4-[N'-(4-Aminophenyl)ureido]benzoic acid | 227598-05-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-[N'-(4-Aminophenyl)ureido]benzoic acid
• 英文别名: 4-[(4-Aminophenyl)carbamoylamino]benzoic acid
• CAS: 227598-05-2
• 化学式: C₁₄H₁₃N₃O₃
• 分子量: 271.276
• InChiKey: NEAUMGOQJRBYIK-UHFFFAOYSA-N

物化性质

• 熔点：
  256 °C
• 沸点：
  420.6±30.0 °C(Predicted)
• 密度：
  1.468±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  104
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-[N'-(4-Aminophenyl)ureido]benzoic acid 、 己二酰氯 在 三乙胺 作用下， 以 N-甲基吡咯烷酮 为溶剂， 反应 24.0h， 以80%的产率得到4,4'-(((((adipoylbis(azanediyl))bis(4,1-phenylene))bis(azanediyl))bis(carbonyl)) bis(azanediyl))dibenzoic acid
  参考文献：
  名称：

  Bis amide-aromatic-ureas—highly effective hydro- and organogelator systems

  摘要：

  A series of hydro- and organo-supergelators have been synthesised via coupling of simple bis aromatic-ureas via alkyl amide linkages. These bis amide-aromatic-ureas exhibited reduced critical gelator concentrations, improved gelator stability, mechanical and dye removal properties for potential use in water purification, in comparison to related bis aromatic-ureas. Systematic structure studies via variation of the bis amide-aromatic-urea linker length as well as functionalization of the terminal aromatic moieties have enabled control over the gel properties. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2014.09.017

文献信息

• US6187285B1
  申请人：——

  公开号：US6187285B1

  公开（公告）日：2001-02-13
• Bis amide-aromatic-ureas—highly effective hydro- and organogelator systems
  作者：B.C. Baker、A.L. Acton、G.C. Stevens、W. Hayes

  DOI：10.1016/j.tet.2014.09.017

  日期：2014.11

  A series of hydro- and organo-supergelators have been synthesised via coupling of simple bis aromatic-ureas via alkyl amide linkages. These bis amide-aromatic-ureas exhibited reduced critical gelator concentrations, improved gelator stability, mechanical and dye removal properties for potential use in water purification, in comparison to related bis aromatic-ureas. Systematic structure studies via variation of the bis amide-aromatic-urea linker length as well as functionalization of the terminal aromatic moieties have enabled control over the gel properties. (C) 2014 Elsevier Ltd. All rights reserved.