A new regio- and stereoselective synthesis of β-enamino ketones with 3-ethoxycyclobutanones and substituted amines
作者:Pengfei Liu、Gang Shan、Shi Chen、Yu Rao
DOI:10.1016/j.tetlet.2011.12.040
日期:2012.2
A new method toward regio- and stereoselective synthesis of β-enamino ketones is described. Through Lewis acid-catalyzed reactions between 3-ethoxycyclobutanones and substituted amines, a variety of cis and trans β-enamino ketone derivatives were prepared with complete regio- and stereoselectivity at room temperature.
描述了一种向区域和立体选择性合成β-烯氨基酮的新方法。通过路易斯酸在3-乙氧基环丁酮和取代的胺之间的催化反应,在室温下制备了具有完全区域和立体选择性的各种顺式和反式β-烯胺酮衍生物。