2-methyl-3-vinyloxy-4-methoxymethyl-5-vinyloxymethylpyridine | 137813-01-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-methyl-3-vinyloxy-4-methoxymethyl-5-vinyloxymethylpyridine
• 英文别名: 2-Methyl-3-vinyloxy-4-methoxymethyl-5-vinyloxymethylpyridine；3-ethenoxy-5-(ethenoxymethyl)-4-(methoxymethyl)-2-methylpyridine
• CAS: 137813-01-5
• 化学式: C₁₃H₁₇NO₃
• 分子量: 235.283
• InChiKey: LWUCXZQQYCZULB-UHFFFAOYSA-N

物化性质

• 沸点：
  337.0±42.0 °C(Predicted)
• 密度：
  1.048±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  40.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  银杏酮盐酸盐 、 乙炔 在 氢氧化钾 作用下， 以 1,4-二氧六环 为溶剂， 反应 1.0h， 以26%的产率得到2-methyl-3-vinyloxy-4-methoxymethyl-5-vinyloxymethylpyridine
  参考文献：
  名称：

  An unusual spatial structure of di-ortho-substituted hetaryl vinyl ethers according to1H and13C NMR data

  摘要：

  According to H-1 and C-13 NMR data, 2,6-dimethyl-3,5-dichloro-4-vinyloxy-pyridine and 2-methyl-4-methoxymethyl-5-hydroxymethyl-3-vinyloxypyridine exist predominantly as the sterically hindered s-cis conformation, with the angle between the hetaryl ring and the vinyloxypyridine plane about 60-degrees.

  DOI：

  10.1007/bf00960407

文献信息

• An unusual spatial structure of di-ortho-substituted hetaryl vinyl ethers according to1H and13C NMR data
  作者：A. V. Afonin、M. A. Andriyankov、V. K. Voronov、M. V. Nikitin

  DOI：10.1007/bf00960407

  日期：1991.9

  According to H-1 and C-13 NMR data, 2,6-dimethyl-3,5-dichloro-4-vinyloxy-pyridine and 2-methyl-4-methoxymethyl-5-hydroxymethyl-3-vinyloxypyridine exist predominantly as the sterically hindered s-cis conformation, with the angle between the hetaryl ring and the vinyloxypyridine plane about 60-degrees.