phenyl o-toluenesulfonate | 91903-33-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: phenyl o-toluenesulfonate
• 英文别名: toluene-2-sulfonic acid phenyl ester；Toluol-2-sulfonsaeure-phenylester；Phenol toluenesulfonate；phenyl 2-methylbenzenesulfonate
• CAS: 91903-33-2
• 化学式: C₁₃H₁₂O₃S
• 分子量: 248.302
• InChiKey: ODOPFDLFKUKZCU-UHFFFAOYSA-N

物化性质

• 沸点：
  391.8±25.0 °C(Predicted)
• 密度：
  1.245±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  51.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  phenyl o-toluenesulfonate 在 lithium diisopropyl amide 作用下， 以 四氢呋喃 为溶剂， 反应 4.67h， 生成 2-[2-(2-Sulfino-phenyl)-ethyl]-benzenesulfonic acid phenyl ester
  参考文献：
  名称：

  Base induced coupling-condensations of phenyl p-toluenesulfonate and of N-methyl-p-toluenesulfonanilide

  摘要：

  DOI：

  10.1021/jo00350a095
• 作为产物：
  描述：

  sodium phenoxide 、 邻甲苯磺酰氯 在 水 作用下， 生成 phenyl o-toluenesulfonate
  参考文献：
  名称：

  DE91314

  摘要：

  公开号：

文献信息

• PROCESS FOR PRODUCING AROMATIC AMINES
  申请人：TAKASAGO INTERNATIONAL CORPORATION

  公开号：US20020035295A1

  公开（公告）日：2002-03-21

  The present invention provides an activator in arylamination using a palladium compound as a catalyst, which is superior to conventional phosphines in stability and performance. With the phosphine sulfide as an activator, an arylamination reaction achieves improved selectivity to produce a desired aromatic amine in an obviously increased yield as compared with a reaction using the corresponding phosphine compound. Moreover, the phosphine sulfide of the invention is impervious to oxidation and exists stably in air and therefore sufficiently withstands use on an industrial scale.

  本发明提供了一种在芳基化反应中使用钯化合物作为催化剂的活化剂，其在稳定性和性能方面优于传统的膦化合物。通过使用膦硫化物作为活化剂，芳基化反应实现了改善的选择性，以明显增加的产量生产所需的芳香胺，与使用相应的膦化合物的反应相比。此外，本发明的膦硫化物不受氧化影响，在空气中存在稳定，因此足以在工业规模上使用。
• 2,2 (Diarlyl) Vinylphosphine compound, palladium catalyst thereof, and process for producing arylamine, diaryl, or arylalkyne with the catalyst
  申请人：——

  公开号：US20020058837A1

  公开（公告）日：2002-05-16

  A novel 2,2-(diaryl)vinylphosphine compound represented by the following general formula (1): 1 (wherein R 1 is a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, an alicyclic group having 5 to 7 carbon atoms, etc.; R 2 , R 3 , R 4 , R 5 , R 6 , and R 7 may be the same or different and each is an alkyl group having 1 to 6 carbon atoms, an alicyclic group having 5 to 7 carbon atoms, etc., provided that R 4 and R 5 taken together and/or R 6 and R 7 taken together may represent a fused benzene ring, a substituted fused benzene ring, a trimethylene group, etc.; and p, q, r, and s each is 0 to 5, provided that p+q and r+s each is in the range of from 0 to 5); a palladium-phosphine catalyst obtained by causing a palladium compound to act on the novel 2,2-(diaryl)vinylphosphine compound; and a process for obtaining an arylamine, a diaryl and an arylalkyne in the presence of the palladium-phosphine catalyst.

  一种由以下通用公式（1）表示的新型2,2-(二芳基)乙烯膦化合物：其中R1是氢原子、具有1至6个碳原子的烷基基团、具有5至7个碳原子的脂环基团等；R2、R3、R4、R5、R6和R7可能相同或不同，每个是具有1至6个碳原子的烷基基团、具有5至7个碳原子的脂环基团等，但要求R4和R5一起和/或R6和R7一起可能代表融合苯环、取代融合苯环、三亚甲基基团等；p、q、r和s每个为0至5，但要求p+q和r+s分别在0至5的范围内；通过使钯化合物作用于新型2,2-(二芳基)乙烯膦化合物而获得的钯-膦催化剂；以及在钯-膦催化剂存在下获得芳胺、二芳基和芳基炔的方法。
• SuFEx Reactions of Sulfonyl Fluorides, Fluorosulfates, and Sulfamoyl Fluorides Catalyzed by N-Heterocyclic Carbenes
  作者：Muze Lin、Jinyun Luo、Yu Xie、Guangfen Du、Zhihua Cai、Bin Dai、Lin He

  DOI：10.1021/acscatal.3c03820

  日期：2023.11.17

  Sulfur(VI) fluoride exchange (SuFEx) click chemistry provides a powerful tool for the rapid assembly of modular connections. Herein, we report an organocatalytic SuFEx reaction of sulfonyl fluorides, fluorosulfates, and sulfamoyl fluorides. Under the catalysis of 10 mol % N-heterocyclic carbene (NHC), or under the relay catalysis of NHC and HOBt, different SuFExable hubs efficiently undergo click reactions

  硫 (VI) 氟化物交换 (SuFEx) 点击化学为快速组装模块化连接提供了强大的工具。在此，我们报道了磺酰氟、氟硫酸盐和氨磺酰氟的有机催化 SuFEx 反应。在10 mol% N-杂环卡宾（NHC）的催化下，或在NHC和HOBt的中继催化下，不同的SuFExable中心可以有效地与醇或胺发生点击反应，生成磺酸盐、磺酰胺、硫酸盐、氨基磺酸盐和磺酰胺49 –99% 的收益率。通过该方法已制备了190多种磺酰化产物，其中包括25种天然产物衍生物。机理研究表明，NHCs 可能充当以碳为中心的布朗斯台德碱，通过形成氢键来活化醇或胺。
• Polycarbonate resin composition
  申请人：MITSUBISHI ENGINEERING-PLASTICS CORPORATION

  公开号：EP0753540A2

  公开（公告）日：1997-01-15

  A polycarbonate resin composition according to the present invention is suited to be used for medical supplies or appliances and shows a very low yellow discoloration when exposed to an ionizing radiation for sterilization. The polycarbonate resin composition comprises 100 parts by weight of a polycarbonate resin; 0.01 to 5 parts by weight of an aromatic compound containing oxy group or carbonyl group; and 0.01 to 5 parts by weight of at least one compound selected from the group consisting of: (A) a compound containing cyclic acetal group; (B) a sulfone compound; (C) a sulfoxide compound; (D) polyalkylene glycol, an ether of polyalkylene glycol or an ester of polyalkylene glycol; (E) a compound containing sulfonate group; and (F) an aromatic hydrocarbon-aldehyde resin.

  根据本发明的一种聚碳酸酯树脂组合物适合用于医疗用品或器具，在暴露于电离辐射灭菌时，黄色褪色程度很低。聚碳酸酯树脂组合物包括 100 重量份的聚碳酸酯树脂；0.01 至 5 重量份的含氧基或羰基的芳香族化合物；以及 0.(A) 含环缩醛基团的化合物；(B) 砜化合物；(C) 亚砜化合物；(D) 聚亚烷基二醇、聚亚烷基二醇的醚或聚亚烷基二醇的酯；(E) 含磺酸基团的化合物；(F) 芳香烃-醛树脂。
• Polycarbonate resin composition stabilized against radiation
  申请人：MITSUBISHI ENGINEERING-PLASTICS CORPORATION

  公开号：EP0794218A2

  公开（公告）日：1997-09-10

  The present invention relates to a polycarbonate resin composition comprising 100 parts by weight of a polycarbonate resin; 0.01 to 5 parts by weight of a compound containing oxymethylene unit, a compound containing oxymethylene unit having substituent or a cyclic ether compound having substituent.

  本发明涉及一种聚碳酸酯树脂组合物，该组合物包括 100 重量份的聚碳酸酯树脂； 0.01 至 5 重量份的含氧亚甲基单元的化合物、含氧亚甲基单元且具有取代基的化合物或 具有取代基的环醚化合物。