3-(4-([2,2';6',2'']terpyridin-4'-yl)phenoxy)propane-1-sulfonic acid | 1222558-91-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 3-(4-([2,2';6',2'']terpyridin-4'-yl)phenoxy)propane-1-sulfonic acid
• 英文别名: 3-(4-(terpyridin-4'-yl)phenoxy)propane-1-sulfonic acid；3-[4-(2,6-Dipyridin-2-ylpyridin-4-yl)phenoxy]propane-1-sulfonic acid；3-[4-(2,6-dipyridin-2-ylpyridin-4-yl)phenoxy]propane-1-sulfonic acid
• CAS: 1222558-91-9
• 化学式: C₂₄H₂₁N₃O₄S
• 分子量: 447.514
• InChiKey: KYKVBNRYOYCNAE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  32
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  111
• 氢给体数：
  1
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  2-乙酰基吡啶 、 3-(4-甲酰基苯氧基)丙烷-1-磺酸 在 乙酰胺 、 ammonium acetate 、 sodium hydroxide 作用下， 以 水 为溶剂， 反应 2.0h， 以82%的产率得到3-(4-([2,2';6',2'']terpyridin-4'-yl)phenoxy)propane-1-sulfonic acid
  参考文献：
  名称：

  Reusable Polymer-Supported Terpyridine Copper Complex for [3+2] Huisgen Cycloaddition in Water

  摘要：

  A polymer-supported terpyridine copper(I) complex was prepared and found to promote the Huisgen [3+2] cycloaddition reaction between azides and alkynes in water to give the corresponding triazoles with up to 87% isolated yield. This catalyst was recovered and reused several times without any loss in catalytic activity.

  DOI：

  10.3987/com-09-11872

文献信息

• Suzuki–Miyaura Cross-Coupling Reaction in Water with Polymer-Supported Terpyridine Palladium Complex Under Aerobic Conditions
  作者：Toshimasa Suzuka、Takuya Nagamine、Kazuhito Ogihara、Matsutake Higa

  DOI：10.1007/s10562-010-0422-0

  日期：2010.11

  A polymer-supported terpyridine Pd(II) complex was prepared and found to promote the Suzuki-Miyaura coupling reaction in water. Thus, terpyridine ligand was prepared from p-hydroxybenzaldehyde, propane sultone, and 2-acetylpyridine according to the reported procedures. Immobilization of terpyridine ligand onto a polystyrene-poly(ethylene glycol) (PS-PEG) resin through ionic bonds to sulfonate group took place and the complexation of PS-PEG-terpyridine ligand with Pd(II) underwent to give PS-PEG-terpyridine-Pd(II) complex. This polymeric catalyst showed high catalytic activity and high reusability for the Suzuki-Miyaura coupling reaction.
• Reusable Polymer-Supported Terpyridine Copper Complex for [3+2] Huisgen Cycloaddition in Water
  作者：Toshimasa Suzuka、Kazumasa Ooshiro、Ken’yu Kina

  DOI：10.3987/com-09-11872

  日期：——

  A polymer-supported terpyridine copper(I) complex was prepared and found to promote the Huisgen [3+2] cycloaddition reaction between azides and alkynes in water to give the corresponding triazoles with up to 87% isolated yield. This catalyst was recovered and reused several times without any loss in catalytic activity.