thioisobutyric acid O-ethyl ester | 13806-76-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 硫代羧酸及其衍生物
• 英文名称: thioisobutyric acid O-ethyl ester
• 英文别名: Monothioisobuttersaeure-aethylester；Ethyl thioisobutyrate；O-ethyl 2-methylpropanethioate
• CAS: 13806-76-3
• 化学式: C₆H₁₂OS
• 分子量: 132.227
• InChiKey: AOLNPQXLMJDZHS-UHFFFAOYSA-N

物化性质

• 沸点：
  140.3±23.0 °C(Predicted)
• 密度：
  0.949±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  41.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  thioisobutyric acid O-ethyl ester 在 盐酸羟胺 、 sodium methylate 作用下， 生成 Isobutyrothiohydroxamsaeure
  参考文献：
  名称：

  Mizukami,S.; Nagata,K., Chemical and pharmaceutical bulletin, 1966, vol. 14, p. 1249 - 1255

  摘要：

  DOI：
• 作为产物：
  描述：

  ethyl isobutyrimidate hydrochloride 在 吡啶 、 硫化氢 作用下， 生成 thioisobutyric acid O-ethyl ester
  参考文献：
  名称：

  Mizukami,S.; Nagata,K., Chemical and pharmaceutical bulletin, 1966, vol. 14, p. 1249 - 1255

  摘要：

  DOI：

文献信息

• Resin composition for coating optical fiber and coated optical fiber and optical fiber unit using the same
  申请人：Dainippon Ink and Chemicals, Inc.

  公开号：US20030138231A1

  公开（公告）日：2003-07-24

  A resin composition for an optical fiber is provided which can be sufficiently cured even in high-speed processing (at a low light energy dose) to obtain a cured article having a Young's modulus suitable for use for an optical fiber, and also causes neither increase in viscosity nor deposition of solids in storage for a long period or in storage at a high temperature and can be easily coated even after such storage. A coated fiber and an optical fiber unit, which use the resin composition are also provided. The composition contains a radical polymerizable compound (A); a photopolymerization initiator (B); a sulfide (C) represented by the formulas: R 1 —S—R 1 , R 2 OOCCH 2 CH 2 —S—CH 2 CH 2 COOR 2 , (R 3 —SCH 2 CH 2 COOCH 2 ) 4 C, HOCH 2 CH 2 S—R 4 —SCH 2 CH 2 OH, 1 R 8 —SCH 2 CH 2 COOR 9 ; and an organic amine (D) represented by the formula: 2

  提供了一种用于光纤的树脂组合物，即使在高速处理（低光能剂量）时也可以充分固化，以获得适用于光纤的杨氏模量的固化物，并且在长期储存或高温储存时既不会增加粘度也不会沉淀固体，并且即使在这样的储存后也可以轻松涂层。提供了使用该树脂组合物的涂覆纤维和光纤单元。该组合物包含以下成分：自由基聚合性化合物（A）；光聚合引发剂（B）；硫化物（C），其由以下公式表示：R1—S—R1、R2OOCCH2CH2—S—CH2CH2COOR2、（R3—SCH2CH2COOCH2）4C、HOCH2CH2S—R4—SCH2CH2OH、1R8—SCH2CH2COOR9；以及有机胺（D），其由以下公式表示：2。
• QUINOLINE DERIVATIVE OR SALT THEREOF AND REMEDY FOR CARDIAC DISEASES CONTAINING THE SAME
  申请人：KOWA CO. LTD.

  公开号：EP0638571A1

  公开（公告）日：1995-02-15

  A quinoline derivative represented by general formula (1), a medicinally acceptable salt thereof, and a remedy for cardiac diseases containing the same, wherein ring A represents a furan, dihydrofuran or dioxolane ring, R¹ represents hydroxy, carboxy, alkoxycarbonyl, etc., R²s may be the same or different from each other and each represents hydrogen, alkyl, etc., R³ and R⁴ may be the same or different from each other and each represents hydrogen, halogen, alkyl, amino, alkoxy, etc., R⁵, R⁶, R⁷ and R⁸ may be the same or different from one another and each represents hydrogen or alkyl, m represents an integer of 0 to 3, and symbol ...... means that there may be a double bond formed by R⁶ and R⁸. The compound (1) has a positively inotropic effect on myocardia and an antiarrhythmic effect and can dilate blood vessels without extremely increasing the heart rate. Therefore, a remedy for cardiac diseases containing the same as the active ingredient is remarkably useful for treating cardiac insufficiency, arrhythmia, and so forth.

  一种由通式(1)代表的喹啉衍生物、其药用盐以及含有该衍生物的治疗心脏病的药物，其中环A代表呋喃、二氢呋喃或二氧戊环，R¹代表羟基、羧基、烷氧羰基等，R²s可以相同或不同，各自代表氢、烷基等、R³ 和 R⁴ 可以相同或互不相同，各自代表氢、卤素、烷基、氨基、烷氧基等，R⁵、R⁶、R⁷ 和 R⁸ 可以相同或互不相同，各自代表氢或烷基，m 代表 0 至 3 的整数，符号 ...... 表示 R⁶ 和 R⁸ 可以形成双键。化合物(1)对心肌具有正性肌力作用和抗心律失常作用，并能扩张血管而不会极度增加心率。因此，以该化合物为有效成分的心脏疾病治疗药物对治疗心功能不全、心律失常等有显著作用。
• Curable composition, thermal latent acid catalyst, method of coating, coated article, method of molding and molded article
  申请人：NOF CORPORATION

  公开号：EP0643112A2

  公开（公告）日：1995-03-15

  57 A curable composition comprising (A) a compound having in the molecule two or more specific blocked carboxyl groups; (B) a compound having in the molecule two or more reactive functional groups which can form chemical bonds with the blocked carboxyl groups, and (C) a catalitic component selected from the group sonsisting of a thermal latent acid catalyst which comprises (a) (i) a compound having a epoxy group, (ii) a specific compound having a sulfur atom and (iii) a specific Lewis acid; a thermal latent acid catalyst which comprises (b) (v) a specific compound having at least one selected from the group consisting of a nitrogen atom, an oxygen atom, a phosphorus atom and a sulfur atom, (vi) a specific compound having a halogen atom and (vii) a specific Lewis acid having at least one selected from the group consisting of an aluminium atom, a zinc atom and a tin atom; and a mixture which comprises (c) (viii) a metallic chelate compound and (ix) a specific organic silicon compound or the condensate. A two component curable composition is prepared by mixing (I) a main material composition or a solution thereof comprising the compound (A) and the compound (B) or the self-crosslinkable compound (D), and (II) an acid catalyst or the solution comprising at least one kind selected from the group consisting of a Br q) nsted acid, a Lewis acid and a mixture of a metallic chelate compound and a compound having a silanol group.The curable composition of the invention gives cured products having excellent chemical properties, physical properties, weathering resistance, stain resistance and excellent appearance.

  57 一种可固化组合物，包括(A)分子中具有两个或两个以上特定封端羧基的化合物；(B)分子中具有两个或两个以上可与封端羧基形成化学键的活性官能团的化合物，以及(C)选自以下组别的催化组分：热潜酸催化剂，包括(a)(i)具有环氧基团的化合物，(ii)具有硫原子的特定化合物和(iii)特定路易斯酸；一种热潜伏酸催化剂，它包括(b)(v)一种特定化合物，其中至少有一种选自氮原子、氧原子、磷原子和硫原子组成的组，(vi)一种特定化合物，其中至少有一种选自卤素原子，(vii)一种特定路易斯酸，其中至少有一种选自铝原子、锌原子和锡原子组成的组；以及一种混合物，它包括(c)(viii)一种金属螯合物和(ix)一种特定有机硅化合物或其缩合物。双组分可固化组合物的制备方法是将(I)主材料组合物或其溶液（包括化合物(A)和化合物(B)或自交联化合物(D)）和(II)酸催化剂或溶液（包括至少一种选自 Br q) nsted 酸、路易斯酸和金属螯合物与具有硅烷醇基的化合物的混合物）混合在一起。
• Curable base-coat composition, method of film-forming and coated articles
  申请人：NOF CORPORATION

  公开号：EP0709415A2

  公开（公告）日：1996-05-01

  A curable base-coat composition which comprises (1) a resin component essentially consisting of a polymer of an ethylenically unsaturated monomer having 500 to 4,000 of an epoxy equivalent, 10 to 200 of a hydroxyl value, ―30 to 80°C of a glass transition temperature and 3,000 to 150,000 of a weight average molecular weight, (2) a curing agent having two or more functional groups in the molecular which can react with the hydroxyl groups of the resin component (1), (3) a Lewis acid catalyst, and (4) a pigment selected from the group consisting of a color pigment and a bright pigment. The curable base-coat composition has adhesive active points to curable clear-coat compositions comprising the acid curing agents blocked chemically and the resins containing epoxy groups or curable clear-coat compositions of the polyol-melamine type and/or the polyol-melamine-polyisocyanate type and gives a cured film having excellent cured film properties. The curable base-coat composition sufficiently exert the excellent characteristics of curable clear-coat compositions.

  一种可固化的底层涂料组合物，它包括：(1) 一种树脂组分，主要由乙烯不饱和单体的聚合物组成，其环氧当量为 500 至 4000，羟基值为 10 至 200，玻璃化温度为-30 至 80°C，重量平均分子量为 3000 至 150、(2) 一种固化剂，其分子中含有两个或两个以上可与树脂组分 (1) 的羟基反应的官能团；(3) 一种路易斯酸催化剂；以及 (4) 一种颜料，选自彩色颜料和亮光颜料组成的组。这种可固化基涂层组合物对由化学封锁的酸固化剂和含有环氧基团的树脂组成的可固化清漆组合物或多元醇-三聚氰胺型和/或多元醇-三聚氰胺-多异氰酸酯型可固化清漆组合物具有粘合活性点，并能生成具有优异固化膜性能的固化膜。可固化基涂层组合物充分发挥了可固化透明涂层组合物的优异特性。
• THERMOSETTING COMPOSITION, METHOD OF FINISH COATING, AND COATED ARTICLES
  申请人：NOF CORPORATION

  公开号：EP0774476A1

  公开（公告）日：1997-05-21

  A thermosetting composition which comprises (A) an epoxy group-containing modified polyester polymer comprising a structural moiety of (a) a carboxyl group-containing polyester resin having a number average molecular weight of 1,500 to 50,000 and a resin acid value of 2 to 30 mgKOH/g and a structural moiety of a polymer of (b) an epoxy group-containing vinyl monomer, the carboxyl groups and a part of the epoxy groups being bonded in an equivalent ratio of the carboxyl groups in the component (a) to the epoxy groups in the polymer of the component (b) of 0.1 or less, and having an epoxy equivalent weight of 200 to 2,000 g/mol, and (B) a compound having two or more functional groups which are blocked by a vinyl ether, vinyl thioether or heterocyclic group carrying oxygen or sulfur as the heteroatom and having a double bond of the vinyl type. The composition can give cured articles excellent in hardness, chemical resistance, stain resistance, processability, impact resistance, elasticity and weathering resistance and has a good storage stability.

  一种热固性组合物，它包括(A)含环氧基的改性聚酯聚合物，其结构分子为(a)含羧基的聚酯树脂，其平均分子量为1 500至50、000 和树脂酸值为 2 至 30 mgKOH/g 的含羧基的聚酯树脂的结构分子和 (b) 含环氧基的乙烯基单体的聚合物的结构分子，羧基和部分环氧基以组分 (a) 中的羧基与组分 (b) 的聚合物中的环氧基的当量比 0.1 或更低，且环氧当量重量为 200 至 2,000 克/摩尔，以及 (B) 具有两个或两个以上官能团的化合物，这些官能团被乙烯基醚、乙烯基硫醚或杂环基封堵，杂环基以氧或硫作为杂原子，并具有乙烯基类型的双键。这种组合物可以使固化物具有优异的硬度、耐化学性、抗污性、可加工性、抗冲击性、弹性和耐候性，并具有良好的储存稳定性。