环戊二烯并[b]吲哚-7-甲醛,1,2,3,3a,4,8b-六氢-4-苯基- | 145304-23-0

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 环戊二烯并[b]吲哚-7-甲醛,1,2,3,3a,4,8b-六氢-4-苯基-
• 英文名称: 4-phenyl-1,2,3,3a,4,8b-hexahydrocyclopenta[b]indole-7-carbaldehyde
• 英文别名: 4-phenyl-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]indole-7-carbaldehyde
• CAS: 145304-23-0
• 化学式: C₁₈H₁₇NO
• 分子量: 263.339
• InChiKey: IEVQFMVXOZCRQS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.28
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  环戊二烯并[b]吲哚-7-甲醛,1,2,3,3a,4,8b-六氢-4-苯基- 、 3-羧甲基绕丹宁 在 ammonium acetate 、 溶剂黄146 作用下， 反应 0.5h， 以66%的产率得到2-[(5Z)-4-oxo-5-[(4-phenyl-2,3,3a,8b-tetrahydro-1H-cyclopenta[b]indol-7-yl)methylidene]-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid
  参考文献：
  名称：

  ORGANIC DYE, PHOTOELECTRIC TRANSDUCING MATERIAL, SEMICONDUCTOR ELECTRODE, AND PHOTOELECTRIC TRANSDUCING DEVICE

  摘要：

  公开号：

  EP1526159B1
• 作为产物：
  描述：

  4-phenyl-1,2,3,3a,4,8b-hexahydrocyclopenta[b]indole 、 N,N-二甲基甲酰胺 在 三氯氧磷 作用下， 以70%的产率得到环戊二烯并[b]吲哚-7-甲醛,1,2,3,3a,4,8b-六氢-4-苯基-
  参考文献：
  名称：

  Substituent effects in a double rhodanine indoline dye on performance of zinc oxide dye-sensitized solar cell

  摘要：

  The solar-light-to-electricity conversion efficiency of substituted indoline dyes depended on short-circuit photocurrent density which is affected by maximum incident photon-to-current efficiency. The oxidation potential of the double rhodanine indoline dyes needed to be >similar to 0.2 V vs Fc/Fc(+) in acetonitrile to show high incident photon-to-current efficiency in a zinc oxide, dye-sensitized solar cell. To make a molecular design of highly efficient indoline dyes, the HOMO energy level should be more negative than similar to-4.9 eV by the DFT calculations. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2009.12.009

文献信息

• [EN] CANCER CELL INHIBITORY DRUG AND CANCER STEM-CELL DETECTION PROBE<br/>[FR] MÉDICAMENT INHIBITEUR DE CELLULES CANCÉREUSES ET SONDE DE DÉTECTION DE CELLULES SOUCHES CANCÉREUSES
  申请人：CANON KK

  公开号：WO2014065440A1

  公开（公告）日：2014-05-01

  An object of the present invention is to provide a cancer cell inhibitory drug, particularly a cancer stem-cell inhibitory drug, or a cancer stem-cell detection probe.A cancer cell inhibitory drug containing at least a compound represented by general formula (1).

  本发明的目的是提供一种抗癌药物，特别是一种抗癌干细胞的药物，或一种癌干细胞检测探针。一种抗癌细胞的药物，其中至少包含一个由通式（1）表示的化合物。
• Evaluation probe for central nervous system permeability, evaluation method for central nervous system permeability, and screening method using an evaluation probe for central nervous system permeability
  申请人：Tanaka Toshio

  公开号：US10227337B2

  公开（公告）日：2019-03-12

  Provided is an evaluation probe capable of optically evaluating permeability of a substance through a central nervous system tissue. Also provided is an evaluation method for permeability of a substance through a central nervous system tissue using an evaluation probe for central nervous system permeability. Also provided is a screening method using an evaluation probe for central nervous system permeability. The evaluation probe for central nervous system permeability includes, as an active ingredient, at least one kind of compound represented by the following general formula (1).

  提供的是一种评估探针，能够光学评估物质通过中枢神经系统组织的渗透性。同时提供了一种使用中枢神经系统渗透性评估探针评估物质渗透性的评估方法。还提供了一种使用中枢神经系统渗透性评估探针进行筛选的方法。中枢神经系统渗透性评估探针包括至少一种由下列通式（1）表示的化合物作为活性成分。
• Organic dye, photoelectric transducing material, semiconductor electrode, and photoelectric transducing device
  申请人：Mitsubishi Paper Mills Limited

  公开号：EP1997855A2

  公开（公告）日：2008-12-03

  Disclosed are an organic dye having a specific structure, a photoelectric conversion material containing the dye, a semiconductor electrode formed of a substrate having an electrically conductive surface, a semiconductor layer coated on the electrically conductive surface and the above dye adsorbed on the surface, and a photoelectric conversion device to which the above dye is applied. The present invention uses the above dye and can therefore provide a photoelectric conversion device excellent in photoelectric conversion efficiency, and the photoelectric conversion device is suitable for use in a solar cell or the like.

  本发明公开了一种具有特定结构的有机染料，一种含有该染料的光电转换材料，一种由具有导电表面的基板、涂覆在导电表面上的半导体层和吸附在该表面上的上述染料构成的半导体电极，以及一种应用了上述染料的光电转换装置。 本发明使用了上述染料，因此可以提供一种光电转换效率极佳的光电转换装置，该光电转换装置适用于太阳能电池等。
• Method of inhibiting cancer cell, method for detecting cancer cell, and system for detecting cancer cell
  申请人：CANON KABUSHIKI KAISHA

  公开号：US10220024B2

  公开（公告）日：2019-03-05

  An object of the present invention is to provide a cancer cell inhibitory drug, particularly a cancer stem-cell inhibitory drug, or a cancer stem-cell detection probe. A cancer cell inhibitory drug containing at least a compound represented by general formula (1).

  本发明的目的是提供一种癌细胞抑制药物，特别是癌干细胞抑制药物或癌干细胞检测探针。一种癌细胞抑制药物至少含有通式（1）代表的化合物。
• Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device
  申请人：Horiuchi Tamotsu

  公开号：US20080149175A1

  公开（公告）日：2008-06-26

  Disclosed are an organic dye having a specific structure, a photoelectric conversion material containing the dye, a semiconductor electrode formed of a substrate having an electrically conductive surface, a semiconductor layer coated on the electrically conductive surface and the above dye adsorbed on the surface, and a photoelectric conversion device to which the above dye is applied. The present invention uses the above dye and can therefore provide a photoelectric conversion device excellent in photoelectric conversion efficiency, and the photoelectric conversion device is suitable for use in a solar cell or the like.