thiophene-2-(N,N-bis(diphenylphosphino)methylamine) | 1215198-72-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: thiophene-2-(N,N-bis(diphenylphosphino)methylamine)
• 英文别名: N,N-bis(diphenylphosphino)thiophen-2-ylmethylamine；N-thiophene-2-methyl-bis(diphenylphosphanyl)amine；(Ph2P)2NCH2-C4H3S；N,N-bis(diphenylphosphanyl)-1-thiophen-2-ylmethanamine
• CAS: 1215198-72-3
• 化学式: C₂₉H₂₅NP₂S
• 分子量: 481.538
• InChiKey: YIPAYYODWJRXQO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.5
• 重原子数：
  33
• 可旋转键数：
  8
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.03
• 拓扑面积：
  31.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  thiophene-2-(N,N-bis(diphenylphosphino)methylamine) 在 双氧水 作用下， 以 四氢呋喃 、 水 为溶剂， 生成 (Ph2P(O))2NCH2-C4H3S
  参考文献：
  名称：

  氨基膦配体的钌配合物及其在芳族酮转移加氢中作为前催化剂的用途：噻吩-2-（N-二苯基硫代膦基）甲胺的X射线晶体结构

  摘要：

  与PPH的一个或二当量噻吩-2-甲胺的反应2中的净的存在氯3，前进的THF，得到噻吩-2-（Ñ -diphenylphosphino）甲胺，1A和噻吩-2-（Ñ，ñ -双（二苯基膦基）甲胺，分别在厌氧条件下2a。用过氧化氢水溶液，元素硫或灰色硒氧化1a和2a，得到相应的氧化物，硫化物和硒化物[Ph 2 P（E）NHCH 2 -C 4 H 3 S]（E：O 1b，S 1c，Se 1d）和[（Ph 2 P（E））2 NCH 2 -C 4 H 3 S]，（E：O 2b，S 2c，Se 2d），高收率。此外，两个新颖的Ru（II）与所述P-N配体的络合物1A和2A，合成开始于复杂的[Ru（η 6 - p -cymene）（μ-Cl）的CL] 2。通过分析和光谱方法对配合物进行了充分表征。31 P– { 1 H} NMR，DEPT，1 H– 13 C HETCOR或1 H–1 H COZY相关性实验

  DOI：

  10.1016/j.poly.2010.12.011
• 作为产物：
  描述：

  2-噻吩甲胺 、 二苯基氯化膦 在 三乙胺 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以94%的产率得到thiophene-2-(N,N-bis(diphenylphosphino)methylamine)
  参考文献：
  名称：

  氨基膦配体的钌配合物及其在芳族酮转移加氢中作为前催化剂的用途：噻吩-2-（N-二苯基硫代膦基）甲胺的X射线晶体结构

  摘要：

  与PPH的一个或二当量噻吩-2-甲胺的反应2中的净的存在氯3，前进的THF，得到噻吩-2-（Ñ -diphenylphosphino）甲胺，1A和噻吩-2-（Ñ，ñ -双（二苯基膦基）甲胺，分别在厌氧条件下2a。用过氧化氢水溶液，元素硫或灰色硒氧化1a和2a，得到相应的氧化物，硫化物和硒化物[Ph 2 P（E）NHCH 2 -C 4 H 3 S]（E：O 1b，S 1c，Se 1d）和[（Ph 2 P（E））2 NCH 2 -C 4 H 3 S]，（E：O 2b，S 2c，Se 2d），高收率。此外，两个新颖的Ru（II）与所述P-N配体的络合物1A和2A，合成开始于复杂的[Ru（η 6 - p -cymene）（μ-Cl）的CL] 2。通过分析和光谱方法对配合物进行了充分表征。31 P– { 1 H} NMR，DEPT，1 H– 13 C HETCOR或1 H–1 H COZY相关性实验

  DOI：

  10.1016/j.poly.2010.12.011

文献信息

• Novel half-sandwich η⁵ -Cp *-rhodium(III) and η⁵ -Cp *-ruthenium(II) complexes bearing bis(phosphino)amine ligands and their use in the transfer hydrogenation of aromatic ketones
  作者：Fatih Ok、Murat Aydemir、Feyyaz Durap、Akın Baysal

  DOI：10.1002/aoc.3068

  日期：2014.1

  Two new half‐sandwich η5‐Cp*–rhodium(III) and η5‐Cp*–ruthenium(II) complexes have been prepared from corresponding bis(phosphino)amine ligands, thiophene‐2‐(N,N‐bis(diphenylphosphino)methylamine) or furfuryl‐2‐(N,N‐bis(diphenylphosphino)amine). Structures of the new complexes have been elucidated by multinuclear one‐ and two‐dimensional NMR spectroscopy, elemental analysis and IR spectroscopy. These

  两个新的半夹心η 5 -Cp * -铑（III）和η 5 -Cp * -钌（II）络合物已经从相应的双（膦）胺配体来制备，噻吩-2-（Ñ，Ñ双（二苯基膦基甲胺）或糠基-2-（N，N-双（二苯基膦基）胺）。通过多核一维和二维NMR光谱，元素分析和IR光谱阐明了新络合物的结构。这些带有双（膦）胺配体的Cp *-铑（III）和Cp *-钌（II）配合物已成功地用于转移2-丙醇对各种酮的氢化作用。版权所有©2013 John Wiley＆Sons，Ltd.
• Rhodium-catalyzed transfer hydrogenation with functionalized bis(phosphino)amine ligands
  作者：Murat Aydemir、Nermin Meric、Cezmi Kayan、Fatih Ok、Akın Baysal

  DOI：10.1016/j.ica.2012.12.005

  日期：2013.3

  complex [Rh(cod)2]BF4. The structural elucidation of the complexes was carried out by elemental analyses, IR and multinuclear NMR spectroscopic data. Furthermore, the complexes were applied to the transfer hydrogenation of ketones in the presence of 2-propanol as the hydrogen source. Catalytic studies showed that all complexes are excellent catalytic precursors for the transfer hydrogenation of aryl alkyl

  从配合物[Rh（cod）2 ] BF 4开始，已经制备了一系列具有P–N–P配体的新型阳离子单核铑（I）配合物。通过元素分析，IR和多核NMR光谱数据对复合物进行结构解析。此外，在2-丙醇作为氢源的存在下，将络合物用于酮的氢化转移。催化研究表明，所有配合物都是在0.1 M iso -PrOH溶液中芳基烷基酮转移加氢的出色催化前体。特别是，[Rh（（Ph 2 P）2 N-C 6 H 4 -4-CH（CH 3）2）（cod）] BF 4充当出色的催化剂，以高达99％的出色转化率提供相应的醇（TOF⩽1980 h -1）。
• Syntheses, Structures, and Catalytic Ethylene Oligomerization Behaviors of Bis(phosphanyl)aminenickel(II) Complexes Containing <i>N</i> ‐Functionalized Pendant Groups
  作者：Keming Song、Haiyang Gao、Fengshou Liu、Jin Pan、Lihua Guo、Shaobo Zai、Qing Wu

  DOI：10.1002/ejic.200900256

  日期：2009.7

  N-functionalized bis(phosphanyl)amine ligands respectively containing benzyl, furfuryl, thiophene-2-methyl, thiophene-2-ethyl, and 2-picolyl groups (1a–e) were synthesized and characterized. The ligands reacted with (DME)NiBr2 in CH2Cl2 to give their corresponding nickel complexes [Ph2PN(R)PPh2NiBr2] [R = CH2C6H5 (2a), CH2C4H3O (2b), CH2C4H3S (2c), CH2C5H4N (2d), and CH2CH2C4H3S (2e)]. The structures of these

  合成并表征了分别含有苄基、糠基、噻吩-2-甲基、噻吩-2-乙基和2-甲基吡啶基团的几种N-官能化双（膦酰基）胺配体（1a-e）。配体与 CH2Cl2 中的 (DME)NiBr2 反应得到相应的镍配合物 [Ph2PN(R)PPh2NiBr2] [R = CH2C6H5 (2a)、CH2C4H3O (2b)、CH2C4H3S (2c)、CH2C5H4N (2d) 和 CH2CH2C4H )]。这些配合物的结构是通过单晶 X 射线晶体学确定的。所有这些镍配合物在甲基铝氧烷或 Et2AlCl 存在下对乙烯低聚反应具有高度活性，产生高含量的丁烯 (C4)。特别是对于含有噻吩-2-乙基侧基的 2e，在 –40 °C 下获得的低聚产物含有 95.9 mol-% 的 C4 馏分和 100 mol-% 的 1-丁烯。然而，超过 50°C，
• trans- and cis-Ru(II) aminophosphine complexes: Syntheses, X-ray structures and catalytic activity in transfer hydrogenation of acetophenone derivatives
  作者：Murat Aydemir、Akın Baysal、Saim Özkar、Leyla Tatar Yıldırım

  DOI：10.1016/j.ica.2010.12.028

  日期：2011.2

  The ability of transition metal catalysts to add or remove hydrogen from organic substrates by transfer hydrogenation process is a valuable synthetic tool. For this aim, a novel Ru(II) complex with the P-N ligand [(Ph2P)(2)NCH2-C4H3S] derived from thiophene-2-methylamine was synthesized starting with the complex [Ru(eta(6)-p-cymene)(mu-Cl)Cl](2) and isolated in two isomeric forms: trans- and cis[Ru((PPh2)(2)NCH2-C4H3S)(2)Cl-2], 2 and 3, respectively. The structures of both isomers were also determined by single crystal X-ray diffraction. The cis-isomer 3 can be isolated from the solution of major trans-isomer 2 as yellow crystals. However, upon dissolution 3 is rapidly converted to the trans-isomer 2. The new ruthenium(II) complex provides high catalytic activity in the transfer hydrogenation of acetophenone derivatives to 1-phenylethanol derivatives in the presence of 2-propanol as the hydrogen source. This transfer hydrogenation is characterized by low reversibility under the experimental conditions. (C) 2010 Elsevier B.V. All rights reserved.
• LIGAND COMPOUND, CATALYST SYSTEM FOR OLEFIN OLIGOMERIZATION, AND OLEFIN OLIGOMERIZATION METHOD USING THE SAME
  申请人：LG CHEM, LTD.

  公开号：US20160271600A1

  公开（公告）日：2016-09-22

  The present invention relates to a ligand compound, a catalyst system for olefin oligomerization, and a method for olefin oligomerization using the same. The present ligand compound is a compound having a certain new structure and enables provision of a catalyst system for olefin oligomerization that can oligomerize ethylene with higher catalytic activity.