Based on a Coumarin-Thiazole Scaffold

  摘要：

  Biological functions of cell membranes and their correlation to the heterogeneity of the latter's lipid composition are still poorly understood. Fluorescence provides one of the most versatile tools for studying biological membranes. However, few bright and photostable fluorescent probes for labeling plasma membranes are available. We have designed and synthesized two such probes, 8 and 9, that are based on the thiazole-coumarin scaffold. Both are environment sensitive and exhibit similar shifts of emission spectra in a variety of solvents as probes based on 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD). In particular, the second, positively charged probe 9 labels the plasma membrane selectively with limited redistribution to other membranes of the cell. Unfortunately, compared to the other two probes tested, 8 and 6-NBD-PC, it exhibits the highest rate of photobleaching. Nevertheless, these new thiazole-coumarin based membrane probes provide a viable approach to the design of novel membrane probes.

  DOI：

  10.17344/acsi.2019.5089

文献信息

• 一类基于香豆素的近红外的荧光染料及其制备 方法与应用
  申请人：中国科学院理化技术研究所

  公开号：CN103374234B

  公开（公告）日：2016-03-30

  本发明公开了一类基于香豆素的近红外的荧光染料，具有如下结构式I：Y为O、S或者NR11；Z为NR7R8或者OR9；R1、R2、R7、R8、R9、R11分别独立的为氢、烃基、醚基、取代烷基、酰基或芳基；R3、R5、R6、R10、R12、R13分别独立的为氢、低级烃基或卤素；R4为氢、低级烃基、取代烷基或卤素；为阴离子；还公开了该类染料的制备方法。这类染料具有良好的生物相容性、低毒性、较长的荧光发射和较高的荧光量子产率，可以避免背景荧光，用于生物体系中生物大分子如核酸或蛋白质等的共价荧光标记；对于研究疾病或者生物的发育、繁殖、遗传和变异有非常重要的作用。
• Labeling of Microthrix parvicella in situ: A novel FRET probe based on bisoctyl rhodamine B
  作者：Yingchun Gu、Dayong Lin、Xuening Fei、Yongqiang Chen、Cuihong Wang、Qi Yang、Yalin Tang

  DOI：10.1016/j.saa.2019.01.057

  日期：2019.4

  mainly responsible for bulking or foaming of activated sludge. Based on the affinity of M. parvicella to the hydrophobic characteristics of long-chain fatty acids, a novel bisoctyl rhodamine B (BORB) and a novel fluorescence resonance energy transfer (FRET) complex probe were prepared herein to study their properties. When the FRET probe was used in in situ activated sludge, M. parvicella was clearly labeled

  丝状细菌，特别是Microthrix parvicella，主要是导致活性污泥膨胀或起泡的原因。基于的亲和力M. parvicella到的长链脂肪酸，一种新颖的bisoctyl若丹明B（BORB）和一种新颖的荧光共振能量转移（FRET）探针复合物，制备本文中以研究它们的性质的疏水特性。当使用原位活化污泥FRET探针，M. parvicella被清楚地标示为20 nmol / L的，这是相比于BORB（1微摩尔/ L）单独和500倍的相比，减少了50倍咔唑喹啉探针已有报道。用荧光原位杂交，比较M. parvicella可以使用BORB和FRET探针原位清楚地标记，而无需进行复杂的预处理（例如，电击和破碎过程，固定的样品，消化和溶菌酶处理）。这项研究讨论了在预警扩展中为标记小枝粘杆菌而开发的简便方法，从而抑制和控制了原位污泥的堆积。
• Quantitative investigations of the aggregation behaviour of hydrophobic anilino squaraine dyes through UV/vis spectroscopy and dynamic light scattering
  作者：James Wojtyk、Andrew McKerrow、Peter Kazmaier、Erwin Buncel

  DOI：10.1139/v99-073

  日期：1999.6.1

  In continuing studies of the aggregation behaviour of squaraine dyes in DMSO-water mixtures, we have examined a series of symmetrical anilino-based squaraines with increasing N-alkyl chain length (n-butyl, n-octyl, and n-dodecyl). The aggregation behaviour was assessed through UV/vis spectroscopic and Dynamic Light Scattering (DLS) studies with quantitative interpretation based on exciton theory. This class of N-alkyl squaraines forms two distinct solution aggregates, Type J and Type H, depending on the composition of the DMSO-water medium. DLS measurement of the aggregates in the Type J and Type H morphologies showed that (i) the particle diameter increased with increasing hydrophobicity; (ii) DMSO has a large effect on the aggregate size; (iii) Type J aggregates are of equal dimensions with Type H aggregates. Moreover, even though as the DMSO-water solvent composition is varied the UV/vis spectra of Type H and Type J aggregates remained unchanged, the number of molecules comprising each aggregate varies widely. It is proposed that the dynamic conversion (J →> H) results from intramolecular reorganization of individual molecules within the aggregate. Quantification of aggregation through DLS has further developed the "kinetic" versus "thermodynamic" control model of dye aggregation.Key words: squaraine, dynamic light scattering, DMSO-water mixtures, self-assembly, kinetic/thermodynamic control.

  在研究Squaraine染料在DMSO-水混合物中的聚集行为的持续研究中，我们研究了一系列对称的基于苯胺的Squaraine，其N-烷基链长度逐渐增加（正丁基，正辛基和正十二烷基）。通过UV / vis光谱和动态光散射（DLS）研究对聚集行为进行了评估，并基于激子理论进行了定量解释。这类N-烷基Squaraine形成两种不同的溶液聚集体，J型和H型，取决于DMSO-水介质的组成。在J型和H型形态的聚集体的DLS测量中，显示出（i）颗粒直径随着疏水性的增加而增加；（ii）DMSO对聚集体大小有很大影响；（iii）J型聚集体与H型聚集体的尺寸相等。此外，即使在DMSO-水溶剂组成变化时，H型和J型聚集体的UV / vis光谱保持不变，每个聚集体包含的分子数仍然变化很大。提出了动态转化（J → H）是由聚集体内单个分子的分子内重排导致的。通过DLS对聚集进行量化，进一步发展了染料聚集的“动力学”与“热力学”控制模型。 关键词：Squaraine，动态光散射，DMSO-水混合物，自组装，动力学/热力学控制。
• Anthraquinone compound and water-based ink-jet recording ink containing the compound
  申请人：——

  公开号：US20030078318A1

  公开（公告）日：2003-04-24

  It is disclosed that in ink for ink jet recording, containing at least a water-insoluble coloring matter, water and a resin as main components to form an emulsion, anthraquinone compounds represented by at least the following the formula (1) 1 especially those in which X is an oxygen atom, R 1 is represented by the formula (2) 2 and further R 8 is —NR 12 R 13 , are useful as coloring matters excellent in water resistance and also in light fastness and compatibility with a resin and that ink for ink jet recording using the same and exhibiting excellent performances in light fastness and storage stability, especially as ink of an ink jet recording system, can forma high-quality, unblotted image, a recorded image having also excellent property in water resistance.

  本发明涉及一种墨水喷射记录用墨水，其包含至少一种水不溶性着色剂、水和树脂作为主要组成部分形成乳液，其中所述着色剂为至少以下式（1）所表示的蒽醌化合物1，特别是其中X为氧原子，R1为式（2）所表示的基团2，进一步地，R8为—NR12R13，这些着色剂不仅具有优异的耐水性、耐光性和与树脂的相容性，而且使用该墨水喷射记录的墨水表现出优异的耐光性和储存稳定性，特别是作为喷墨记录系统的墨水，能够形成高质量、无污点的图像，记录的图像也具有优异的耐水性。
• Fluorescent dyes
  申请人：SYNTEX (U.S.A.) INC.

  公开号：EP0356173A2

  公开（公告）日：1990-02-28

  The present invention describes a class of dyes for use in staining cell samples and methods of making such dyes. A preferred class of dyes known as detergent dyes which possess the ability to stain cells in whole blood and are only slowly leached or lost from the stained cells over time are described. The present invention has application, for example, to blood typing for the determination of the presence of blood group antigens A, B, AB, O, and D (Rho) and antibodies to such antigens.

  本发明描述了一类用于细胞样本染色的染料和制造这类染料的方法。本发明描述了一类被称为去污剂染料的优选染料，这类染料能够对全血中的细胞进行染色，而且随着时间的推移，只会从被染色的细胞中缓慢地渗出或流失。例如，本发明可应用于血型鉴定，以确定是否存在血型抗原 A、B、AB、O 和 D（Rho）以及此类抗原的抗体。