1-[(1R,2S,5R,7R,8S)-2-hydroxy-8-phenylmethoxy-5-(phenylmethoxymethyl)-6-oxabicyclo[3.2.1]octan-7-yl]-5-methylpyrimidine-2,4-dione 、
2-氯-5-甲基苯甲醛 在
吡啶 作用下,
以90%的产率得到[(1R,2S,5R,7R,8S)-7-(5-methyl-2,4-dioxopyrimidin-1-yl)-8-phenylmethoxy-5-(phenylmethoxymethyl)-6-oxabicyclo[3.2.1]octan-2-yl] 4-methylbenzoate