N-phenylthiazole-2-carboxamide | 16733-88-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-phenylthiazole-2-carboxamide
• 英文别名: N-phenylthiazole-4-carboxamide；Thiazol-carbonsaeure-(2)-anilid；Thiazol-2-carbonsaeure-anilid；N-Phenylthiazol-2-carboxamid；thiazole-2-carboxylic acid anilide；Thiazole carboxanilide；N-phenyl-1,3-thiazole-2-carboxamide
• CAS: 16733-88-3
• 化学式: C₁₀H₈N₂OS
• 分子量: 204.252
• InChiKey: FOOHWUQIWMQCQA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  70.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-phenylthiazole-2-carboxamide 在 盐酸 作用下， 以 乙醇 为溶剂， 生成 N-thiazol-2-ylmethyl-aniline
  参考文献：
  名称：

  Iversen,P.E.; Lund,H., Acta Chemica Scandinavica (1947), 1967, vol. 21, p. 389 - 396

  摘要：

  DOI：
• 作为产物：
  描述：

  噻唑-2-甲酸 、 苯胺 在 氯甲酸乙酯 作用下， 生成 N-phenylthiazole-2-carboxamide
  参考文献：
  名称：

  Iversen,P.E.; Lund,H., Acta Chemica Scandinavica (1947), 1967, vol. 21, p. 389 - 396

  摘要：

  DOI：

文献信息

• HETEROCYCLIC CARBOXYLIC ACID AMIDE LIGAND AND APPLICATIONS THEREOF IN COPPER CATALYZED COUPLING REACTION OF ARYL HALOGENO SUBSTITUTE
  申请人：CE Pharm CO., LTD.

  公开号：US20190127337A1

  公开（公告）日：2019-05-02

  Provided are a heterocyclic carboxylic acid amide ligand and applications thereof in a copper catalyzed coupling reaction. Specifically, provided are uses of a compound represented by formula (I), definitions of radical groups being described in the specifications. The compound represented by formula (I) can be used as the ligand in the copper catalyzed coupling reaction of the aryl halogeno substitute, and is used or catalyzing the coupling reaction for forming the aryl halogeno substitute having C—N, C—O, C—S and other bonds.

  提供了一种杂环羧酸酰胺配体及其在铜催化的偶联反应中的应用。具体地，提供了一种由公式(I)表示的化合物的用途，其中自由基组的定义在说明书中有所描述。由公式(I)表示的化合物可作为铜催化偶联反应中芳基卤素取代物的配体，并用于催化形成具有C-N、C-O、C-S等键的芳基卤素取代物的偶联反应。
• Improved process for the preparation of 2-methylthiazole-5-carboxylates
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0650963A1

  公开（公告）日：1995-05-03

  An improved process for the preparation of alkyl 4-halomethyl-2-methylthiazole-5-carboxylate comprising contacting a solution of alkyl 4-(halo)-2-chloroacetoacetate in acetonitrile with thioacetamide in the presence of an amine, such as triethylamine.

  一种改进的制备烷基4-卤甲基-2-甲基噻唑-5-羧酸酯的方法，包括将烷基4-(卤)-2-氯乙酰乙酸酯的溶液与硫代乙酰胺在胺的存在下（如三乙胺）在乙腈中接触。
• ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF
  申请人：Soll Mark David

  公开号：US20140080862A1

  公开（公告）日：2014-03-20

  The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives of formula (I): wherein R 3 , R 4 , R 5 , R 6 , R 7 , P, Q, V, W, X, Y, Z and a are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.

  本发明涉及新颖的式(I)的芳基咪唑-2-基-氰基乙基氨基衍生物：其中R3、R4、R5、R6、R7、P、Q、V、W、X、Y、Z和a如描述中所定义，以及其组合物、制备方法以及它们作为杀虫剂的用途。
• 1-Aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof
  申请人：Lee Ik Hyoung

  公开号：US20080031902A1

  公开（公告）日：2008-02-07

  Provided are 1-aryl-5-alkyl pyrazole compounds, of formula (I): wherein: R 1 is hydrogen, cyano, halogen, R 8 , formyl, —C(O)R 8 , —C(O)OR 8 , —C(O)NR 9 R 10 , or —C(S)NH 2 ; R 2 is R 2 or —S(O) m R 11 ; R 3 is methyl, ethyl or C 1 -C 4 haloalkyl; R 4 , R 5 and R 7 are independently hydrogen, halogen, alkyl, haloalkyl, cyano or nitro; R 6 is halogen, alkyl, haloalkyl, alkoxy, haloalkyloxy, cyano, nitro, —C(O)R 12 , —S(O) n R 12 or SF 5 ; Z is a nitrogen atom or C—R 13 ; R 8 is alkyl, haloalkyl, cycloalkyl or halocycloalkyl; R 9 is hydrogen, alkyl, haloalkyl or alkoxy; R 10 is hydrogen, alkyl, haloalkyl or alkoxy; R 11 is alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl or cycloalkyl; R 12 is alkyl or haloalkyl; R 13 is hydrogen, halogen, cyano, nitro, alkyl, haloalkyl, alkoxy or haloalkoxy; m is 0, 1 or 2; and n is 0, 1 or 2; or a salt thereof, the method of making compounds of formula (I) and the use of these compounds against ectoparasites, endoparasites and pests.

  提供了1-芳基-5-烷基吡唑化合物，化学式为(I)：其中：R1为氢、氰基、卤素、R8、甲酰基、—C(O)R8、—C(O)OR8、—C(O)NR9R10或—C(S)NH2；R2为R2或—S(O)mR11；R3为甲基、乙基或C1-C4卤代烷基；R4、R5和R7独立地为氢、卤素、烷基、卤代烷基、氰基或硝基；R6为卤素、烷基、卤代烷基、烷氧基、卤代烷氧基、氰基、硝基、—C(O)R12、—S(O)nR12或SF5；Z为氮原子或C—R13；R8为烷基、卤代烷基、环烷基或卤代环烷基；R9为氢、烷基、卤代烷基或烷氧基；R10为氢、烷基、卤代烷基或烷氧基；R11为烷基、卤代烷基、烯基、卤代烯基、炔基、卤代炔基或环烷基；R12为烷基或卤代烷基；R13为氢、卤素、氰基、硝基、烷基、卤代烷基、烷氧基或卤代烷氧基；m为0、1或2；n为0、1或2；或其盐，制备化合物(I)的方法以及这些化合物对外寄生虫、内寄生虫和害虫的用途。
• Synergistic biocidal composition
  申请人：——

  公开号：US20030199490A1

  公开（公告）日：2003-10-23

  The invention relates to a biocidal composition which can be added to materials which can be attacked by harmful micro-organisms, containing pyrithione as a biocidal active ingredient. The biocidal composition is characterised in that it contains 2-alkyl isothiazoline-3-one as another biocidally active ingredient. The active ingredients of the biocidal composition behave synergistically and are ideally suitable for controlling bacteria, fungus and algae.

  本发明涉及一种生物杀菌组成物，可添加到可能被有害微生物侵害的材料中，其中含有吡啶硫酮作为生物杀菌活性成分。该生物杀菌组成物的特点在于其含有2-烷基异噻唑啉-3-酮作为另一种具有生物杀菌活性的成分。该生物杀菌组成物的活性成分表现出协同作用，非常适合控制细菌、真菌和藻类。