2-苄基磺酰基-4-氯-6-甲氧基嘧啶 | 116040-08-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 中文名称: 2-苄基磺酰基-4-氯-6-甲氧基嘧啶
• 英文名称: 4-Chloro-6-methoxy-2-benzylsulfonylpyrimidine
• 英文别名: 4-Chloro-6-methoxy-2-(phenylmethanesulfonyl)pyrimidine；2-benzylsulfonyl-4-chloro-6-methoxypyrimidine
• CAS: 116040-08-5
• 化学式: C₁₂H₁₁ClN₂O₃S
• 分子量: 298.75
• InChiKey: LYVALUBCMBTFOV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  77.5
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-苄基磺酰基-4-氯-6-甲氧基嘧啶 在 sodium hydroxide 、 sodium hydride 作用下， 以 甲醇 、 苯 为溶剂， 反应 3.0h， 生成 2-(4'-chloro-6'-methoxypyrimidine-2'-yl)oxy benzoic acid
  参考文献：
  名称：

  Dimethoxypyrimidines as Novel Herbicides. Part 2. Synthesis and Herbicidal Activity ofO-Pyrimidinylsalicylates and Analogues

  摘要：

  A new series of the O-pyrimidinylsalicylates was synthesized and their herbicidal activity was examined. Some of these compounds showed very strong herbicidal activity under pre- and post-emergent treatment conditions against various kinds of grass and broadleaf weeds. Among these compounds, O-(4, 6-dimethoxypyrimidin-2-yl) salicylic acid and its methyl ester were found to exhibit the highest activity. The herbicidal symptoms observed after the treatments included early cessation of plant growth followed by chlorosis, necrosis and plant death. The symptoms were similar to those caused by sulfonylureas and imidazolinones, which inhibit branched-chain amino acid biosynthesis.

  DOI：

  10.1002/(sici)1096-9063(199606)47:2<115::aid-ps397>3.0.co;2-r
• 作为产物：
  描述：

  2-Benzylthio-4-chloro-6-methoxypyrimidine 在 Oxone 作用下， 以 水 为溶剂， 反应 3.0h， 以95.8%的产率得到2-苄基磺酰基-4-氯-6-甲氧基嘧啶
  参考文献：
  名称：

  Dimethoxypyrimidines as Novel Herbicides. Part 2. Synthesis and Herbicidal Activity ofO-Pyrimidinylsalicylates and Analogues

  摘要：

  A new series of the O-pyrimidinylsalicylates was synthesized and their herbicidal activity was examined. Some of these compounds showed very strong herbicidal activity under pre- and post-emergent treatment conditions against various kinds of grass and broadleaf weeds. Among these compounds, O-(4, 6-dimethoxypyrimidin-2-yl) salicylic acid and its methyl ester were found to exhibit the highest activity. The herbicidal symptoms observed after the treatments included early cessation of plant growth followed by chlorosis, necrosis and plant death. The symptoms were similar to those caused by sulfonylureas and imidazolinones, which inhibit branched-chain amino acid biosynthesis.

  DOI：

  10.1002/(sici)1096-9063(199606)47:2<115::aid-ps397>3.0.co;2-r

文献信息

• Pyrimidine derivatives and agricultural or horticultural fungicidal composition contaning the same
  申请人：KUMIAI CHEMICAL INDUSTRY CO., LTD.

  公开号：EP0270111B1

  公开（公告）日：1991-05-15
• US4992438A
  申请人：——

  公开号：US4992438A

  公开（公告）日：1991-02-12
• Dimethoxypyrimidines as Novel Herbicides. Part 2. Synthesis and Herbicidal Activity of<i>O</i>-Pyrimidinylsalicylates and Analogues
  作者：Yukio Nezu、Masahiro Miyazaki、Kazuhiko Sugiyama、Nobuhide Wada、Ikuo Kajiwara、Takeshige Miyazawa

  DOI：10.1002/(sici)1096-9063(199606)47:2<115::aid-ps397>3.0.co;2-r

  日期：1996.6

  A new series of the O-pyrimidinylsalicylates was synthesized and their herbicidal activity was examined. Some of these compounds showed very strong herbicidal activity under pre- and post-emergent treatment conditions against various kinds of grass and broadleaf weeds. Among these compounds, O-(4, 6-dimethoxypyrimidin-2-yl) salicylic acid and its methyl ester were found to exhibit the highest activity. The herbicidal symptoms observed after the treatments included early cessation of plant growth followed by chlorosis, necrosis and plant death. The symptoms were similar to those caused by sulfonylureas and imidazolinones, which inhibit branched-chain amino acid biosynthesis.