ethoxycarbonyl-formamidoxime | 114252-64-1

• 分子结构分类: 有机化合物 - 有机1,3-偶极化合物 - 炔丙基型1，3-偶极有机化合物
• 英文名称: ethoxycarbonyl-formamidoxime
• 英文别名: ethyl N-[(E)-hydroxyiminomethyl]carbamate
• CAS: 114252-64-1
• 化学式: C₄H₈N₂O₃
• mdl: MFCD19227046
• 分子量: 132.119
• InChiKey: RWWBQEQQATYWJI-UHFFFAOYSA-N

物化性质

• 密度：
  1.24±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  70.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  ethoxycarbonyl-formamidoxime 、 对氯甲苯 在 吡啶 作用下， 以 5,5-dimethyl-1,3-cyclohexadiene 、 氯仿 为溶剂， 生成 5-p-tolyl-[1,2,4]oxadiazole-3-carboxylic acid ethyl ester
  参考文献：
  名称：

  Mono- or disubstituted 1,2,4,oxadiazoles which are substituted by at

  摘要：

  1,2,4-氧代唑具有3-和5-位取代基，可以是氢原子，脂肪族，环脂族，芳基脂族，芳基或杂环基团，或者是具有-- CONR.sup.1 R.sup.2 公式的氨基甲酰基团，其中 R.sup.1 和 R.sup.2 可以相同也可以不同，可以是氢原子或脂肪族，环脂族，芳基脂族或芳基基团，或者与N原子结合形成杂环结构；前提是3-或5-位的至少一个取代基是N-取代的氨基甲酰基团。这一类化合物表现出抗微生物活性，尤其是抗病毒、抗寄生虫和抗菌活性。相应的氧代唑环也有描述，并且在氧代唑的制备中是有用的中间体。

  公开号：

  US03991067A1

文献信息

• 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides
  申请人：——

  公开号：US20030162812A1

  公开（公告）日：2003-08-28

  The present invention relates to 4-Haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, Processes for Their Preparation, Compositions Comprising Them, and Their Use as Pesticides More particularly, the present invention relates to 4-trifluoromethyl-3-oxadiazolylpyridines of the formula (I′), to processes for their preparation, to compositions comprising them and to the use of these compounds for controlling animal pests, in particular insects, spider mites, ectoparasites and helminths: 1 wherein X, Y are as defined in the description.

  本发明涉及4-卤代烷基-3-杂环基吡啶、4-卤代烷基-5-杂环基嘧啶和4-三氟甲基-3-噁唑基吡啶的制备方法，包含它们的组合物以及它们作为杀虫剂的用途。特别地，本发明涉及式(I')的4-三氟甲基-3-噁唑基吡啶，它们的制备方法，包含它们的组合物以及这些化合物用于控制动物害虫，特别是昆虫、蜘蛛螨、外寄生虫和蠕虫的用途：1其中X、Y在说明中定义。
• 4-haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclylpyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides
  申请人：Hoechst Schering AgrEvo GmbH

  公开号：US06239160B1

  公开（公告）日：2001-05-29

  The present invention relates to 4-haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclylpyrimidines of the formula (I), to processes for their preparation, to compositions comprising them, and to the use of these compounds for controlling animal pests, in particular insects, spider mites, ectoparasites and helminths. In the formula (I), Q is a 5-membered heterocyclic group which is optionally substituted by halogen or organic radicals, Y is halo-C1-C8-alkyl, X is CH or N and m is 0 or 1.

  本发明涉及式(I)的4-卤代烷基-3-杂环基吡啶和4-卤代烷基-5-杂环基嘧啶，以及它们的制备方法、包含它们的组合物，以及这些化合物用于控制动物害虫，特别是昆虫、蜘蛛螨、寄生虫和蠕虫的用途。在式(I)中，Q是一个5-成员杂环基，可以被卤素或有机基团取代，Y是卤代C1-C8-烷基，X是CH或N，m为0或1。
• 4-HALOALKYL-3-HETEROCYCLYLPYRIDINES, 4-HALOALKYL-5-HETEROCYCLYL-PYRIMIDINES AND 4-TRIFLUOROMETHYL-3-OXADIAZOLYLPYRIDINES, PROCESSES FOR THEIR PREPARATION, COMPOSITIONS COMPRISING THEM, AND THEIR USE AS PESTICIDES
  申请人：Hoechst Schering AgrEvo GmbH

  公开号：US06699853B2

  公开（公告）日：2004-03-02

  The present invention relates to 4-Haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, Processes for Their Preparation, Compositions Comprising Them, and Their Use as Pesticides More particularly, the present invention relates to 4-trifluoromethyl-3-oxadiazolylpyridines of the formula (I′), to processes for their preparation, to compositions comprising them and to the use of these compounds for controlling animal pests, in particular insects, spider mites, ectoparasites and helminths: wherein X, Y are as defined in the description.

  本发明涉及4-卤代烷基-3-杂环基吡啶、4-卤代烷基-5-杂环基嘧啶和4-三氟甲基-3-噁唑基吡啶，以及它们的制备方法、包含它们的组合物和它们作为杀虫剂的用途。更具体地，本发明涉及式(I')的4-三氟甲基-3-噁唑基吡啶，以及其制备方法、包含它们的组合物和这些化合物用于控制动物害虫，特别是昆虫、蜘蛛螨、寄生虫和蠕虫的用途。其中X，Y在说明中定义。
• Mono- or disubstituted 1,2,4,oxadiazoles which are substituted by at
  申请人：Glaxo Laboratories Limited

  公开号：US03991067A1

  公开（公告）日：1976-11-09

  1,2,4-Oxadiazoles having as 3- and 5-substituents a hydrogen atom, an aliphatic, cycloaliphatic, araliphatic, aryl or heterocyclic group, or a carbamoyl group of the formula -- CONR.sup.1 R.sup.2 where R.sup.1 & R.sup.2 which can be the same or different, are hydrogen atoms or aliphatic, cycloaliphatic, araliphatic or aryl groups or, taken with the N atom, a heterocvolic ring; provided that at least one of the 3- or 5-substituents is an N-substituted carbamoyl group. Antimicrobial activity, and particularly antiviral, antiparasitic and antibacterial activity is shown in this group. The corresponding oxadiazolins are also described and are useful intermediates in the preparation of the oxadiazoles.

  1,2,4-氧代唑具有3-和5-位取代基，可以是氢原子，脂肪族，环脂族，芳基脂族，芳基或杂环基团，或者是具有-- CONR.sup.1 R.sup.2 公式的氨基甲酰基团，其中 R.sup.1 和 R.sup.2 可以相同也可以不同，可以是氢原子或脂肪族，环脂族，芳基脂族或芳基基团，或者与N原子结合形成杂环结构；前提是3-或5-位的至少一个取代基是N-取代的氨基甲酰基团。这一类化合物表现出抗微生物活性，尤其是抗病毒、抗寄生虫和抗菌活性。相应的氧代唑环也有描述，并且在氧代唑的制备中是有用的中间体。