cis-1,2-bis-(2-pyridyl)-ethylene | 14802-37-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: cis-1,2-bis-(2-pyridyl)-ethylene
• 英文别名: (Z)-1,2-Bis-(2-pyridyl)-ethylen；cis-(2,2'-dipyridyl)ethylene；1,2-Bis(2-pyridyl)ethylene；2,2'-ethene-1,2-diyl-bis-pyridine；cis-1,2-di-[2]pyridyl-ethene；cis-1,2-Di-[2]pyridyl-aethen；cis-1,2-Bispyridylethylene；2-[(Z)-2-pyridin-2-ylethenyl]pyridine
• CAS: 14802-37-0
• 化学式: C₁₂H₁₀N₂
• 分子量: 182.225
• InChiKey: HKEOCEQLCZEBMK-FPLPWBNLSA-N

物化性质

• 沸点：
  346.6±0.0 °C(Predicted)
• 密度：
  1.145±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  cis-1,2-bis-(2-pyridyl)-ethylene 在 palladium on activated charcoal 氢气 作用下， 以 乙醇 为溶剂， 以93%的产率得到1,2-bis(pyridin-2-yl)ethane
  参考文献：
  名称：

  Lin, Ai Jeng, Organic Preparations and Procedures International, 1991, vol. 23, # 1, p. 114 - 115

  摘要：

  DOI：
• 作为产物：
  描述：

  (E)-1,2-双(2-吡啶基)乙烯 以 氯仿 为溶剂， 反应 1.0h， 以15%的产率得到cis-1,2-bis-(2-pyridyl)-ethylene
  参考文献：
  名称：

  Non-Covalent Assembly of a Photoswitchable Surface

  摘要：

  A noncovalently bound multilayered thin film in which individual layers are linked by metal ligand interactions undergoes a photochemically initiated permanent change in surface wettability. The film consists of three separate layers: a SAM on gold of 4-[(10-mercaptodecyl)oxy]pyridine-2,6-dicarboxylic acid, a layer of Cu(II) ions that are deposited onto the SAM and bind symmetrically in the site provided by the two carboxylate groups and the pyridyl nitrogen atom, and a layer of cis-2,2'-dipyridylethylene, which caps the Cu(II) layer by complexation through both pyridyl nitrogen atoms (Film I). Photoexcitation of the film in chloroform at 300 nm leads to substantial cis-trans isomerization as indicated by conductivity, impedance, grazing incidence IR, and contact angle measurements. The latter show a decrease in contact angle (increase in wettability) of 17 degrees , which is attributed to exposure of both the underlying Cu(II) layer and one of the pyridyl ring nitrogen atoms following isomerization to the trans isomer.

  DOI：

  10.1021/ja039230e

文献信息

• Eichinger, Karl; Berbalk, Hans; Winetzhammer, Willibald, Journal of Chemical Research, Miniprint, 1983, # 11, p. 2417 - 2429
  作者：Eichinger, Karl、Berbalk, Hans、Winetzhammer, Willibald

  DOI：——

  日期：——
• Azastilbenes. 2. Photodimerization
  作者：J. Vansant、S. Toppet、G. Smets、J. P. Declercq、G. Germain、M. Van Meerssche

  DOI：10.1021/jo01297a003

  日期：1980.4
• Jerchel; Melloh, Justus Liebigs Annalen der Chemie, 1959, vol. 622, p. 53,56
  作者：Jerchel、Melloh

  DOI：——

  日期：——
• KATRITZKY, ALAN R.;LAPUCHA, ANDRZEJ R.;SISKIN, MICHAEL, ENERGY AND FUELS , 4,(1990) N, C. 506-510
  作者：KATRITZKY, ALAN R.、LAPUCHA, ANDRZEJ R.、SISKIN, MICHAEL

  DOI：——

  日期：——
• [EN] METHOD OF TREATING HELICOBACTER PYLORI INFECTION<br/>[FR] PROCEDE DE TRAITEMENT DE L'INFECTION PROVOQUEE PAR HELICOBACTER PYLORI
  申请人：UNISEARCH LIMITED

  公开号：WO1994027606A1

  公开（公告）日：1994-12-08

  (EN) The present invention relates to a method of treating $i(Helicobacter pylori) infection. The method involves the administration of a composition, the active ingredient of which inhibits or prevents the action of fumarate reductase.(FR) Procédé de traitement de l'infection provoquée par $i(Helicobacter pylori), ce procédé consistant à administrer une composition dont l'ingrédient actif inhibe ou empêche l'action de la fumarate réductase.