2-溴-5-(苯基硫代)吡嗪 | 767342-33-6

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 中文名称: 2-溴-5-(苯基硫代)吡嗪
• 英文名称: 2-bromo-5-phenylsulfanyl-pyrazine
• 英文别名: 2-Bromo-5-(phenylthio)pyrazine；2-bromo-5-phenylsulfanylpyrazine
• CAS: 767342-33-6
• 化学式: C₁₀H₇BrN₂S
• 分子量: 267.149
• InChiKey: MFOPNDSLEFEENV-UHFFFAOYSA-N

物化性质

• 沸点：
  379.4±42.0 °C(Predicted)
• 密度：
  1.63±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  51.1
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• [EN] COMPOUND LIBRARIES<br/>[FR] BIBLIOTHEQUE DE COMPOSES
  申请人：BIOFOCUS DISCOVERY LTD

  公开号：WO2004085409A2

  公开（公告）日：2004-10-07

  The present invention relates to pyridine,pyrazine,imidoz[1,2a]pyrazine and 1H-imidoz[4,5-b]pyrazin-2-one compounds capable of binding to the active site of protein kinase enzymes. The invention further relates to libraries of these compounds and a family of libraries of these compounds for use in screening programmes against protein kinases as well as the individual compounds for use in hit to lead and lead optimisation projects, and similar stages in the drug discovery process. The invention also provides methods for making compounds and libraries, thereof.