2-pentoxy-5-carboxybenzaldehyde | 136084-61-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-pentoxy-5-carboxybenzaldehyde
• 英文别名: 3-Formyl-4-pentoxybenzoic acid
• CAS: 136084-61-2
• 化学式: C₁₃H₁₆O₄
• 分子量: 236.268
• InChiKey: SUOXXPUHQOKNSG-UHFFFAOYSA-N

物化性质

• 沸点：
  398.7±27.0 °C(Predicted)
• 密度：
  1.160±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1-碘戊烷 、 3-甲酰基-4-羟基苯甲酸 在 sodium hydroxide 作用下， 以 乙醇 为溶剂， 反应 4.0h， 以16%的产率得到2-pentoxy-5-carboxybenzaldehyde
  参考文献：
  名称：

  Piscopo; Diurno; Mazzoni, Il Farmaco, 1991, vol. 46, # 5, p. 669 - 676

  摘要：

  DOI：

文献信息

• Compositions containing aromatic aldehydes and their use in treatments
  申请人：——

  公开号：US20030124157A1

  公开（公告）日：2003-07-03

  Disclosed are pharmaceutical and cosmetic compositions containing aromatic aldehyde compounds. Some of the disclosed compositions are useful as topical therapeutics for treating inflammatory dermatologic conditions. Some of the compositions are useful in transdermal and other systemic dose forms for treating other inflammatory conditions in mammals.

  揭示了含有芳香醛类化合物的药用和化妆品组合物。其中一些组合物可用作治疗炎症性皮肤病的局部治疗药物。其中一些组合物可用于治疗哺乳动物体内其他炎症性疾病的经皮和其他系统剂型。
• COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENT
  申请人：Engles R. Charles

  公开号：US20080004354A1

  公开（公告）日：2008-01-03

  Disclosed are pharmaceutical and cosmetic compositions containing aromatic aldehyde compounds. Some of the disclosed compositions are useful as topical therapeutics for treating inflammatory dermatologic conditions. Some of the compositions are useful in transdermal and other systemic dose forms for treating other inflammatory conditions in mammals.
• Compositions Containing Aromatic Aldehydes and Their Use in Treatments
  申请人：Engles Charles R.

  公开号：US20120157546A1

  公开（公告）日：2012-06-21

  Disclosed are pharmaceutical and cosmetic compositions containing aromatic aldehyde compounds. Some of the disclosed compositions are useful as topical therapeutics for treating inflammatory dermatologic conditions. Some of the compositions are useful in transdermal and other systemic dose forms for treating other inflammatory conditions in mammals.
• COMPOSITIONS CONTAINING AROMATIC ALDEHYDES AND THEIR USE IN TREATMENTS
  申请人：ENGLES Charles R.

  公开号：US20130035359A1

  公开（公告）日：2013-02-07

  Disclosed are pharmaceutical and cosmetic compositions containing aromatic aldehyde compounds. Some of the disclosed compositions are useful as topical therapeutics for treating inflammatory dermatologic conditions. Some of the compositions are useful in transdermal and other systemic dose forms for treating other inflammatory conditions in mammals.
• US8246969B2
  申请人：——

  公开号：US8246969B2

  公开（公告）日：2012-08-21