7,7,9,9-Tetramethyl-8-oxa-7,9-disilaheptacyclo[13.6.6.02,14.04,12.06,10.016,21.022,27]heptacosa-2(14),3,5,10,12,16,18,20,22,24,26-undecaene | 1244739-23-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 并四苯
• 英文名称: 7,7,9,9-Tetramethyl-8-oxa-7,9-disilaheptacyclo[13.6.6.02,14.04,12.06,10.016,21.022,27]heptacosa-2(14),3,5,10,12,16,18,20,22,24,26-undecaene
• CAS: 1244739-23-8
• 化学式: C₂₈H₂₆OSi₂
• 分子量: 434.685
• InChiKey: VRBOJINUMUEKPS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.68
• 重原子数：
  31
• 可旋转键数：
  0
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-吡咯甲酸叔丁酯 、 7,7,9,9-Tetramethyl-8-oxa-7,9-disilaheptacyclo[13.6.6.02,14.04,12.06,10.016,21.022,27]heptacosa-2(14),3,5,10,12,16,18,20,22,24,26-undecaene 在 三氟甲磺酸 、 碘苯二乙酸 、 potassium fluoride 、 四丁基氟化铵 作用下， 以 二氯甲烷 、 四氢呋喃 为溶剂， 反应 13.0h， 以45%的产率得到tert-butyl 29-azaoctacyclo[14.6.6.17,10.02,15.04,13.06,11.017,22.023,28]nonacosa-2,4,6(11),8,12,14,17,19,21,23,25,27-dodecaene-29-carboxylate
  参考文献：
  名称：

  Oxadisilole Fused Triptycene and Extended Triptycene: Precursors of Triptycyne and Extended Triptycyne

  摘要：

  With benzobisoxadisilole 1 as a 1,4-benzdiyne equivalent, oxadisilole fused triptycene Sand extended triptycene 6 were synthesized. Triptycenes 5 and 6 are new precursors of triptycyne 7 and extended triptycyne 8 respectively via the phenyliodination/fluoride induced elimination protocol. Using these two arynes, a series or triptycene derivatives Were synthesized.

  DOI：

  10.1021/jo1016025
• 作为产物：
  描述：

  7,7,9,9-tetramethyl-8,28-dioxa-7,9-disilaoctacyclo[13.6.6.13,13.02,14.04,12.06,10.016,21.022,27]octacosa-4,6(10),11,16,18,20,22,24,26-nonaene 在 乙酸酐 、 溶剂黄146 作用下， 反应 12.0h， 以81%的产率得到7,7,9,9-Tetramethyl-8-oxa-7,9-disilaheptacyclo[13.6.6.02,14.04,12.06,10.016,21.022,27]heptacosa-2(14),3,5,10,12,16,18,20,22,24,26-undecaene
  参考文献：
  名称：

  Oxadisilole Fused Triptycene and Extended Triptycene: Precursors of Triptycyne and Extended Triptycyne

  摘要：

  With benzobisoxadisilole 1 as a 1,4-benzdiyne equivalent, oxadisilole fused triptycene Sand extended triptycene 6 were synthesized. Triptycenes 5 and 6 are new precursors of triptycyne 7 and extended triptycyne 8 respectively via the phenyliodination/fluoride induced elimination protocol. Using these two arynes, a series or triptycene derivatives Were synthesized.

  DOI：

  10.1021/jo1016025

文献信息

• Anthracene Capped Isobenzofuran: A Synthon for the Preparations of Iptycenes and Iptycene Quinones
  作者：Bao-Jian Pei、Wing-Hong Chan、Albert W. M. Lee

  DOI：10.1021/ol200309v

  日期：2011.4.1

  Anthracene capped isobenzofuran 5 (5,6-(9,10-dihydroanthracen-9,10-yl)isobenzofuran) was synthesized for the first time. It is a highly reactive and versatile synthon for the synthesis of iptycene derivatives via Diels−Alder reactions. Cycloadducts 10 could be readily deoxygenated to iptycenes 11. Two new reactions of PhI(OAc)2/TfOH have been explored. Endoxides 10 were directly oxidized to iptycene

  首次合成了蒽封端的异苯并呋喃5（5,6-（9,10-二氢蒽-9,10-基）异苯并呋喃）。它是一种高反应性且用途广泛的合成子，可通过Diels-Alder反应合成iptycene衍生物。Cycloadducts 10可以容易地脱氧到iptycenes 11。已探索了PhI（OAc）2 / TfOH的两个新反应。内氧化物10被直接氧化为并茂苯醌12，而异苯并呋喃5方便地转化为三并苯二醛16。H形中央延伸的戊烯并茂醌13和14 也被合成了。
• Oxadisilole Fused Triptycene and Extended Triptycene: Precursors of Triptycyne and Extended Triptycyne
  作者：Bao-Jian Pei、Wing-Hong Chan、Albert W. M. Lee

  DOI：10.1021/jo1016025

  日期：2010.11.5

  With benzobisoxadisilole 1 as a 1,4-benzdiyne equivalent, oxadisilole fused triptycene Sand extended triptycene 6 were synthesized. Triptycenes 5 and 6 are new precursors of triptycyne 7 and extended triptycyne 8 respectively via the phenyliodination/fluoride induced elimination protocol. Using these two arynes, a series or triptycene derivatives Were synthesized.