KPF<sub>6</sub>-Mediated Esterification and Amidation of Carboxylic Acids
作者:Sonam、Vikki N. Shinde、Anil Kumar
DOI:10.1021/acs.joc.1c02611
日期:2022.3.4
been developed for the synthesis of esters and amides. A wide range of carboxylicacids and alcohols or amines worked well under the developed reaction conditions, thus providing good to excellent (61–98%) yields of the corresponding esters and amides. The method worked well with bioactive substrates such as cholesterol, levulinic acid, and linoleic acid. Wide substrate scope, operational simplicity
An efficient three-component synthesis of coumarin-3-carbamides by use of Ni–NiO nanoparticles as magnetically separable catalyst
作者:Nayim Sepay、Chayan Guha、Arpan Kool、Asok K. Mallik
DOI:10.1039/c5ra13932e
日期:——
An efficient and ecofriendly synthesis of coumarin-3-carbamides has been developed by a three-component reaction of 2-hydroxybenzaldehydes, aliphatic amines (p-/s-) and diethyl malonate using Ni–NiO nanoparticles as catalyst.
[EN] METHODS AND COMPOSITIONS FOR DIAGNOSTIC AND THERAPEUTIC TARGETING OF COX-2<br/>[FR] MÉTHODES ET COMPOSITIONS DE DIAGNOSTIC ET DE CIBLAGE THÉRAPEUTIQUE DE COX-2
申请人:UNIV VANDERBILT
公开号:WO2007149456A2
公开(公告)日:2007-12-27
[EN] The presently disclosed subject matter provides compositions that selectively bind cyclooxygenase-2 and comprise a therapeutic and/or diagnostic moiety. Also provided are methods for using the disclosed compositions for diagnosing (i.e., by imaging) a target cell and/or treating a disorder associated with a cyclooxygenase-2 biological activity. [FR] La présente invention a pour objet des compositions qui se lient de façon sélective à la cyclooxygénase-2 et qui comprennent une fonction thérapeutique et/ou diagnostique. La présente invention concerne également des méthodes d'emploi des compositions décrites dans le diagnostic (c'est-à-dire par imagerie) d'une cellule cible et/ou de traitement d'un trouble associé avec l'activité biologique d'une cyclooxygénase-2.