N-4-bromomethylphenyl-N-ethylpivalamide | 111818-41-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-4-bromomethylphenyl-N-ethylpivalamide
• 英文别名: N-[4-(bromomethyl)phenyl]-N-ethyl-2,2-dimethylpropanamide
• CAS: 111818-41-8
• 化学式: C₁₄H₂₀BrNO
• 分子量: 298.223
• InChiKey: DAKQITSTOMSGOP-UHFFFAOYSA-N

物化性质

• 沸点：
  372.2±25.0 °C(Predicted)
• 密度：
  1.260±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  20.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1,3-二甲基-5-苯氧基吡唑-4-甲醛肟 、 N-4-bromomethylphenyl-N-ethylpivalamide 在 氢氧化钾 作用下， 以 水 、 二甲基亚砜 为溶剂， 以78%的产率得到N-4-[(1,3-dimethyl-5-phenoxypyrazol-4-yl)methyleneaminooxymethyl]phenyl-N-ethylpivalamide
  参考文献：
  名称：

  Pyrazole oxime derivatives and compositions

  摘要：

  一种由通式（I）表示的吡唑肟衍生物，可用作杀虫剂和杀菌剂，##STR1## 其中结构元素在规范中定义，并控制所述害虫的方法。通式（I）表示的化合物可以通过规范中披露的方法合成。

  公开号：

  US04843068A1

文献信息

• A pyrazole oxime derivative and its production and use
  申请人：NIHON NOHYAKU CO., LTD.

  公开号：EP0234045A2

  公开（公告）日：1987-09-02

  A pyrazole oxime derivative represented by the general formula (I) which is useful as an insecticide, mitecide and fungicide, wherein R' represents C1-C4 alkyl or phenyl; R2 represents hydrogen, C1-C5 alkyl, C1-C3 haloalkyl or phenyl; R3 represents hydrogen, C1-C4 alkyl gr phenyl; R4 represents hydrogen, CZ-C4 alkylcarbonyl, benzoyl, naphthyl or a substituent of the formula. [in which X represents hydrogen; halogen; C1-C12 alkyl; C1-C6 alkyl substituted with halogen, cyano, hydroxy, C1-C5 alkoxy or C2-C6 alkoxycarbonyl; C3-C8 cycloalkyl; cycloalkyl substituted with from one to three members selected from the group consisting of C1-C4 alkyl, halogen and cyano; C2-C4 alkenyl substituted with halogen, hydroxy, C2-C4 alkoxycarbonyl or C2-C6 alkylcarbonyl; phenyl; hydroxy; C1-C6 alkoxy; C1-C4 alkoxy substituted with halogen or C2-C6 alkoxycarbonyl; phenoxy which may or may not be substituted with C1-C3 haloalkyl benzyloxy; C1-C3 alkylenedioxy formed by two adjacent Xs; pyridyloxy which may or may not be substituted with halogen or C1-C3 haloalkyl; a substituent of the formula, -S(O)PR5 (in which R5 represents C1-C6 alkyl, C1-C5 haloalkyl or phenyl, and p represents an integer of 0, 1 or 2); cyano; formyl; nitro; a substituent of the formula -COORs (in which R6 represents hydrogen; alkali metal; C1-C10 alkyl; C1-C5 alkyl substituted with halogen, C,-C4 alkoxy, phenoxy, C2-C4 alkoxycarbonyl or phenoxyphenyl; C2-C7 alkenyl; C3-C7 alkynyl; C3-C8 cycloalkyl; C3-C8 cycloalkyl substituted with C1-C3 alkyl; phenyl; or a substituent of the formula, (in which R7, R8 and R9, which may be the same or different, represent C1-C4 alkyl or C3-C8 cycloalkyl)}; C2-C6 alkylcarbonyl; C2-C6 alkylcarbonyl substituted with cyano or C2-C6 alkoxycarbonyl; benzoyl which may or may not be substituted with halogen or C1-C6 alkyl; C2-C6 alkylthiocarbonyl; C3-C7 alkoxycarbonylcarbonyl; a substituent of the formula, (in which R10 and R", which may be the same or different, represent hydrogen, C1-C6 alkyl or phenyl); piperidinocarbonyl; morpholinocarbonyl which may or may not be substituted with one or two C1-C4 alkyls; a substituent of the formula, (in which R12 represents hydrogen or C1-C5 alkyl, and R13 represents formyl, C2-C12 alkoxycarbonyl, or C2-CS alkoxycarbonyl substituted with halogen or C1-C4 alkoxy); a substituent of the formula, (in which R14 represents hydrogen, C1-C4 alkyl or C2-C6 alkoxyalkyl); a substituent of the formula, (in which R15 and R16, which may be the same or different, represent C1-C4 alkyl, or taken together, may form C1-C4 alkylene, R17 represents C1-C5 alkyl, cyano or C2-C6 alkoxycarbonyl, and B represents oxygen or sulfur); a substituent of the formula, (in which R18 represents hydrogen or C2-C4 alkylcarbonyl, and R19 and R20, which may be the same or different, represent hydrogen or C1-C6 alkyl); a substituent of the formula, (in which R21, R22 and R23, which may be the same or different, represent C1-C4 alkyl); or a substituent of the formula, (in which R24, R25 and R26, which may be the same or different, represent C1-C4 alkyl), and n represents an integer of from 1 to 5, and when n represents an integer of from 2 to 5, X may be the same or different ]; Y represents hydrogen, C1-C6 alkyl, C1-C4 haloalkyl, halogen, hydroxy, C,-C4 alkoxy, C1-C4 haloalkoxy, C1-C3 alkylenedioxy, phenoxy which may or may not be substituted with trifluoromethyl, a substistuent of the formula, -S(Q)qR27 (in which R27 represents C1-C3 alkyl and q represents an integer of 0, 1 or 2), hydroxycarbonyl, C2-C5 alkoxycarbonyl or a substituent of the formula, (in which R28 and R29, which may be the same or different, represent hydrogen, C1-C4 alkyl, or benzyl which may or may not be substituted with C2-C6 alkoxycarbonyl); Z' represents oxygen or sulfur; Z2 represents oxygen, sulfur or single bond; Q represents C1-C8 alkylene, C1-C8 alkylene substituted with halogen or phenyl, C3-C12 alkenylene, C3-C12 haloalkenylene or C3-C6 alkynylene; and m represents an integer of from 1 to 3, and when m represents an integer of 2 or 3, Y may be the same or different; and the method of controlling said pests by using the same oxime derivative.

  由通式(I)代表的吡唑肟衍生物，可用作杀虫剂、杀螨剂和杀真菌剂、 其中 R' 代表 C1-C4 烷基或苯基；R2 代表氢、C1-C5 烷基、C1-C3 卤代烷基或苯基；R3 代表氢、C1-C4 烷基格苯基；R4 代表氢、CZ-C4 烷基羰基、苯甲酰基、萘基或式中的取代基。 [其中 X 代表氢；卤素；C1-C12 烷基；被卤素、氰基、羟基、C1-C5 烷氧基或 C2-C6 烷氧基羰基取代的 C1-C6 烷基；C3-C8 环烷基；被选自 C1-C4 烷基、卤素和氰基的一至三个成员取代的环烷基；被卤素、羟基、C2-C4 烷氧基羰基或 C2-C6 烷基羰基取代的 C2-C4 烯基；苯基；羟基；C1-C6 烷氧基；被卤素或 C2-C6 烷氧基羰基取代的 C1-C4 烷氧基；可以被或不可以被 C1-C3 卤代烷基苄氧基取代的苯氧基；由两个相邻 X 形成的 C1-C3 亚烷基二氧基；可以或不可以被卤素或 C1-C3 卤代烷基取代的吡啶氧基；式 -S(O)PR5 的取代基（其中 R5 代表 C1-C6 烷基、C1-C5 卤代烷基或苯基，p 代表 0、1 或 2 的整数）；氰基；甲酰基；硝基；式 -COORs 的取代基（其中 R6 代表氢；碱金属；C1-C10 烷基；被卤素、C,-C4 烷氧基、苯氧基、C2-C4 烷氧羰基或苯氧基取代的 C1-C5 烷基；C2-C7 烯基；C3-C7 炔基；C3-C8 环烷基；被 C1-C3 烷基取代的 C3-C8 环烷基；苯基；或式-COORs 的取代基（其中 R7、R8 代表氢）、 (其中R7、R8和R9可以相同或不同，代表C1-C4烷基或C3-C8环烷基）}；C2-C6烷基羰基；被氰基或C2-C6烷氧基羰基取代的C2-C6烷基羰基；可以或不可以被卤素或C1-C6烷基取代的苯甲酰基；C2-C6烷硫基羰基；C3-C7烷氧基羰基羰基；式中的取代基、 (其中R10和R "可以相同或不同，代表氢、C1-C6烷基或苯基）； 哌啶羰基；吗啉羰基，可以或不可以被一个或两个C1-C4烷基取代； 式中的取代基、 (其中 R12 代表氢或 C1-C5 烷基，R13 代表甲酰基、C2-C12 烷氧基羰基或被卤素或 C1-C4 烷氧基取代的 C2-CS 烷氧基羰基）；式中的取代基、 (其中 R14 代表氢、C1-C4 烷基或 C2-C6 烷氧基烷基)；式中的一个取代基、 (式中，R15 和 R16 可相同或不同，代表 C1-C4 烷基，或合在一起可形成 C1-C4 亚烷基，R17 代表 C1-C5 烷基、氰基或 C2-C6 烷氧羰基，B 代表氧或硫、 (其中 R18 代表氢或 C2-C4 烷基羰基，R19 和 R20（可相同或不同）代表氢或 C1-C6 烷基）；式中的取代基、 (其中 R21、R22 和 R23 可相同或不同，代表 C1-C4 烷基）；或式中的取代基、 (其中 R24、R25 和 R26（可以相同或不同）代表 C1-C4 烷基），且 n 代表 1 至 5 的整数，当 n 代表 2 至 5 的整数时，X 可以相同或不同 ]；Y 代表氢、C1-C6 烷基、C1-C4 卤代烷基、卤素、羟基、C,-C4 烷氧基、C1-C4 卤代烷氧基、C1-C3 二烷氧基、可以或不可以被三氟甲基取代的苯氧基、式中的取代基、-S(Q)qR27（其中 R27 代表 C1-C3 烷基，q 代表 0、1 或 2 的整数）、羟基羰基、C2-C5 烷氧基羰基或式中的取代基、 (其中 R28 和 R29 可以相同或不同，分别代表氢、C1-C4 烷基或可以被或不被 C2-C6 烷氧羰基取代的苄基）；Z' 代表氧或硫；Z2 代表氧、硫或单键；Q代表C1-C8亚烷基、被卤素或苯基取代的C1-C8亚烷基、C3-C12烯基、C3-C12卤代烯基或C3-C6炔基；以及m代表1至3的整数，当m代表2或3的整数时，Y可以相同或不同；以及通过使用相同的肟衍生物来控制所述害虫的方法。
• US4843068A
  申请人：——

  公开号：US4843068A

  公开（公告）日：1989-06-27
• Pyrazole oxime derivatives and compositions
  申请人：Nihon Nohyaku Co., Ltd.

  公开号：US04843068A1

  公开（公告）日：1989-06-27

  A pyrazole oxime derivative represented by the general formula (I) which is useful as an insecticide and fungicide, ##STR1## wherein the structural elements are defined in the specification, and the method of controlling said pests. The compounds represented by the general formula (I) can be synthesized by the methods disclosed in the specification.

  一种由通式（I）表示的吡唑肟衍生物，可用作杀虫剂和杀菌剂，##STR1## 其中结构元素在规范中定义，并控制所述害虫的方法。通式（I）表示的化合物可以通过规范中披露的方法合成。