2-氯-6-甲基咪唑并[1,2-B]哒嗪 | 127566-20-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 中文名称: 2-氯-6-甲基咪唑并[1,2-B]哒嗪
• 中文别名: 2-氯-6-甲基咪唑并[1,2-b]吡嗪
• 英文名称: 2-Chloro-6-methylimidazo[1,2-b]pyridazine
• CAS: 127566-20-5
• 化学式: C₇H₆ClN₃
• mdl: MFCD11044775
• 分子量: 167.59
• InChiKey: JKZGZDGHCULMID-UHFFFAOYSA-N

物化性质

• 密度：
  1.43±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.142
• 拓扑面积：
  30.2
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2933990090

反应信息

• 作为产物：
  描述：

  1-(6-chloro-2-methylimidazo[1,2-b]pyridazin-3-yl)sulfonyl-3-(4-methoxy-6-methylpyrimidin-2-yl)urea 生成 2-氯-6-甲基咪唑并[1,2-B]哒嗪
  参考文献：
  名称：

  ISIDA, YASUO;OTA, KADZUNARI;NAKAXAMA, MATSUO;JOSIKAVA, XARUTOSI

  摘要：

  DOI：

文献信息

• PYRIDAZINONE COMPOUND OR ITS SALT, AND HERBICIDE CONTAINING IT
  申请人：ISHIHARA SANGYO KAISHA, LTD.

  公开号：US20200172517A1

  公开（公告）日：2020-06-04

  A novel herbicide having remarkable herbicidal activities against undesired plants is provided. A pyridazinone compound represented by the formula (I) or its salt: wherein X is —O—, —S—, —SO—, —SO 2 — or —N(Y)—; Q is monocyclic aryl which may be substituted by Z, monocyclic heteroaryl which may be substituted by Z or the like; Y is a hydrogen atom or alkyl; Z is halogen, alkyl or the like; R 1 is alkyl, alkenyl or the like; R 2 is a hydrogen atom, alkyl or the like; R 3 is halogen, hydroxy or the like; R 4 is a hydrogen atom, alkyl or the like; and n is an integer of from 0 to 4.

  提供了一种对不受欢迎的植物具有显著除草活性的新型除草剂。一种由以下式（I）或其盐表示的吡啶并酮化合物： 其中X为—O—，—S—，—SO—，—SO2—或—N(Y)—；Q为可以由Z取代的单环芳基，可以由Z取代的单环杂芳基或类似物；Y为氢原子或烷基；Z为卤素，烷基或类似物；R1为烷基，烯烃基或类似物；R2为氢原子，烷基或类似物；R3为卤素，羟基或类似物；R4为氢原子，烷基或类似物；n为0到4的整数。
• PHENOXYMETHYL HETEROCYCLIC COMPOUNDS
  申请人：ENVIVO PHAMACEUTICALS, INC.

  公开号：US20130143888A1

  公开（公告）日：2013-06-06

  Phenoxymethyl compounds that inhibit at least one phosphodiesterase 10 are described as are pharmaceutical compositions containing such compounds an methods for treating various CNS disorders by administering such compounds to a patient in need thereof.

  本文描述了抑制至少一种磷酸二酯酶10的苯甲氧基化合物，以及包含这些化合物的药物组合物和通过将这些化合物用于需要治疗的患者来治疗各种中枢神经系统疾病的方法。
• Pyridazinone compound or its salt, and herbicide containing it
  申请人：ISHIHARA SANGYO KAISHA, LTD.

  公开号：US10870638B2

  公开（公告）日：2020-12-22

  A novel herbicide having remarkable herbicidal activities against undesired plants is provided. A pyridazinone compound represented by the formula (I) or its salt: wherein X is —O—, —S—, —SO—, —SO2— or —N(Y)—; Q is monocyclic aryl which may be substituted by Z, monocyclic heteroaryl which may be substituted by Z or the like; Y is a hydrogen atom or alkyl; Z is halogen, alkyl or the like; R1 is alkyl, alkenyl or the like; R2 is a hydrogen atom, alkyl or the like; R3 is halogen, hydroxy or the like; R4 is a hydrogen atom, alkyl or the like; and n is an integer of from 0 to 4.

  本研究提供了一种新型除草剂，该除草剂对有害植物具有显著的除草活性。 一种由式（I）或其盐代表的哒嗪酮化合物： 其中 X 是-O-、-S-、-SO-、-SO2- 或-N(Y)-；Q 是可被 Z 取代的单环芳基、可被 Z 取代的单环杂芳基或类似物；Y 是氢原子或烷基；Z 是卤素、烷基或类似物；R1 是烷基、烯基或类似物；R2 是氢原子、烷基或类似物；R3 是卤素、羟基或类似物；R4 是氢原子、烷基或类似物；n 是 0 至 4 的整数。
• METHOD FOR PRODUCING IMIDAZO[1,2-b]PYRIDAZINE COMPOUND
  申请人：Sumitomo Chemical Company, Limited

  公开号：EP1930331B1

  公开（公告）日：2013-03-13
• PROCESS FOR PRODUCING IMIDAZO[1,2-b]PYRIDAZINE COMPOUND
  申请人：Komoto Ichiro

  公开号：US20100234597A1

  公开（公告）日：2010-09-16

  A process for producing an imidazo[1,2-b]pyridazine compound represented by the formula (2): wherein R 1 , R 2 and R 3 are the same or different and each represents a hydrogen atom, a halogen atom, an alkyl group which may be substituted with a halogen atom or atoms, an alkenyl group which may be substituted with a halogen atom or atoms, or an alkoxy group which may be substituted with a halogen atom or atoms, which comprises reacting a 2,3-dihydropyridazine compound represented by the formula (1): wherein R 1 , R 2 and R 3 are the same meanings as defined above, with a phosphorus oxyhalide in the presence of an organic base which is in an amount of 0.5 mole or more relative to 1 mole of the 2,3-dihydropyridazine compound and 1 mole or less relative to 1 mole of the phosphorus oxyhalide.