1-amino-hexadecan-2-ol | 14627-64-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-amino-hexadecan-2-ol
• 英文别名: 2-Hydroxy-hexadecylamin；1-Aminohexadecan-2-OL
• CAS: 14627-64-6
• 化学式: C₁₆H₃₅NO
• 分子量: 257.46
• InChiKey: QJARJRBYFJRFGX-UHFFFAOYSA-N

物化性质

• 沸点：
  380.8±15.0 °C(Predicted)
• 密度：
  0.875±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  18
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  46.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-amino-hexadecan-2-ol 、 碳酸二乙酯 在 sodium methylate 作用下， 生成 5-n-Tetradecyl-2-oxazolidon
  参考文献：
  名称：

  Chemistry of epoxy compounds. XXI. Reaction of potassium cyanate with epoxides

  摘要：

  DOI：

  10.1021/jo01265a076
• 作为产物：
  描述：

  十六碳烯 在 氨 、 碳酸氢钠 、 间氯过氧苯甲酸 作用下， 以 二氯甲烷 为溶剂， 生成 1-amino-hexadecan-2-ol
  参考文献：
  名称：

  Long-Chain Aminoalcohol and Diamine Derivatives Induce Apoptosis through a Caspase-3 Dependent Pathway

  摘要：

  A number of long chain diamines and aminoalcohols and several of their alkyl, acyl and carbamoyl derivatives, have been synthesized and evaluated for their apoptotic activities using the Jurkat cell line. Apoptosis was measured by flow cytometry and the best results were found for the aminoalcohols displaying either a free alcohol or an amine with at least, one free hydrogen atom. The apoptotic pathway was mediated by a disruption of the mitochondria transmembrane potential and caspase-3 activation, inducing DNA fragmentation at the phase G(1)/S of the cell cycle. (C) 2002 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(02)00476-6

文献信息

• Pentaerythritol-spiro-bis-phosphite compositions having improved hydrolytic stability
  申请人：Argus Chemical Corporation

  公开号：EP0143464A2

  公开（公告）日：1985-06-05

  Pentaerythritol-spiro-bis-phosphite compositions are provided having an improved hydrolytic stability, comprising (1) a pentaerythritol-spiro-bis-phosphite of the formula: wherein: R, and R2 are selected from the group consisting of alkyl and alkylaryl groups having at least fourteen carbon atoms up to about thirty-six carbon atoms; and (2) a long-chain aliphatic amine in an amount to improve the hydrolytic stability of the phosphite and having the formula: wherein: R3, R4, and R5 are selected from the group consisting of hydrogen; aliphatic (including alkyl and alkenyl) groups having from one to about thirty-six carbon atoms; and hydroxyalkyl having from two to about six carbon atoms; one of R3, R4 and R5 is an aliphatic group having at least fourteen carbon atoms, and the remaining of R3, R4 and R5 are selected from hydrogen, alkyl having from one to four carbon atoms and hydroxyalkyl; and preferably at least one of R3, R4 and R5 is hydroxyalkyl.

  提供了具有更好水解稳定性的季戊四醇螺二亚磷酸组合物，其中包括 (1) 式中的季戊四醇螺二亚磷酸： 其中 R和R2选自由至少具有十四个碳原子至约三十六个碳原子的烷基和烷芳基所组成的组；和 (2) 长链脂肪族胺，其用量可提高亚磷酸酯的水解稳定性，其式为 其中 R3、R4 和 R5 选自由氢、具有一至约三十六个碳原子的脂肪族（包括烷基和烯基）基团和具有二至约六个碳原子的羟烷基组成的组；R3、R4 和 R5 中的一个是具有至少十四个碳原子的脂肪族基团，R3、R4 和 R5 中的其余部分选自由氢、具有一至四个碳原子的烷基和羟烷基；优选 R3、R4 和 R5 中的至少一个是羟烷基。
• Process for preparation of diacetal compounds
  申请人：NEW JAPAN CHEMICAL CO.,LTD.

  公开号：EP0421329A2

  公开（公告）日：1991-04-10

  Disclosed is a process for preparing a diacetal compound of the formula (I) such as a dibenzylidene sorbitol, comprising the steps of(i) condensing an aldehyde compound and a polyhydric alcohol in the presence of an acid catalyst and when required a lower alcohol in a hydrophobic organic solvent to give a reaction mixture containing a diacetal compound, (ii) neutralizing the reaction mixture, (iii) washing the mixture with water, (iv) removing the solvent from the mixture thus washed, and (v) drying the residual mass; the process being characterized in that an amine such as, for example, di(C₁₀-C₂₆ alkyl or alkenyl)amine substituted on the nitrogen atom with a C₁-C₄ alkyl group or with a group of the formula (̵C₂H₄O)qH wherein q is an integer of 1 to 4, or a (C₁₄-C₂₂ alkyl or alkenyl)amine substituted on the nitrogen atom with one or two groups of the formula (̵C₂H₄O)qH wherein q is 1 to 4, is added during the period from the formation of the reaction mixture to the completion of the drying step.

  本发明公开了一种制备式(I)的二缩醛化合物（如二亚苄基山梨醇）的工艺，包括以下 步骤：(i)在酸催化剂存在下，必要时在低级醇存在下，在疏水性有机溶剂中缩合醛化合物 和多元醇，得到含有二缩醛化合物的反应混合物；(ii)中和反应混合物；(iii)用水洗涤混合物； (iv)从这样洗涤的混合物中除去溶剂；(v)干燥残留物；该工艺的特征在于胺，例如在氮原子上被 C₁-C₄ 烷基或式 (̵C₂H₄O)qH 的基团取代的二(C₁₀-C₂₆ 烷基或烯基)胺，其中 q 为 1 至 4 的整数、或(C₁₄-C₂₂烷基或烯基)胺，在氮原子上被一个或两个式(̵C₂H₄O)qH（其中 q 为 1 至 4）的基团取代，在反应混合物形成至干燥步骤完成期间加入。
• ANTISTATIC NON-CROSSLINKED FOAMED POLYETHYLENE RESIN PARTICLES AND MOLDED NON-CROSSLINKED FOAMED POLYETHYLENE RESIN BODY
  申请人：Kaneka Corporation

  公开号：EP2733164A1

  公开（公告）日：2014-05-21

  Provided are non-crosslinked foamed polyethylene resin particles that have a bulk density BD of 10 g/L or more and 100 g/L or less and are obtained by foaming polyethylene resin particles containing an antistatic agent in an amount of 0.1 part by weight or more and 3 parts by weight or less with respect to 100 parts by weight of a polyethylene resin and having a density of 0.920 g/cm3 or more and less than 0.940 g/cm3, and the non-crosslinked foamed polyethylene resin particles have a shrinkage ratio of 3% or more and 30% or less determined in accordance with Formula (1). The non-crosslinked foamed polyethylene resin particles can simply afford an antistatic molded non-crosslinked foamed polyethylene resin body that has a small shrinkage ratio with respect to mold dimension, is deformed in a small degree, and has good surface stretch. Shrinkage ratio = (BD-VBD) x 100/VBD (1) In the formula, BD is a bulk density of the non-crosslinked foamed polyethylene resin particles at 23°C and 0.1 MPa (under standard atmospheric pressure), and VBD is a bulk density of the non-crosslinked foamed polyethylene resin particles at 23°C under a reduced pressure of 0.002 MPa or less.

  所提供的非交联发泡聚乙烯树脂颗粒的体积密度 BD 为 10 g/L 或以上、100 g/L 或以下，是通过发泡含有抗静电剂的聚乙烯树脂颗粒获得的，抗静电剂的用量为 0.该非交联发泡聚乙烯树脂颗粒的收缩率为3%或以上，30%或以下，根据式(1)测定，其密度为0.920克/立方厘米或以上，0.940克/立方厘米以下。非交联发泡聚乙烯树脂颗粒可以简单地提供抗静电模塑非交联发泡聚乙烯树脂体，该体相对于模具尺寸的收缩率小，变形程度小，表面伸展性好。收缩率＝（BD-VBD）×100/VBD (1) 式中，BD 是非交联发泡聚乙烯树脂颗粒在 23℃和 0.1 兆帕（标准大气压下）时的体积密度，VBD 是非交联发泡聚乙烯树脂颗粒在 23℃、减压 0.002 兆帕或以下时的体积密度。
• LUBRICATING OIL COMPOSITION, AND SLIDING MECHANISM USING LUBRICATING OIL COMPOSITION
  申请人：Idemitsu Kosan Co., Ltd

  公开号：EP2826845A1

  公开（公告）日：2015-01-21

  Disclosed is a lubricating oil composition for low-friction sliding materials, which is used in a sliding mechanism where a DLC film containing hydrogen in an amount of from 5 atom% to 50 atom% is formed on at least one sliding surface. The lubricating oil composition contains, in the lubricant base oil therein and based on the total amount of the composition, (A) an organic zinc dithiophosphate in an amount of from 0.005% by mass to 0.12% by mass in terms of the phosphorus concentration therein, (B) an amine-based friction-reducing agent in an amount of from 0.05% by mass to 5.0% by mass, and (C) an alkaline earth metal salicylate-based detergent and/or an alkaline earth metal sulfonate-based detergent in an amount of from 0.05% by mass to 0.5% by mass in terms of the alkaline earth metal concentration therein, wherein the component (A) contains, based on the total amount of the composition, a zinc primary dialkyldithiophosphate in an amount of from 0.005% by mass to 0.05% by mass in terms of the phosphorus concentration therein.

  本发明公开了一种用于低摩擦滑动材料的润滑油组合物，该组合物用于在至少一个滑动表面上形成含氢量为 5 原子％至 50 原子％的 DLC 膜的滑动机构中。该润滑油组合物在其中的润滑油基础油中，根据组合物的总量，含有 (A) 有机二硫代磷酸锌，以其中的磷浓度计，含量为 0.005% （质量百分比）至 0.12% （质量百分比）；(B) 基于胺的减摩剂，含量为 0.05% （质量百分比）至 5.(C) 碱土金属水杨酸酯类洗涤剂和/或碱土金属磺酸盐类洗涤剂，以其中碱土金属的浓度计，其用量为 0.05% (质量) 至 0.5% (质量)，其中组分 (A) 含有以组合物总量计，以其中磷的浓度计，其用量为 0.005% (质量) 至 0.05% (质量)的伯基二烷基二硫代磷酸锌。
• LUBRICANT OIL COMPOSITION
  申请人：Idemitsu Kosan Co., Ltd

  公开号：EP2937409A1

  公开（公告）日：2015-10-28

  A lubricant oil composition of the present invention that is prepared by blending a boron-containing compound therein, the boron-containing compound having a ratio of an integrated value of peaks in the 5 to 25 ppm chemical shift to an integrated value of peaks in the -10 ppm to 25 ppm chemical shift, as determined by 11B-NMR measurement in deuterochloroform using BF3·OEt2 as an external standard (0 ppm), of 0.5 or higher and 1.0 or lower.

  本发明的一种润滑油组合物，是通过在其中掺入一种含硼化合物而制备的，该含硼化合物的 5 至 25 ppm 化学位移峰的综合值与-10 ppm 至 25 ppm 化学位移峰的综合值之比（以 BF3-OEt2 为外标（0 ppm），在脱氯甲烷中进行 11B-NMR 测量而得）为 0.5 或更高，1.0 或更低；该含硼化合物的-10 ppm 至 25 ppm 化学位移峰的综合值与-10 ppm 至 25 ppm 化学位移峰的综合值之比（以 BF3-OEt2 为外标（0 ppm），在脱氯甲烷中进行 11B-NMR 测量而得）为 0.5 或更高，1.0 或更低。