nonanophenone oxime | 95412-08-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: nonanophenone oxime
• 英文别名: N-(1-phenylnonylidene)hydroxylamine
• CAS: 95412-08-1
• 化学式: C₁₅H₂₃NO
• 分子量: 233.354
• InChiKey: OZOKAVMHGSEHME-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  17
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  32.6
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  nonanophenone oxime 、 乙炔 在 potassium hydroxide 作用下， 以 二甲基亚砜 为溶剂， 反应 7.0h， 以63%的产率得到3-n-heptyl-2-phenyl-1-vinylpyrrole
  参考文献：
  名称：

  3-Alkyl-2-phenyl-1-vinylpyrroles from ketoximes and acetylene: an improved synthesis by the Trofimov reaction

  摘要：

  A one-pot synthesis of 3-alkyl-2-phenyl-1-vinylpyrroles, giving high yields at atmospheric pressure, was developed on the basis of reacting alkyl phenyl ketoximes with acetylene in a KOH-DMSO system (the Trofimov reaction).

  DOI：

  10.1007/s10593-013-1184-6

文献信息

• One-Pot Preparation of 2-Arylbenzofurans from Oximes with Diaryliodonium Triflate
  作者：Hideo Togo、Kotaro Miyagi、Katsuhiko Moriyama

  DOI：10.3987/com-14-13071

  日期：——

  A variety of 2-arylbenzofurans were obtained in good yields by the O-arylation of oximes with diaryliodonium triflates, followed by the treatment with HCl in dioxane under warming conditions through the [3,3]-sigmatropic reaction. The present reaction is one-pot transition metal-free method for the preparation of various 2-arylbenzofurans from oximes, which are easily available from the reaction of alkyl aryl ketones with hydroxylamine
• 3-Alkyl-2-phenyl-1-vinylpyrroles from ketoximes and acetylene: an improved synthesis by the Trofimov reaction
  作者：O. V. Petrova、L. N. Sobenina、A. I. Mikhaleva

  DOI：10.1007/s10593-013-1184-6

  日期：2013.2

  A one-pot synthesis of 3-alkyl-2-phenyl-1-vinylpyrroles, giving high yields at atmospheric pressure, was developed on the basis of reacting alkyl phenyl ketoximes with acetylene in a KOH-DMSO system (the Trofimov reaction).