3-methylamino-3-phenyl-1,2-propanediol | 873396-25-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 3-methylamino-3-phenyl-1,2-propanediol
• 英文别名: 3-methylamino-3-phenyl-propane-1,2-diol；3-Methylamino-3-phenyl-propan-1,2-diol；3-(methylamino)-3-phenylpropane-1,2-diol
• CAS: 873396-25-9
• 化学式: C₁₀H₁₅NO₂
• 分子量: 181.235
• InChiKey: LNHCVGWTRFGMJB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  13.0
• 可旋转键数：
  4.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  52.49
• 氢给体数：
  3.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  3-methylamino-3-phenyl-1,2-propanediol 在 咪唑 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 27.0h， 生成 cis-5-(tert-butyldimethylsilyloxymethyl)-3-methyl-4-phenyl-1,3-oxazolidin-2-one
  参考文献：
  名称：

  双光气与光气在与（2,3-抗）-3-氨基-1,2-二醇反应中的反应性差异

  摘要：

  在（2,3-抗）-3-氨基-1,2-二醇与双光气和光气的反应以及它们转化为1,3-恶唑烷-2-酮的反应中，已发现反应的立体化学存在一些差异。这两种试剂。与光气的反应提供了预期的顺式-恶唑烷酮，并且在相同的反应条件下与双光气的反应中，还获得了反式-恶唑烷酮。

  DOI：

  10.1016/j.tet.2006.04.033
• 作为产物：
  描述：

  乙酸肉桂酯 在 乙醚 、 碘 、 mercury(II) oxide 作用下， 生成 3-methylamino-3-phenyl-1,2-propanediol
  参考文献：
  名称：

  Electrohydrodynamically Enhanced Convective Boiling of Alternative Refrigerants: Fundamental Understanding and Applicability

  摘要：

  Electrohydrodynamically (EHD) enhanced convective boiling, based on the extraction phenomenon, is experimentally investigated. The working fluids are R-134a and R404A refrigerants. Both smooth and enhanced tubes are investigated in a horizontal configuration. The heat transfer enhancement and suppression with the corresponding pressure-drop data are presented. The ratio of EHD power consumption relative to the heat transferred was less than 1.5% for the data presented A theoretical analysis is presented to determine the contributing terms of the EHD power consumption, and it was determined that the electric conduction mechanism was the primary contributing factor to current flow. The transient application of EHD, in the case that resulted in the suppression of the heat transfer under steady-state conditions, provided transient enhancements for convective boiling of R-404A in a horizontal smooth tube. Additional, applicability of the EHD extraction phenomenon to convective boiling is discussed.

  DOI：

  10.1080/10789669.2002.10391294

文献信息

• Über die Umsetzung von Epoxyden mit Aminen
  作者：K. Bodendorf、Karl Dettke

  DOI：10.1002/ardp.19582910205

  日期：——
• Operative treatment of avulsion fractures of the anterior superior iliac spine according to the tension band principle
  作者：Miloš Kosanović、Drago Brilej、Radko Komadina、Božidar Buhanec、Iztok Pilih、Miodrag Vlaović

  DOI：10.1007/s00402-002-0396-5

  日期：2002.11

  Background: Avulsion fractures of the anterior superior iliac spine are uncommon injuries. Most of them occur in adolescent athletes. Traditionally, they have been treated conservatively. We describe operative treatment of avulsion fractures that might shorten the period of rehabilitation. Methods and results: Six patients with avulsion fractures of the anterior superior iliac spine were treated operatively by open reduction and osteosynthesis with two Kirschner wires and a wire loop. After 6 weeks, all of them had resumed their sports activities. No complications were recorded. Conclusions: Operative treatment of anterior superior iliac spine avulsions may reduce the time to full recovery. It should be considered for athletes requiring a short period of rehabilitation.