2-hydroxyethyl 2,6-dimethoxybenzoate | 13084-23-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-hydroxyethyl 2,6-dimethoxybenzoate
• 英文别名: 2.6-Dimethoxy-benzoesaeure-<2-hydroxy-aethylester>；2.6-Dimethoxy-benzoesaeure-(2-hydroxy-aethylester)
• CAS: 13084-23-6
• 化学式: C₁₁H₁₄O₅
• 分子量: 226.229
• InChiKey: VTYHERNUONCYCH-UHFFFAOYSA-N

物化性质

• 沸点：
  379.9±32.0 °C(Predicted)
• 密度：
  1.194±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  65
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2,6-二甲氧基苯甲酸 、 乙二醇 在 aluminum oxide 、 甲烷磺酸 作用下， 反应 0.25h， 以90%的产率得到2-hydroxyethyl 2,6-dimethoxybenzoate
  参考文献：
  名称：

  Al2O3/MeSO3H (AMA) as a new reagent with high selective ability for monoesterification of diols

  摘要：

  A new facile method for moncesterification of diols has been developed. A variety of diols, in particular oligoethylene glycols, were selectively monoesterified in excellent yields by reaction with aromatic and aliphatic acids in the presence Of Al2O3/MeSO3H as a new reagent without use of any solvents. (C) 2003 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4020(03)00518-0

文献信息

• Al2O3/MeSO3H (AMA) as a new reagent with high selective ability for monoesterification of diols
  作者：Hashem Sharghi、Mona Hosseini Sarvari

  DOI：10.1016/s0040-4020(03)00518-0

  日期：2003.5

  A new facile method for moncesterification of diols has been developed. A variety of diols, in particular oligoethylene glycols, were selectively monoesterified in excellent yields by reaction with aromatic and aliphatic acids in the presence Of Al2O3/MeSO3H as a new reagent without use of any solvents. (C) 2003 Elsevier Science Ltd. All rights reserved.