2-甲基-5-(2-甲基-2-丙基)-1,3-苯并二氧戊环 | 85896-58-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并间二氧杂环戊烯类
• 中文名称: 2-甲基-5-(2-甲基-2-丙基)-1,3-苯并二氧戊环
• 英文名称: 2-Methyl-5-tert-butyl-1,3-benzodioxole
• 英文别名: 5-tert-butyl-2-methyl-1,3-benzodioxole
• CAS: 85896-58-8
• 化学式: C₁₂H₁₆O₂
• 分子量: 192.25
• InChiKey: QOAMCMUZZWSALB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Monoacylglycerol Lipase Modulators
  申请人：Janssen Pharmaceutica NV

  公开号：US20220332713A1

  公开（公告）日：2022-10-20

  Fused compounds of Formula (I) and Formula (II), pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with MGL modulation, such as those associated with pain, psychiatric disorders, neurological disorders (including, but not limited to major depressive disorder, treatment resistant depression, anxious depression, bipolar disorder), cancers and eye conditions. Wherein R 1 , R 2 , R 2a , R 3 , R 3a , R 4 , and R 4a are defined herein.
• US7285566B2
  申请人：——

  公开号：US7285566B2

  公开（公告）日：2007-10-23