2-羟基-4-甲氧基二苯甲酮-5-磺酸钠 | 6628-37-1

• 物质功能分类: 催化剂及助剂 - 紫外线吸收剂
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2-羟基-4-甲氧基二苯甲酮-5-磺酸钠
• 中文别名: 2-二羟基-4-甲氧基二苯甲酮-5-磺酸钠；二苯酮-5
• 英文名称: 5-Benzoyl-4-hydroxy-2-methoxybenzenesulfonic acid, sodium salt
• CAS: 6628-37-1
• 化学式: C14H12NaO6S
• 分子量: 331.3
• InChiKey: YCSKILQQVIHGJI-UHFFFAOYSA-N

物化性质

• 溶解度：
  DMSO（少许）、甲醇（少许）、水（少许）
• LogP：
  0.888 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  109
• 氢给体数：
  2
• 氢受体数：
  6

安全信息

• 危险品标志：
  Xi
• 安全说明：
  S26,S36
• 危险类别码：
  R36/37/38

制备方法与用途

用途

2-羟基-4-甲氧基二苯甲酮-5-磺酸钠是一种酮类衍生物，也被称为二苯酮-5，可用作紫外线吸收剂。

防晒剂成分

紫外线吸收剂BP-5可用于防晒剂中，规定使用时的最大浓度不超过5%。

文献信息

• SKIN EXTERNAL PREPARATIONS AND COSMETICS
  申请人：Aoki Hirobumi

  公开号：US20100280111A1

  公开（公告）日：2010-11-04

  An object of the present invention is to provide skin external preparations and cosmetics which contain a branched acyl carnitine and have excellent formulation stability. A skin external preparation of the present invention includes a carnitine derivative represented by the following Formula (1) and/or a carnitine derivative salt represented by the following Formula (2), and an amphoteric surfactant. In Formula (1), R 1 and R 2 are each independently a C1-18 optionally branched, saturated or unsaturated aliphatic hydrocarbon group. In Formula (2), R 1 and R 2 are the same as in Formula (1), X − is a specific anion and Y + is a specific cation.

  本发明的一个目的是提供含有支链酰基肉碱并具有优异配方稳定性的皮肤外用制剂和化妆品。本发明的皮肤外用制剂包括以下式（1）所表示的肉碱衍生物和/或以下式（2）所表示的肉碱衍生物盐，以及一种两性表面活性剂。在式（1）中，R1和R2分别独立地是C1-18的可选支链、饱和或不饱和脂肪烃基。在式（2）中，R1和R2与式（1）中相同，X−是特定的阴离子，Y+是特定的阳离子。
• METHOD AND COMPOSITIONS FOR TREATING SKIN
  申请人：MAES DANIEL H.

  公开号：US20090220481A1

  公开（公告）日：2009-09-03

  A skin care composition comprising at least one keratinocyte CLOCK or PER1 gene activator and at least one DNA repair enzyme; a method for inhibiting damage to human keratinocytes due to environmental aggressors by applying a composition comprising at least one keratinocyte CLOCK or PER1 gene activator and at least one DNA repair enzyme; and a method for repairing DNA damage in human keratinocytes.

  一种皮肤护理组合物，包括至少一种角质细胞CLOCK或PER1基因激活剂和至少一种DNA修复酶；一种通过应用包含至少一种角质细胞CLOCK或PER1基因激活剂和至少一种DNA修复酶的组合物来抑制人类角质细胞受环境侵害的损伤的方法；以及一种修复人类角质细胞中DNA损伤的方法。
• Method And Compositions For Improving Selective Catabolysis And Viability In Cells Of Keratin Surfaces
  申请人：ELC Management LLC

  公开号：US20140193391A1

  公开（公告）日：2014-07-10

  A composition for treating keratin surfaces to stimulate selective catabolysis and improve cellular viability comprising at least one autophagy activator and at least one DNA repair enzyme, and a method for improving selective catabolysis and cellular viability by treating with the composition.

  一种用于处理角蛋白表面以刺激选择性分解并改善细胞生存能力的组合物，包括至少一种自噬激活剂和至少一种DNA修复酶，以及一种通过使用该组合物来改善选择性分解和细胞生存能力的方法。
• Cysteine derivatives
  申请人：AJINOMOTO CO., INC.

  公开号：US20020115723A1

  公开（公告）日：2002-08-22

  Objects of the present invention are to provide an oxidative stress inhibitor which is capable of suppressing the expression of a cytotoxic protein and the activation of a gene transcriptional regulatory factor taking part such expression of a cytotoxic protein and exhibits good feeling upon use and safety; to provide a method for preventing, retarding, alleviating or treating a skin change due to aging or an undesirable aesthetic skin change, both caused or promoted by an oxidative stress; and to provide a cosmetic composition or dermatologic preparation for external use comprising the oxidative stress inhibitor as an effective ingredient, and for those purposes are employed an oxidative stress inhibiting agent which comprises, as an effective ingredient, at least one selected from cysteine or cystine derivatives and the salts thereof.

  本发明的目的是提供一种能够抑制细胞毒蛋白表达和基因转录调节因子激活的氧化应激抑制剂，该抑制剂在使用时具有良好的感觉和安全性；提供一种预防、延缓、缓解或治疗由氧化应激引起或促进的皮肤老化或不良美容皮肤变化的方法；提供一种含有氧化应激抑制剂作为有效成分的用于外用的化妆品组合物或皮肤科制剂。为了实现这些目的，使用一种氧化应激抑制剂，其有效成分包括至少一种来自半胱氨酸或半胱氨酸衍生物及其盐的物质。
• [EN] A SKIN CARE AND COSMETIC PREPARATION CONTAINING AN INOSITOL DERIVATIVE<br/>[FR] UNE PRÉPARATION COSMÉTIQUE ET DERMATOLOGIQUE CONTENANT UN DÉRIVÉ INOSITOL
  申请人：SHOWA DENKO KK

  公开号：WO2005092285A1

  公开（公告）日：2005-10-06

  The present invention discloses a preparation to be applied externally to the skin which contains an inositol derivative in which an inositol and a saccharide are combined. The invention aims to provide an external skin preparation that can be spread over skin without causing a granular feeling and has excellent moisturising effects and of keeping the skin healthy.

  本发明公开了一种用于外部涂抹于皮肤的制剂，其中包含一种肌醇衍生物，该肌醇衍生物中结合了肌醇和一种糖类。该发明旨在提供一种外用皮肤制剂，可以在皮肤上涂抹而不会产生颗粒感，具有优秀的保湿效果，并保持皮肤健康。