4-vinylbenzyldimethylammonio propanesulfonate | 172530-02-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-vinylbenzyldimethylammonio propanesulfonate
• 英文别名: 3-[(4-Ethenylphenyl)methyl-dimethylazaniumyl]propane-1-sulfonate
• CAS: 172530-02-8
• 化学式: C₁₄H₂₁NO₃S
• 分子量: 283.392
• InChiKey: KWTGXHDPIPNNHP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  65.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4-氯甲基苯乙烯 以 乙醇 、 水 、 乙腈 为溶剂， 反应 66.0h， 生成 4-vinylbenzyldimethylammonio propanesulfonate
  参考文献：
  名称：

  Synthesis of a series of monomeric styrene sulfobetaine precursors

  摘要：

  Procedures for the synthesis of five sulfobetaine monomers as styrene derivatives are given. The five molecules form a homologous row differing in the distance between the inner quaternary amine and the outer sulfonic acid from one methylene group to five methylene groups. Syntheses are achieved by a sequence of nucleophilic substitutions starting from commercially available precursors. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.12.100

文献信息

• [EN] POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT<br/>[FR] COMPOSÉS TRICYCLIQUES FUSIONNÉS POLYMÉRISABLES EN TANT QU'ABSORBEURS DE LUMIÈRE UV ET VISIBLE
  申请人：JOHNSON & JOHNSON VISION CARE

  公开号：WO2020261021A1

  公开（公告）日：2020-12-30

  Described are polymerizable fused tricyclic compounds of formula I: wherein R1, R2, R3, m, n, t, and rings B, C, and D are as defined herein. The compounds absorb various wavelengths of ultraviolet and/or visible light (such as high energy visible light) and are suitable for incorporation in a variety of products, such as biomedical devices and ophthalmic devices.

  描述了公式I的可聚合的融合三环化合物，其中R1、R2、R3、m、n、t和环B、C和D的定义如本文所述。这些化合物吸收各种紫外线和/或可见光波长（如高能可见光），适用于各种产品中，如生物医学器械和眼科器械。
• Chemically Triggered Coalescence and Reactivity of Droplet Fibers
  作者：Jing Zhao、Zehao Pan、Deborah Snyder、Howard A. Stone、Todd Emrick

  DOI：10.1021/jacs.1c02576

  日期：2021.4.14

  pendent groups were synthesized for stabilization of oil-in-water droplets, in which the self-adherent properties of the selected zwitterions impart interdroplet adherence, while the amine groups provide access to pH-triggered coalescence. Macroscopic fibers, obtained by droplet extrusion, were prepared with reagents embedded in spatially distinct components of the fibers. Upon acidification of the

  我们描述了功能性聚合物表面活性剂在液滴基纤维的构造和引发塌陷中的作用，以及这些宏观超胶体结构在试剂分隔中的用途。合成了含有两性离子和叔胺侧基的共聚物表面活性剂，用于稳定水包油液滴，其中所选两性离子的自粘附特性赋予液滴间粘附，而胺基团提供了 pH 触发聚结的途径。通过液滴挤出获得的宏观纤维是用嵌入纤维空间不同成分中的试剂制备的。当连续水相酸化时，聚合物表面活性剂的质子化增加了它们的亲水性并导致纤维快速破裂和塌陷。这些超胶体纤维的交联版本在酸化后是稳定的，并且似乎可以沿着纤维长度引导封装剂的液滴间通过。总体而言，这些功能性、响应性乳液提供了一种策略，可以向软材料结构赋予按需化学反应性，从而受益于系统的界面化学。
• POLYMER COMPOSITIONS CONTAINING GRAFTED POLYMERIC NETWORKS AND PROCESSES FOR THEIR PREPARATION AND USE
  申请人：Johnson & Johnson Vision Care, Inc.

  公开号：US20180037690A1

  公开（公告）日：2018-02-08

  Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator, (c) combining the crosslinked substrate network with a second reactive composition containing one or more ethylenically unsaturated compounds; and (d) activating the covalently bound activatable free radical initiator of the crosslinked substrate network such that the second reactive composition polymerizes therein with the crosslinked substrate network to form a grafted polymeric network and a byproduct polymer. Also provided are precursors to the polymer compositions, processes for preparation of the polymer compositions, and methods of using the polymer compositions, for instance in medical devices.

  提供的是由包括以下步骤的过程制备的聚合物组合物：(a)提供含有：(i)能够在第一激活时形成两个或更多自由基团的聚合引发剂，其中至少一个可以通过后续激活进一步激活；(ii)一个或多个乙烯基不饱和化合物；和(iii)交联剂的第一反应组合物；(b)将第一反应组合物暴露于第一激活步骤，使第一反应组合物在其中聚合形成含有共价结合的可激活自由基引发剂的交联基底网络；(c)将交联基底网络与含有一个或多个乙烯基不饱和化合物的第二反应组合物结合；和(d)激活交联基底网络的共价结合的可激活自由基引发剂，使第二反应组合物在其中与交联基底网络聚合形成嵌接聚合物网络和副产物聚合物。还提供了聚合物组合物的前体、制备聚合物组合物的过程以及使用聚合物组合物的方法，例如在医疗器械中的应用。
• HYDROXYPHENYL PHENANTHROLINES AS POLYMERIZABLE BLOCKERS OF HIGH ENERGY LIGHT
  申请人：Johnson & Johnson Vision Care, Inc.

  公开号：US20190002459A1

  公开（公告）日：2019-01-03

  Described are high energy light blocking compounds and ophthalmic devices containing the compounds. In particular, described are hydroxyphenyl phenanthroline structures with polymerizable functionality that block high energy light and are visibly transparent. The hydroxyphenyl phenanthroline structures can be incorporated into ophthalmic devices, such as hydrogel contact lenses, to protect eyes from high energy light radiation.

  描述了高能量光阻挡化合物和含有这些化合物的眼科器械。具体来说，描述了含有可聚合功能的羟基苯基菲啰啉结构，这些结构可以阻挡高能量光并且具有可见透明性。这些羟基苯基菲啰啉结构可以被应用到眼科器械中，比如水凝胶隐形眼镜，以保护眼睛免受高能量光辐射的伤害。
• HYDROXYPHENYL NAPHTHOTRIAZOLES AS POLYMERIZABLE BLOCKERS OF HIGH ENERGY LIGHT
  申请人：Johnson & Johnson Vision Care, Inc.

  公开号：US20190002415A1

  公开（公告）日：2019-01-03

  Described are high energy light blocking compounds and ophthalmic devices containing the compounds. In particular, described are hydroxyphenyl naphthotriazole structures with polymerizable functionality that block high energy light and are visibly transparent. The hydroxyphenyl naphthotriazole structures can be incorporated into ophthalmic devices, such as hydrogel contact lenses, to protect eyes from high energy light radiation.

  描述了高能量光阻挡化合物和含有这些化合物的眼科器械。具体描述了具有可聚合功能的羟基苯基萘三唑结构，该结构可以阻挡高能量光并且具有可见透明性。这些羟基苯基萘三唑结构可以被应用到眼科器械中，比如水凝胶隐形眼镜，以保护眼睛免受高能量光辐射的伤害。