2-(benzo[b]thiophen-2-yl)-5-(di-(2-picolyl)aminomethyl)pyridine | 1314880-66-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻吩类
• 英文名称: 2-(benzo[b]thiophen-2-yl)-5-(di-(2-picolyl)aminomethyl)pyridine
• 英文别名: 2-(2'-benzo[b]thienyl)pyridine；1-[6-(1-benzothiophen-2-yl)pyridin-3-yl]-N,N-bis(pyridin-2-ylmethyl)methanamine
• CAS: 1314880-66-4
• 化学式: C₂₆H₂₂N₄S
• 分子量: 422.553
• InChiKey: XTXXZWPEFFWSQD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  31
• 可旋转键数：
  7
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  70.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  [iridium(III)(μ-chloro)(2-phenylpyridine)2]2 、 2-(benzo[b]thiophen-2-yl)-5-(di-(2-picolyl)aminomethyl)pyridine 在 CF₃SO₃Ag 作用下， 以 二乙二醇二甲醚 为溶剂， 以57%的产率得到
  参考文献：
  名称：

  Phosphorescent Sensor for Robust Quantification of Copper(II) Ion

  摘要：

  A phosphorescent sensor based on a multichromophoric iridium(III) complex was synthesized and characterized. The construct exhibits concomitant changes in its phosphorescence intensity ratio and phosphorescence lifetime in response to copper(II) ion. The sensor, which is reversible and selective, is able to quantify copper(II) ions in aqueous media, and it detects intracellular copper ratiometrically.

  DOI：

  10.1021/ja204997c
• 作为产物：
  描述：

  6-(benzo[b]thiophen-2-yl)nicotinaldehyde 、 二甲基吡啶胺 在 溶剂黄146 、 sodium cyanoborohydride 作用下， 以 甲醇 、 1,2-二氯乙烷 为溶剂， 反应 0.5h， 以49%的产率得到2-(benzo[b]thiophen-2-yl)-5-(di-(2-picolyl)aminomethyl)pyridine
  参考文献：
  名称：

  Phosphorescent Sensor for Robust Quantification of Copper(II) Ion

  摘要：

  A phosphorescent sensor based on a multichromophoric iridium(III) complex was synthesized and characterized. The construct exhibits concomitant changes in its phosphorescence intensity ratio and phosphorescence lifetime in response to copper(II) ion. The sensor, which is reversible and selective, is able to quantify copper(II) ions in aqueous media, and it detects intracellular copper ratiometrically.

  DOI：

  10.1021/ja204997c

文献信息

• Phosphorescent Sensor for Robust Quantification of Copper(II) Ion
  作者：Youngmin You、Yejee Han、Yong-Min Lee、Soo Young Park、Wonwoo Nam、Stephen J. Lippard

  DOI：10.1021/ja204997c

  日期：2011.8.3

  A phosphorescent sensor based on a multichromophoric iridium(III) complex was synthesized and characterized. The construct exhibits concomitant changes in its phosphorescence intensity ratio and phosphorescence lifetime in response to copper(II) ion. The sensor, which is reversible and selective, is able to quantify copper(II) ions in aqueous media, and it detects intracellular copper ratiometrically.