4,5-bis(ethoxycarbonyl)phthalic acid | 343234-33-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,5-bis(ethoxycarbonyl)phthalic acid
• CAS: 343234-33-3
• 化学式: C₁₄H₁₄O₈
• 分子量: 310.26
• InChiKey: KINKSULVWLKFFG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  22
• 可旋转键数：
  8
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  127
• 氢给体数：
  2
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  diethyl 1,3-dioxo-1,3-dihydroisobenzofuran-5,6-dicarboxylate 在 水 、 溶剂黄146 作用下， 反应 0.5h， 以94%的产率得到4,5-bis(ethoxycarbonyl)phthalic acid
  参考文献：
  名称：

  均苯四酸的酯。第一部分：非手性醇的酯：部分和混合的均苯四甲酸酯酯的区域选择性合成，使用原甲酸酯酯对均苯四甲酸酯体系进行定量酯化的酯交换反应机理以及邻苯二甲酸酯二酸酯取代模式的简便合成

  摘要：

  温和的条件和可逆酸酐的形成允许在酯化过程中对均苯四甲酸二酐（PMDA，苯-1,2,4,5-四羧酸二酐）的四个当量羰基进行相对区分，从而导致区域选择性方法产生广泛的部分或全部酯化的产品或在不同位置带有不同酯化基团的产品。均苯四甲酸单酯酸酐在二氯甲烷/三乙胺中由1当量的醇有效形成。在相同条件下，两个不同可以使醇顺序地反应。用2当量的醇，获得通常的间位和对位二酯混合物，通过与HOAc结晶分离。间苯二甲酸和对二苄基均苯四酸酯通过进一步酯化然后氢解而充当其他二酯的区域特异性来源。发现回流的原甲酸三酯能定量在自催化条件下均苯四甲酸体系的酯化; 与预先存在的酯进行的少量酯交换（占总产物的0-5％）归因于可逆酸酐的形成。为了用醇进行一般的酯化反应，使用草酰氯获得了部分酯酰氯。均苯四甲酸三酯在蒸馏时提供邻二酯酸酐，从而提供了进入该系统中最新颖的邻位取代模式的容易途径。通过选择性皂化或通过预先引入一个苄基酯取

  DOI：

  10.1021/jo800543w

文献信息

• Method for hydrogenating organic compounds by means of ru/sio2 catalysts
  申请人：——

  公开号：US20040199033A1

  公开（公告）日：2004-10-07

  In a process for hydrogenating at least one organic compound, the organic compound or compounds is/are brought into contact with a hydrogen-containing gas in the presence of a catalyst which comprises, as active metal, ruthenium either alone or together with at least one further metal of transition group I, VII or VIII of the Periodic Table applied to a support material based on amorphons silicon dioxide and is obtainable by: i) a single or multiple treatment of a support material based on amorphous silicon dioxide with a halogen-free aqueous solution of a low molecular weight ruthenium compound and subsequent drying of the treated support material at below 200° C., ii) reduction of the solid obtained in i) by means of hydrogen at from 100 to 350° C., with step ii) being carried out directly after step i).

  在至少一种有机化合物氢化的过程中，有机化合物或化合物被带入含氢气体中，在催化剂的存在下，该催化剂包括作为活性金属的钌单独或与周期表的I，VII或VIII族过渡金属中的至少一种进一步金属一起应用于基于非晶态二氧化硅的支撑材料，并且可以通过以下方式获得：i）用不含卤素的低分子量钌化合物的水溶液对基于非晶态二氧化硅的支撑材料进行单次或多次处理，并在低于200°C的条件下干燥处理所处理的支撑材料，ii）通过在100°C至350°C的温度下用氢还原i）中得到的固体，其中步骤ii）直接在步骤i）之后进行。
• Melt-fusible polyimides
  申请人：E.I. DU PONT DE NEMOURS AND COMPANY

  公开号：EP0122060A2

  公开（公告）日：1984-10-17

  Melt-fusible polyimides based on pyromellitic dianhydride and at least one defined aromatic diamine are useful in making low-void composites and thermoplastic tapes, which can be fabricated into articles such as, for example, aircraft and autobody panels, printed circuit boards, etc. Some of these polyimides are melt-processible and can be fabricated by conventional procedures such as extrusion and injection molding.

  基于吡咯烷二酸酐和至少一种确定的芳香族二胺的可熔融聚酰亚胺可用于制造低空隙复合材料和热塑性胶带，这些材料可制成诸如飞机和汽车车身面板、印刷电路板等物品。其中一些聚酰亚胺可熔融加工，可通过挤出和注塑等传统工艺制造。
• Integrated circuit device and process for its manufacture
  申请人：INTERNATIONAL BUSINESS MACHINES CORPORATION

  公开号：EP0838853A2

  公开（公告）日：1998-04-29

  The invention relates to an integrated circuit device comprising (i) a substrate; (ii) metallic circuit lines positioned on the substrate and (iii) a dielectric material positioned on the circuit lines. The dielectric material comprises the reaction product of an organic polysilica and polyamic ester preferably terminated with an alkoxysilyl alkyl group.

  本发明涉及一种集成电路装置，包括(i)基板；(ii)设置在基板上的金属电路线和 (iii)设置在电路线上的介电材料。介电材料包括有机聚硅氧烷和聚氨基酯的反应产物，最好是以烷氧基硅烷基为端基。
• Polyamic acid and polyimide microfine particles and processes for their production
  申请人：OSAKA PREFECTURAL GOVERNMENT

  公开号：EP0982343A2

  公开（公告）日：2000-03-01

  A process for producing polyimide microfine particles which is amenable to free control of particle morphology and particle diameter distribution is provided. A polyamic acid and a polyimide, each in the form of microfine particles with good monodispersibility, are also provided. There is also provided a process for producing polyimide microfine particles from a tetracarboxylic anhydride and a diamine compound which comprises (a) a first step of preparing a first solution containing the tetracarboxylic anhydride and a second solution containing the diamine compound, (b) a second step of mixing the first and second solutions and causing a polyamic acid to precipitate in the form of microfine particles from the mixed solution under ultrasonic agitation, and (c) a third step of imidating the polyamic acid particles to provide the objection polyimide in the form of microfine particles.

  本发明提供了一种生产聚酰亚胺微细颗粒的工艺，可自由控制颗粒形态和颗粒直径分布。本发明还提供了一种聚酰胺酸和一种聚酰亚胺，它们都是具有良好单分散性的微细颗粒形式。还提供了一种用四羧酸酐和二胺化合物生产聚酰亚胺微细颗粒的工艺，该工艺包括 (a) 第一步，制备含有四羧酸酐的第一溶液和含有二胺化合物的第二溶液、(b) 第二步，将第一和第二溶液混合，并在超声波搅拌下使聚酰胺以微细颗粒的形 式从混合溶液中析出，以及 (c) 第三步，将聚酰胺颗粒酰亚胺化，以微细颗粒的形式提供反对聚酰亚胺。
• Thermosetting polyamic acid microfine particles, thermosetting polyimide microfine particles, crosslinked polyimide microfine particles, and processes for their production
  申请人：OSAKA PREFECTURAL GOVERNMENT

  公开号：EP1152021A1

  公开（公告）日：2001-11-07

  An object of the invention is to provide thermosetting amic acid microfine particles, thermosetting imide microfine particles and crosslinked imide microfine particles of controlled particle shape and size distribution. The invention provides a production technology which comprises mixing a first solution containing a tetracarboxylic anhydride and a C=C bond-containing acid anhydride with a second solution containing a diamine compound, causing precipitation of thermosetting amic acid microfine particles from the resulting mixture, and further producing thermosetting imide microfine particles and crosslinked imide microfine particles from the thermosetting amic acid microfine particles.

  本发明的目的是提供粒形和粒度分布可控的热固性胺基酸微细颗粒、热固性酰亚胺微细颗粒和交联酰亚胺微细颗粒。本发明提供了一种生产技术，包括将含有四羧酸酐和含 C=C 键酸酐的第一种溶液与含有二胺化合物的第二种溶液混合，使热固性酰胺微细颗粒从所得混合物中沉淀，并进一步用热固性酰胺微细颗粒生产热固性酰亚胺微细颗粒和交联酰亚胺微细颗粒。