piperazine-1,4-dicarbothioic acid dianilide | 6337-94-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: piperazine-1,4-dicarbothioic acid dianilide
• 英文别名: piperazine-1,4-bis-carbothioic acid-dianilide；Piperazin-1,4-bis-thiocarbonsaeure-dianilid；N,N'-diphenylpiperazine-1,4-dicarbothioamide；1-N,4-N-diphenylpiperazine-1,4-dicarbothioamide
• CAS: 6337-94-6
• 化学式: C₁₈H₂₀N₄S₂
• mdl: MFCD00170216
• 分子量: 356.516
• InChiKey: OZJSIZWZVYVUQC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  24
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  94.7
• 氢给体数：
  2
• 氢受体数：
  2

安全信息

• 海关编码：
  2933599090

反应信息

• 作为产物：
  描述：

  哌嗪 、 硫代异氰酸苯酯 以 苯 为溶剂， 反应 1.0h， 以97%的产率得到piperazine-1,4-dicarbothioic acid dianilide
  参考文献：
  名称：

  Drugarin; Drugarin, Pharmazie, 1981, vol. 36, # 9, p. 647 - 648

  摘要：

  DOI：

文献信息

• van Alphen, Recueil des Travaux Chimiques des Pays-Bas, 1938, vol. 57, p. 265,276
  作者：van Alphen

  DOI：——

  日期：——
• Anti-Arenaviral Compounds
  申请人：Amberg Sean M.

  公开号：US20120308519A1

  公开（公告）日：2012-12-06

  Described herein are 4-methyl-piperazine-1-carbothioic acid amide derivatives and analogs, as well as compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by hemorrhagic fever viruses, such as Arenaviruses.
• ANTI-ARENAVIRAL COMPOUNDS
  申请人：SIGA TECHNOLOGIES, INC.,

  公开号：US20140301979A1

  公开（公告）日：2014-10-09

  Described herein are 4-methyl-piperazine-1-carbothioic acid amide derivatives and analogs, as well as compositions containing the same, for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by hemorrhagic fever viruses, such as Arenaviruses.
• US8791110B2
  申请人：——

  公开号：US8791110B2

  公开（公告）日：2014-07-29
• Drugarin; Drugarin, Pharmazie, 1981, vol. 36, # 9, p. 647 - 648
  作者：Drugarin、Drugarin

  DOI：——

  日期：——