2-甲基异喹啉-1(2H)-硫酮 | 14945-74-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 中文名称: 2-甲基异喹啉-1(2H)-硫酮
• 英文名称: 2-methyl-1(2H)-thioisoquinolone
• 英文别名: 2-Methyl-1(2H)-thioisochinolon；2-Methylisoquinoline-1-thione
• CAS: 14945-74-5
• 化学式: C₁₀H₉NS
• mdl: MFCD04037471
• 分子量: 175.254
• InChiKey: IEXYLQOPBXUDSK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  35.3
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-甲基异喹啉-1(2H)-硫酮 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 反应 18.67h， 生成 1,2-dihydro-1-[bis(methoxycarbonyl)methylene]-2-methylisoquinoline
  参考文献：
  名称：

  1-烷硫基异喹啉鎓盐与活性亚甲基化合物的反应。

  摘要：

  由2-烷基-1（2H）-异喹诺酮经2-烷基1（2H）-硫代异喹诺酮分两步制备2-烷基-1-烷基硫代异喹啉鎓盐。在温和的条件下，在氢化钠存在下2-烷基-1-烷基硫代异喹啉鎓盐与活性亚甲基化合物的反应以良好的收率得到了2-烷基-1-（取代的亚甲基）异喹啉。吡咯并[2,1-a]异喹啉是通过使用乙酸酐对2-苄基-1-（取代的亚甲基）异喹啉进行环化而合成的。

  DOI：

  10.1248/cpb.50.225
• 作为产物：
  描述：

  2-甲基异喹啉-1(2H)-酮 在 吡啶 、 phosphorous (V) sulfide 作用下， 生成 2-甲基异喹啉-1(2H)-硫酮
  参考文献：
  名称：

  777.抗结核化合物。部分X.衍生自季铵化合物的一些反应NN二取代的硫代酰胺

  摘要：

  DOI：

  10.1039/jr9520004067

文献信息

• POLYMERIZABLE COMPOUND AND OPTICAL ISOMER
  申请人：DIC Corporation

  公开号：US20180022716A1

  公开（公告）日：2018-01-25

  The present invention provides a polymerizable compound having high storage stability without causing crystal precipitation when added to a polymerizable composition. The present invention also provides a polymerizable composition containing the compound. When the filmy polymer produced through polymerization of the polymerizable composition is irradiated with UV light, it hardly discolors or peels from substrate. Further, the present invention provides a polymer produced through polymerization of the polymerizable composition and an optically anisotropic body using the polymer.

  本发明提供了一种聚合物化合物，具有高储存稳定性，添加到聚合物化合物时不会导致结晶沉淀。本发明还提供了含有该化合物的聚合物化合物。当通过聚合物化合物的聚合产生薄膜状聚合物时，若用紫外光照射，它几乎不会变色或脱落。此外，本发明提供了通过聚合物化合物的聚合产生的聚合物，以及使用该聚合物的光学各向异性体。
• [EN] POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY<br/>[FR] COMPOSÉ POLYMÉRISABLE ET CORPS OPTIQUEMENT ANISOTROPE
  申请人：DAINIPPON INK & CHEMICALS

  公开号：WO2017079867A1

  公开（公告）日：2017-05-18

  There is provided a polymerizable composition, by which discoloration or alignment defects are less likely to occur when a filmy polymer, which is obtained by adding a polymerizable compound to the polymerizable composition and polymerizing this composition, is irradiated with ultraviolet light. There are also provided a polymer obtained by polymerizing the polymerizable composition, and an optically anisotropic body using the polymer. The present invention provides a polymerizable low-wavelength dispersive or polymerizable reverse-wavelength dispersive compound having a partial structure represented by Formula (Z-0). Further, the present invention provides a composition containing the compound; a polymer obtained by polymerizing the composition; and an optically anisotropic body obtained by using the polymer.

  提供一种可聚合的组合物，通过该组合物得到的薄膜聚合物在紫外光照射时，不太容易发生变色或排列缺陷。还提供了通过聚合该聚合物组合物得到的聚合物，以及使用该聚合物的光学各向异性体。本发明提供了一种具有由式（Z-0）表示的部分结构的可聚合低波长色散或可聚合反波长色散化合物。此外，本发明提供了一种含有该化合物的组合物；通过聚合该组合物得到的聚合物；以及通过使用该聚合物得到的光学各向异性体。
• COMPOSITION INCLUDING COMPOUND HAVING MESOGENIC GROUP, POLYMER AND OPTICALLY ANISOTROPIC BODY OBTAINED BY POLYMERIZING POLYMERIZABLE COMPOSITION, AND PHASE DIFFERENCE FILM
  申请人：DIC Corporation

  公开号：EP3346304A1

  公开（公告）日：2018-07-11

  A polymerizable composition of the present invention has favorable solubility, and an optically anisotropic body using the polymerizable composition is unlikely to discolor and is excellent in heat resistance and light resistance. The problem to be solved by the present invention is to provide a polymer obtained by polymerizing the polymerizable composition and an optically anisotropic body using the polymer. The present invention relates to a polymerizable composition which includes a compound having at least one mesogenic group and satisfying an expression represented by Expression (1), and which satisfies an expression represented by Expression (2) . 0.5≤YI/Δn≤500

  本发明的可聚合组合物具有良好的溶解性，使用该可聚合组合物的光学各向异性体不易褪色，且具有优异的耐热性和耐光性。本发明要解决的问题是提供一种通过聚合该可聚合组合物而得到的聚合物和一种使用该聚合物的光学各向异性体。本发明涉及一种可聚合组合物，它包括具有至少一个介原基并满足表达式（1）所表示的表达式的化合物，并且满足表达式（2）所表示的表达式。0.5≤YI/Δn≤500
• Composition including compound having mesogenic group, polymer and optically anisotropic body obtained by polymerizing polymerizable composition, and phase difference film
  申请人：DIC Corporation

  公开号：US10649124B2

  公开（公告）日：2020-05-12

  A polymerizable composition of the present invention has favorable solubility, and an optically anisotropic body using the polymerizable composition is unlikely to discolor and is excellent in heat resistance and light resistance. The problem to be solved by the present invention is to provide a polymer obtained by polymerizing the polymerizable composition and an optically anisotropic body using the polymer. The present invention relates to a polymerizable composition which includes a compound having at least one mesogenic group and satisfying an expression represented by Expression (1), and which satisfies an expression represented by Expression (2). 0.5≤YI/Δn≤500  Expression (2)

  本发明的可聚合组合物具有良好的溶解性，使用该可聚合组合物的光学各向异性体不易褪色，且具有优异的耐热性和耐光性。本发明要解决的问题是提供一种通过聚合该可聚合组合物而得到的聚合物和一种使用该聚合物的光学各向异性体。本发明涉及一种可聚合组合物，该组合物包括一种具有至少一个介原基并满足表达式（1）所表示的表达式的化合物，以及满足表达式（2）所表示的表达式的可聚合组合物。 0.5≤YI/Δn≤500 表达式 (2)
• Polymerizable compound and optically anisotropic body
  申请人：DIC CORPORATION

  公开号：US10919870B2

  公开（公告）日：2021-02-16

  There is provided a polymerizable composition, by which discoloration or alignment defects are less likely to occur when a filmy polymer, which is obtained by adding a polymerizable compound to the polymerizable composition and polymerizing this composition, is irradiated with ultraviolet light. There are also provided a polymer obtained by polymerizing the polymerizable composition, and an optically anisotropic body using the polymer. The present invention provides a polymerizable low-wavelength dispersive or polymerizable reverse-wavelength dispersive compound having a partial structure represented by Formula (Z-0). Further, the present invention provides a composition containing the compound; a polymer obtained by polymerizing the composition; and an optically anisotropic body obtained by using the polymer.

  本发明提供了一种可聚合组合物，通过在该可聚合组合物中添加可聚合化合物并使其聚合而得到的薄膜状聚合物在紫外线照射下不易出现变色或排列缺陷。本发明还提供了一种通过聚合该可聚合组合物而获得的聚合物，以及使用该聚合物的光学各向异性体。本发明提供了一种可聚合的低波长分散性或可聚合的反向波长分散性化合物，其部分结构由式（Z-0）表示。此外，本发明还提供了一种含有该化合物的组合物；一种通过聚合该组合物而获得的聚合物；以及一种通过使用该聚合物而获得的光学各向异性体。