N,N'-p-phenylene-bis-diacetamide | 54009-65-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N'-p-phenylene-bis-diacetamide
• 英文别名: Tetra-N-acetyl-p-phenylendiamin；N,N'-p-Phenylen-bis-diacetamid；N-acetyl-N-[4-(diacetylamino)phenyl]acetamide
• CAS: 54009-65-3
• 化学式: C₁₄H₁₆N₂O₄
• 分子量: 276.292
• InChiKey: ZTCWRVGEKCPIAD-UHFFFAOYSA-N

物化性质

• 熔点：
  207 °C
• 沸点：
  598.7±20.0 °C(Predicted)
• 密度：
  1.256±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  74.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  乙酸酐 、 对苯二胺硫酸盐 在 sodium acetate 作用下， 生成 N,N'-二乙酰-1,4-苯二胺 、 N,N'-p-phenylene-bis-diacetamide
  参考文献：
  名称：

  Zum Problem der Anaphylaxie mit chemisch bekannten Substanzen

  摘要：

  I 1.琥珀酸偶氮蛋白vorbehandelten Meerschweinchen Konn mitBis-p-succinanilsäure-azo-resorcinF im Schultz - Dale's chen Versuch gelegentlich den anaphylaktischen Schockauslösen。达斯IST EINEBestätigung德Versuche冯兰斯坦纳UND的van der Scheer的0.1 。

  DOI：

  10.1002/hlca.19390220102

文献信息

• [EN] COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS<br/>[FR] COMPOSITIONS ET PROCÉDÉS D'ADMINISTRATION D'ACIDES NUCLÉIQUES
  申请人：POSEIDA THERAPEUTICS INC

  公开号：WO2022087148A1

  公开（公告）日：2022-04-28

  The present disclosure provides compositions and methods for the genetic modification of cells, including, but not limited to, resting T-cells and hepatocytes. The compositions and methods can comprise lipid nanoparticles, wherein the lipid nanoparticles comprise at least one multivalent cationic bolaform amphiphilic lipid, at least one structural lipid, at least one phospholipid and at least one PEGylated lipid.

  本公开提供了细胞基因修饰的组合物和方法，包括但不限于静止的T细胞和肝细胞。该组合物和方法可以包括脂质纳米粒子，其中脂质纳米粒子包括至少一种多价阳离子球形两亲性脂质、至少一种结构脂质、至少一种磷脂和至少一种PEG化脂质。
• JPS61200173A
  申请人：——

  公开号：JPS61200173A

  公开（公告）日：1986-09-04
• Flexible Metal-Clad Laminate and Manufacturing Method Thereof
  申请人：You Hong

  公开号：US20120070677A1

  公开（公告）日：2012-03-22

  Provided are a flexible metal clad laminate and a method for manufacturing the same. The flexible metal clad laminate is obtained by applying a polyimide precursor resin convertible into a polyimide resin many times onto a metal clad, followed by drying, and by converting the polyimide precursor resin into a polyimide resin through infrared ray (IR) heat treatment. The polyimide resin layer that is in direct contact with the metal clad has a glass transition temperature of 300° C. or higher, and the polyimide resin layer has an overall linear thermal expansion coefficient of 20 ppm/K or lower. It is possible to obtain a flexible metal clad laminate for flexible printed circuit boards that causes no curling before and after etching, shows a small change in dimension caused by heat treatment, and has high adhesion to a metal clad and excellent appearance after completing imidization.
• Coatable Polymer Polarizer
  申请人：Light Polymers Holding

  公开号：US20160266292A1

  公开（公告）日：2016-09-15

  A coatable polymer polarizer may be formed with a composition that includes a rigid rod-like polymer capable of forming a liquid crystal phase in a solvent. The rigid rod-like polymer may form an achromatic polarizer.
• US4144225A
  申请人：——

  公开号：US4144225A

  公开（公告）日：1979-03-13